| 1 | East Alabama Medical Center Voluntary Employee Benef Assoc Tru | Mutual & Membership Benefit | $35.7M | $3.6M |
| 2 | Lee County Youth Development Center INC | Crime & Legal-Related | $10.6M | $18.2M |
| 3 | Scott Foundation INC | Philanthropy, Voluntarism & Grantmaking | $8.2M | $12.4M |
| 4 | Opelika Housing Development INC | Housing & Shelter | $6.1M | $23.8M |
| 5 | Saugahatchee Country Club | Unclassified | $5.7M | $6.2M |
| 6 | East Alabama Medical Center Foundation | Unclassified | $5.4M | $34.0M |
| 7 | Easter Seals Alabama INC | Unclassified | $4.9M | $4.2M |
| 8 | Four Corners Ministries | Religion-Related | $3.5M | $5.6M |
| 9 | Alabama Casa Network INC | Civil Rights, Social Action & Advocacy | $2.1M | $772K |
| 10 | Chattahoochee Valley Hospital Society | Health Care | $1.9M | $0 |
| 11 | Harvest Evangelism INC | Mental Health & Crisis Intervention | $1.8M | $1.0M |
| 12 | Mercy Medical Ministry | Health Care | $1.7M | $1.4M |
| 13 | Child Care Resorce Center INC | Human Services | $1.5M | $321K |
| 14 | W James Samford Jr Foundation | Philanthropy, Voluntarism & Grantmaking | $1.4M | $9.3M |
| 15 | Chamber of Commerce Inc-opelika | Unclassified | $1.2M | $376K |
| 16 | Greater Peace Community Development Corporation | Housing & Shelter | $1.0M | $816K |
| 17 | Storybook Farm INC | Recreation & Sports | $1.0M | $1.3M |
| 18 | Envision Opelika Foundation INC | Community Improvement & Capacity Building | $894K | $1.6M |
| 19 | United Way of Lee County INC | Unclassified | $804K | $2.4M |
| 20 | Domestic Violence Intervention Center | Human Services | $759K | $683K |
| 21 | Bethesda Family & Community Development Center INC | Human Services | $733K | $383K |
| 22 | Christ Serv INC | Housing & Shelter | $655K | $1.1M |
| 23 | Auburn Classical Academy INC | Education | $630K | $316K |
| 24 | Christian Services to the Elderly INC | Unclassified | $623K | $1.4M |
| 25 | Opelika Chamber Foundation | Community Improvement & Capacity Building | $611K | $3.6M |
| 26 | Taming Mustangs INC | Religion-Related | $539K | $144K |
| 27 | Bighouse INC | Human Services | $438K | $1.3M |
| 28 | Arts Association of East Alabama | Unclassified | $393K | $135K |
| 29 | Habitat for Humanity International | Unclassified | $391K | $1.8M |
| 30 | Alabama Christian Radio INC | Religion-Related | $383K | $176K |
| 31 | The Way 2 Serve INC | Human Services | $379K | $536K |
| 32 | Mision Vida Nueva | Human Services | $354K | $1.0M |
| 33 | Alabama Association of School Resource Officers | Education | $330K | $53K |
| 34 | Bridge to Life Ministry | Religion-Related | $296K | $252K |
| 35 | Sound Wall Music Initiative | Arts, Culture & Humanities | $280K | $15K |
| 36 | Beauregard Volunteer Fire Dept INC | Unclassified | $224K | $978K |
| 37 | New Hope Rescue INC | Human Services | $211K | $44K |
| 38 | Bonnie Plants Foundation | Food, Agriculture & Nutrition | $200K | $8K |
| 39 | Auburn Area Community Theatre | Arts, Culture & Humanities | $164K | $123K |
| 40 | Museum of East Alabama | Arts, Culture & Humanities | $160K | $631K |
| 41 | Lee County Literacy Coalition | Unclassified | $143K | $23K |
| 42 | Opelika Main Street INC | Community Improvement & Capacity Building | $143K | $588K |
| 43 | Opelika Pickleball Club | Recreation & Sports | $136K | $62K |
| 44 | Lee County Farmers Federation | Unclassified | $134K | $629K |
| 45 | American Legion | Unclassified | $131K | $223K |
| 46 | Opelika Kiwanis Foundation INC | Philanthropy, Voluntarism & Grantmaking | $97K | $137K |
| 47 | The Curtis House | Philanthropy, Voluntarism & Grantmaking | $95K | $611 |
| 48 | Opelika Community Theatre INC | Arts, Culture & Humanities | $90K | $2K |
| 49 | One Voice Shelter Coalition | Housing & Shelter | $90K | $450K |
