| 1 | Golden Spread Electric Cooperative INC | Unclassified | $546.1M | $1.4B |
| 2 | High Plains Christian Ministries Foundation | Human Services | $125.6M | $575.8M |
| 3 | American Quarter Horse Association | Unclassified | $113.1M | $95.1M |
| 4 | Cal Farleys Boys Ranch Foundation | Human Services | $79.7M | $458.7M |
| 5 | Amarillo Area Foundation INC | Philanthropy, Voluntarism & Grantmaking | $61.6M | $171.6M |
| 6 | Cal Farleys Boys Ranch | Human Services | $59.9M | $158.5M |
| 7 | American Quarter Horse Foundation | Animal-Related | $48.3M | $71.9M |
| 8 | Baptist Community Services | Human Services | $42.3M | $98.6M |
| 9 | Education Credit Union | Unclassified | $39.8M | $467.8M |
| 10 | Panhandle Community Services | Human Services | $33.8M | $17.4M |
| 11 | Christian Ophthalmic Surgery Expedition Network | Human Services | $29.2M | $18.4M |
| 12 | Norman H Read 1985 Trust | Philanthropy, Voluntarism & Grantmaking | $26.4M | $70.2M |
| 13 | Don & Sybil Harrington Foundation | Philanthropy, Voluntarism & Grantmaking | $25.2M | $121.3M |
| 14 | High Plains Food Bank | Unclassified | $20.0M | $19.0M |
| 15 | Harrington Cancer and Health Foundation | Unclassified | $19.6M | $67.9M |
| 16 | Craig Amarillo LLC | Human Services | $17.1M | $50.3M |
| 17 | Paul F and Virginia J Engler Foundation | Unclassified | $15.6M | $35.4M |
| 18 | Amarillo Multiservice Center for the Aging INC | Human Services | $15.1M | $30.8M |
| 19 | Christian Relief Fund | International, Foreign Affairs & National Security | $14.0M | $16.9M |
| 20 | Access Community Credit Union | Unclassified | $12.9M | $196.5M |
| 21 | Brumley Foundation | Unclassified | $12.9M | $22.9M |
| 22 | Advo Companies INC | Human Services | $10.6M | $1.3M |
| 23 | Amarillo Country Club INC | Unclassified | $10.3M | $7.6M |
| 24 | Mary E Bivins Foundation | Housing & Shelter | $10.3M | $139.2M |
| 25 | Ware Foundation | Philanthropy, Voluntarism & Grantmaking | $10.1M | $19.8M |
| 26 | Catholic Family Service INC | Human Services | $10.0M | $4.4M |
| 27 | Amarillo College Foundation INC | Unclassified | $9.0M | $91.2M |
| 28 | Don Harrington Discovery Center Foundation INC | Arts, Culture & Humanities | $7.4M | $11.7M |
| 29 | Llano Cemetery Association | Unclassified | $7.3M | $18.3M |
| 30 | Waite and Genevieve Phillips Foundation | Unclassified | $6.5M | $8.6M |
| 31 | Kids INC of Amarillo Texas | Recreation & Sports | $6.5M | $25.2M |
| 32 | Atc Health Promotion Foundation | Health Care | $6.3M | $20.3M |
| 33 | Texas Cattle Feeders Association | Unclassified | $6.2M | $8.2M |
| 34 | Amarillo Symphony INC | Arts, Culture & Humanities | $6.1M | $6.9M |
| 35 | The United Way INC | Unclassified | $4.7M | $7.3M |
| 36 | Anna Belle Kritser II Foundation | Philanthropy, Voluntarism & Grantmaking | $4.3M | $5.3M |
| 37 | Turn Center | Health Care | $4.3M | $6.4M |
| 38 | Amarillo Tri-state Exposition | Recreation & Sports | $4.1M | $6.7M |
| 39 | Presbyterian Home for Children | Human Services | $4.1M | $20.2M |
| 40 | Opportunity School INC | Unclassified | $4.1M | $9.8M |
| 41 | Family Support Services of Amarillo | Human Services | $4.0M | $6.8M |
| 42 | Downtown Womens Center | Unclassified | $3.9M | $4.7M |
| 43 | High Plains Childrens Home and Family Services | Unclassified | $3.9M | $10.7M |
| 44 | Panhandle Aids Support Organization INC | Diseases, Disorders & Medical Disciplines | $3.7M | $2.1M |
| 45 | Coalition of Health Services INC | Health Care | $3.6M | $845K |
| 46 | Mary E Bivins Trust | Unclassified | $3.6M | $20.6M |
| 47 | International Brotherhood of Electrical Workers | Unclassified | $3.5M | $3.3M |
| 48 | Turn Center Foundation INC | Unclassified | $3.2M | $8.0M |
| 49 | Heal the City Free Clinic | Health Care | $3.2M | $8.5M |
| 50 | Josephine Anderson Charitable Trust | Unclassified | $3.1M | $6.2M |
| 51 | International Brotherhood Teamsters | Unclassified | $3.1M | $4.7M |
