| 1 | River Hills Community Health Center INC | Health Care | $30.0M | $33.0M |
| 2 | Indian Hills Community College Foundation | Education | $19.5M | $40.1M |
| 3 | First Resources Corp. | Employment | $16.2M | $8.0M |
| 4 | Ottumwa Regional Legacy Foundation INC | Health Care | $15.2M | $73.8M |
| 5 | Southern Iowa Economic Development Association | Unclassified | $12.7M | $5.4M |
| 6 | Southern Iowa Mental Health Center | Mental Health & Crisis Intervention | $5.9M | $6.6M |
| 7 | American Home Finding Association | Human Services | $5.3M | $2.5M |
| 8 | Southeast Iowa Sports Commission | Recreation & Sports | $4.0M | $8.6M |
| 9 | Hospice | Unclassified | $2.5M | $2.4M |
| 10 | Wapello County Foundation | Unclassified | $2.0M | $1.4M |
| 11 | Young Mens Christian Association of Ottumwa Iowa | Unclassified | $1.6M | $2.7M |
| 12 | Rippling Waters | Housing & Shelter | $1.4M | $2.7M |
| 13 | Ottumwa Christian School | Education | $1.0M | $392K |
| 14 | Indian Hills Community College Development INC | Unclassified | $914K | $3.4M |
| 15 | International Union United Auto Aerospace & Agricultural Workers | Unclassified | $635K | $471K |
| 16 | Crisis Center & Womens Shelter INC | Human Services | $635K | $596K |
| 17 | Ahead INC | Housing & Shelter | $587K | $3.5M |
| 18 | Ottumwa Area Chamber of Commerce | Unclassified | $546K | $941K |
| 19 | Ottumwa Public Library Foundation | Education | $545K | $1.8M |
| 20 | United Way of Wapello County Iowa INC | Philanthropy, Voluntarism & Grantmaking | $503K | $2.4M |
| 21 | Bridge View Center INC | Arts, Culture & Humanities | $497K | $5.6M |
| 22 | Regional Service Guild | Health Care | $481K | $536K |
| 23 | Heartland Humane Society Ltd | Animal-Related | $367K | $711K |
| 24 | Tenco Foundation INC | Unclassified | $353K | $757K |
| 25 | American Gothic Performing Arts | Arts, Culture & Humanities | $341K | $90K |
| 26 | Main Street Ottumwa | Unclassified | $282K | $221K |
| 27 | Edward J Schwartz Perpetual Educational Tr Fund | Unclassified | $266K | $775K |
| 28 | Southeast Iowa Donors INC | Philanthropy, Voluntarism & Grantmaking | $262K | $960K |
| 29 | Wapello County 4-H Exposition INC | Recreation & Sports | $240K | $1.3M |
| 30 | American Legion | Public & Societal Benefit | $227K | $225K |
| 31 | Ecumenical Lords Cupboard | Unclassified | $220K | $378K |
| 32 | Izaak Walton League Ottumwa Chapter | Environment | $216K | $348K |
| 33 | Whatsoever You Do | Housing & Shelter | $205K | $1.0M |
| 34 | Shaul Cemetery Assn INC | Unclassified | $198K | $121K |
| 35 | Fraternal Order of Eagles | Unclassified | $185K | $199K |
| 36 | American Home Finding Endowment Fund for Children | Unclassified | $165K | $2.4M |
| 37 | Air Power Museum INC | Arts, Culture & Humanities | $161K | $2.8M |
| 38 | Ottumwa Athletic Club INC | Education | $156K | $196K |
| 39 | Benevolent & Protective Order of Elks of the USA | Unclassified | $150K | $246K |
| 40 | Knights of Columbus | Unclassified | $136K | $73K |
| 41 | Little League Baseball INC | Unclassified | $133K | $51K |
| 42 | Wapello County Trails Council | Recreation & Sports | $124K | $207K |
| 43 | Ottumwa Symophony Orchestra Foundation | Unclassified | $108K | $421K |
| 44 | Iowa Farm Bureau Federation | Unclassified | $104K | $1.2M |
| 45 | Greater Ottumwa Development Foundation | Community Improvement & Capacity Building | $103K | $74K |
| 46 | Friends of Nas Ottumwa INC | Arts, Culture & Humanities | $102K | $414K |
| 47 | Rotary International | Unclassified | $85K | $98K |
| 48 | Heartland Pregnancy Center | Health Care | $77K | $152K |
| 49 | Wapello County Sheriffs Posse INC | Unclassified | $73K | $75K |