| 50 | Sara Schwarzauer Jesus Loves You Family Foundation | Philanthropy, Voluntarism & Grantmaking | $86K | $63K |
| 51 | Exodus Ranch | Housing & Shelter | $82K | $263K |
| 52 | Alabama Sports Officials Foundation INC | Unclassified | $78K | $248K |
| 53 | Benevolent & Protective Order of Elks of the USA | Unclassified | $78K | $2.1M |
| 54 | International Association of Lions Clubs | Unclassified | $73K | $16K |
| 55 | Alabama Gamma of Pi Beta Phi House Association Incorporated | Unclassified | $73K | $393K |
| 56 | The@ann Washington Hillyer Foundation | Philanthropy, Voluntarism & Grantmaking | $73K | $118K |
| 57 | Anz Family Foundation | Unclassified | $72K | $76K |
| 58 | East Alabama Group Home INC | Unclassified | $71K | $157K |
| 59 | Alabama Society of Oral and Maxillofacial Surgeons INC | Community Improvement & Capacity Building | $69K | $149K |
| 60 | Opelika Rotary Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $65K | $155K |
| 61 | Council on Aviation Accreditation INC | Public & Societal Benefit | $62K | $139K |
| 62 | Keep Opelika Beautiful INC | Environment | $56K | $87K |
| 63 | J W Darden Foundation | Arts, Culture & Humanities | $54K | $215K |
| 64 | Faith Foundation of Alabama INC | Philanthropy, Voluntarism & Grantmaking | $53K | $11K |
| 65 | Mission Equip | Religion-Related | $51K | $4K |
| 66 | Community Foundation of Eastalabama INC | Philanthropy, Voluntarism & Grantmaking | $49K | $11K |
| 67 | Henry J Stern Foundation | Philanthropy, Voluntarism & Grantmaking | $43K | $1.5M |
| 68 | Auburn Opelika Korean School | Education | $27K | $6K |
| 69 | National Village Ladies Club INC | Recreation & Sports | $22K | $3K |
| 70 | Created with Purpose | Human Services | $17K | $9K |
| 71 | Hashem Ministries | Religion-Related | $15K | $14K |
| 72 | Andy Kelley Ministries Church of the Living Gospel | Religion-Related | $14K | $2K |
| 73 | Internal Medicine Associates Scholarship Fund | Unclassified | $11K | $177K |
| 74 | Vital Wildlife Foundation INC | Animal-Related | $10K | $1K |
| 75 | Victorian Front Porch Christmas Tour of Opelika | Arts, Culture & Humanities | $8K | $6K |
| 76 | National Exchange Club | Unclassified | $4K | $15K |
| 77 | East Alabama Sports Outreach | Education | $2K | $942 |
| 78 | Journeys Heart | Human Services | $1K | $66 |
| 79 | Lee County Cemetery Preservation Commission INC | Mutual & Membership Benefit | $0 | $0 |
| 80 | Southside Church of Christ Centers INC | Religion-Related | $0 | $0 |
| 81 | Ryan John Ministries | Religion-Related | $0 | $0 |
| 82 | Fraternal Order of Police | Unclassified | $0 | $0 |
| 83 | Breaking the Cycle INC | Human Services | $0 | $0 |
| 84 | Dream Day Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 85 | Holy Life Ministries INC | Food, Agriculture & Nutrition | $0 | $0 |
| 86 | Covenant Smiles Dental Care & Labs INC | Unclassified | $0 | $0 |
| 87 | Gurudwara Singh Sabha | Religion-Related | $0 | $0 |
| 88 | Auburn Opelika Parkinsons Disease Support Group INC | Education | $0 | $0 |
| 89 | 1 Accord Social Savings Club | Human Services | $0 | $0 |
| 90 | Hopewell Cemetery Association INC | Mutual & Membership Benefit | $0 | $0 |
| 91 | Victory Churc H | Religion-Related | $0 | $0 |
| 92 | Redeeming Love Help Center | Religion-Related | $0 | $0 |
| 93 | Cheryl Comer Ministries INC | Unclassified | $0 | $0 |
| 94 | Campus Church INC | Religion-Related | $0 | $0 |
| 95 | Miracle League of East Alabama INC | Recreation & Sports | $0 | $0 |
| 96 | Southern Union State Community College Mu Alpha Theta | Unclassified | $0 | $0 |
| 97 | American Legion Auxiliary | Unclassified | $0 | $0 |
| 98 | Global Impact Church | Religion-Related | $0 | $0 |
| 99 | Hope Harvest | Food, Agriculture & Nutrition | $0 | $0 |
| 100 | Rus Roots Foundation | Recreation & Sports | $0 | $0 |