| 52 | Haven Health Clinics | Health Care | $3.1M | $2.6M |
| 53 | Childrens Learning Centers of Amarillo INC | Unclassified | $3.0M | $7.2M |
| 54 | Amarillo Club INC | Unclassified | $2.9M | $1.4M |
| 55 | R G & Claudine Pope Peeler Charitable Tr | Youth Development | $2.8M | $8.5M |
| 56 | Hope to Opportunities Foundation | Philanthropy, Voluntarism & Grantmaking | $2.7M | $6.5M |
| 57 | Faith City INC | Human Services | $2.6M | $9.2M |
| 58 | Amarillo Art Center Association | Arts, Culture & Humanities | $2.4M | $4.5M |
| 59 | Meals on Wheels of Amarillo Texas INC | Food, Agriculture & Nutrition | $2.4M | $11.8M |
| 60 | Boy Scouts of America | Unclassified | $2.4M | $12.1M |
| 61 | Dr Kent Roberts and Ilene Roberts Balliett Foundation | Philanthropy, Voluntarism & Grantmaking | $2.3M | $7.1M |
| 62 | San Jacinto Christian Academy | Education | $2.3M | $2.4M |
| 63 | Hope Choice INC | Health Care | $2.2M | $5.9M |
| 64 | Hcf Supporting Organization | Diseases, Disorders & Medical Disciplines | $2.1M | $9.2M |
| 65 | Kimble Foundation Trust | Philanthropy, Voluntarism & Grantmaking | $2.1M | $4.1M |
| 66 | Working Ranch Cowboys Association | Unclassified | $2.1M | $1.6M |
| 67 | Street Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.0M | $2.0M |
| 68 | Ascension Academy | Education | $2.0M | $7.4M |
| 69 | Will Rogers Range Riders Foundation | Diseases, Disorders & Medical Disciplines | $1.9M | $1.8M |
| 70 | Msk Mission Foundation INC | Religion-Related | $1.9M | $2.0M |
| 71 | The Bridge | Human Services | $1.9M | $4.4M |
| 72 | Bonnie Bob Carson Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $1.8M | $1.3M |
| 73 | Bradley Family Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $1.8M | $5.9M |
| 74 | Frances E Maddox Foundation | Housing & Shelter | $1.7M | $5.2M |
| 75 | Coffee Memorial Blood Center Foundation | Health Care | $1.7M | $8.1M |
| 76 | West Texas Cutting Horse Association | Unclassified | $1.7M | $324K |
| 77 | The Maverick Boys and Girls Club of Amarillo INC | Youth Development | $1.7M | $2.3M |
| 78 | 100 Club of Amarillo INC | Crime & Legal-Related | $1.7M | $1.1M |
| 79 | Amarillo Wesley Community Center INC | Unclassified | $1.5M | $3.4M |
| 80 | Amarillo Montessori Academy | Unclassified | $1.5M | $1.2M |
| 81 | Transformation Park | Housing & Shelter | $1.5M | $1.2M |
| 82 | Lee Bivins Foundation | Housing & Shelter | $1.5M | $5.9M |
| 83 | Lone Star Ballet INC | Unclassified | $1.5M | $2.6M |
| 84 | Panhandle Independent Living Center INC | Human Services | $1.5M | $759K |
| 85 | Amarillo Association of Realtors INC | Unclassified | $1.5M | $1.8M |
| 86 | Working Ranch Cowboys Foundation | Education | $1.4M | $2.0M |
| 87 | Amarillo Business Foundation | Philanthropy, Voluntarism & Grantmaking | $1.4M | $4.2M |
| 88 | Ronald McDonald House Charities of Amarillo INC | Diseases, Disorders & Medical Disciplines | $1.3M | $6.4M |
| 89 | High Plains Childrens Home and Family Services Foundation INC | Human Services | $1.3M | $3.9M |
| 90 | Amarillo Chamber of Commerce | Unclassified | $1.3M | $1.5M |
| 91 | Amarillo Little Theatre INC | Arts, Culture & Humanities | $1.3M | $1.7M |
| 92 | Another Chance House | Human Services | $1.2M | $2.1M |
| 93 | The Julia at Williams Irrv Tr | Philanthropy, Voluntarism & Grantmaking | $1.2M | $1.6M |
| 94 | Citychurch Outreach Ministry | Education | $1.2M | $567K |
| 95 | C J and Syble Fowlston Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $1.2M | $5.4M |
| 96 | The Crouch Foundation | Philanthropy, Voluntarism & Grantmaking | $1.1M | $16.6M |
| 97 | Cloninger Angel Fire Foundation | Philanthropy, Voluntarism & Grantmaking | $1.1M | $5.1M |
| 98 | Amarillo Xtreme Volleyball | Recreation & Sports | $1.1M | $0 |
| 99 | Animal Rescue Shelter INC | Animal-Related | $1.1M | $3.4M |
| 100 | Teas Foundation | Philanthropy, Voluntarism & Grantmaking | $1.1M | $3.0M |