| 50 | Oktoberfest Committee | Unclassified | $73K | $76K |
| 51 | Ottumwa Park and Recreation Foundation INC | Recreation & Sports | $69K | $46K |
| 52 | Regional Economic Development Investments INC | Community Improvement & Capacity Building | $67K | $2.4M |
| 53 | Wapello County Historical Society | Arts, Culture & Humanities | $62K | $1.5M |
| 54 | Akem | Religion-Related | $60K | $17K |
| 55 | Edward J and Agnes Kurtz Hose Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $53K | $807K |
| 56 | American Society of Radiologic Technologists | Unclassified | $44K | $199K |
| 57 | Southeast Iowa Dream Center INC | Human Services | $41K | $90K |
| 58 | Ottumwa Civic Music Association | Unclassified | $39K | $228K |
| 59 | Peter G Ballingall Estate | Unclassified | $39K | $94K |
| 60 | Zachary Yates Memorial Foundation Ltd | Education | $9K | $63K |
| 61 | Habitat for Humanity International INC | Unclassified | $9K | $546K |
| 62 | Ottumwa Babe Ruth Association Ltd Ottumwa Youth Baseball | Recreation & Sports | $7K | $24K |
| 63 | Iglesia Evangelica Belen Assembly of God | Unclassified | $0 | $0 |
| 64 | Wapello County Genealogical Society | Arts, Culture & Humanities | $0 | $0 |
| 65 | Reid Cemetery Association | Mutual & Membership Benefit | $0 | $0 |
| 66 | Kiwanis International INC | Unclassified | $0 | $0 |
| 67 | Robert F Kennedy-martin Luther King Memorial Fund INC | Unclassified | $0 | $0 |
| 68 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 69 | International Association of Lions Clubs | Unclassified | $0 | $0 |
| 70 | Order of the Amaranth INC Supreme Council | Unclassified | $0 | $0 |
| 71 | League of Women Voters of Iowa | Unclassified | $0 | $0 |
| 72 | Modern Woodmen of America | Unclassified | $0 | $0 |
| 73 | Knights of Columbus | Unclassified | $0 | $0 |
| 74 | Fraternal Order of Eagles | Unclassified | $0 | $0 |
| 75 | Order of the Amaranth INC Supreme Council | Unclassified | $0 | $0 |
| 76 | Order of the Amaranth INC | Unclassified | $0 | $0 |
| 77 | Gateway Singers Ministry | Religion-Related | $0 | $0 |
| 78 | Victory Ranch | Health Care | $0 | $0 |
| 79 | Faith Christian Fellowship of Ottumwa | Unclassified | $0 | $0 |
| 80 | Ottumwa Community Childrens Playhouse | Arts, Culture & Humanities | $0 | $0 |
| 81 | Holy Grace Foundation | Health Care | $0 | $0 |
| 82 | Gospel Baptist Church of Frederick Maryland | Religion-Related | $0 | $0 |
| 83 | Ottumwa High School Music Boosters INC | Education | $0 | $0 |
| 84 | Heart for Haiti | Arts, Culture & Humanities | $0 | $0 |
| 85 | Reaching America for Jesus | Religion-Related | $0 | $0 |
| 86 | International Health Reach | Health Care | $0 | $0 |
| 87 | Veterans of Foreign Wars of the United States Dept of Iowa | Unclassified | $0 | $0 |
| 88 | Ancient Free & Accepted Masons of Iowa | Unclassified | $0 | $0 |
| 89 | St. Josephs Roman Catholic Church | Unclassified | $0 | $0 |
| 90 | Wapello County Medical Society INC | Unclassified | $0 | $0 |
| 91 | First Church of the Open Bible | Unclassified | $0 | $0 |
| 92 | Sacred Heart Church | Unclassified | $0 | $0 |
| 93 | Ottumwa Heights College | Unclassified | $0 | $0 |
| 94 | Davis Street Christian Church | Unclassified | $0 | $0 |
| 95 | Ottumwa Pickwick Community Church | Unclassified | $0 | $0 |
| 96 | Ottumwa Area Arts Council | Arts, Culture & Humanities | $0 | $0 |
| 97 | Ottumwa Community Players INC | Arts, Culture & Humanities | $0 | $0 |
| 98 | Iowa Cattlemens Association | Unclassified | $0 | $0 |
| 99 | American Federation of State County & Municipal Employees | Unclassified | $0 | $0 |
| 100 | National Society of the Daughters of the American Revolution | Unclassified | $0 | $0 |