| 1 | Mass General Brigham Incorporated and Affiliates Group RTN Somerville, MA | $23.5B | $28.3B |
| 2 | Fidelity Investments Charitable Gift Fund Boston, MA | $19.0B | $66.8B |
| 3 | President and Fellows of Harvard College Cambridge, MA | $7.7B | $74.4B |
| 4 | Massachusetts Institute of Technology Cambridge, MA | $5.9B | $39.9B |
| 5 | Boston Medical Center Health Plan INC Charlestown, MA | $5.2B | $1.7B |
| 6 | Umass Memorial Health Care INC Worcester, MA | $4.2B | $3.2B |
| 7 | Dana-farber Cancer Institute Boston, MA | $3.5B | $5.3B |
| 8 | Childrens Hospital Corporation Boston, MA | $3.2B | $8.9B |
| 9 | Beth Israel Deaconess Medical Center INC Boston, MA | $3.1B | $3.8B |
| 10 | Northeastern University Boston, MA | $3.0B | $6.4B |
| 11 | Commonwealth Care Alliance INC Boston, MA | $2.8B | $538.4M |
| 12 | Tufts Health Public Plans INC Canton, MA | $2.6B | $988.4M |
| 13 | Tufts Associated Health Maintenance Organization INC Canton, MA | $2.6B | $945.4M |
| 14 | The Mitre Corporation Bedford, MA | $2.5B | $1.2B |
| 15 | Harvard Pilgrim Health Care INC Boston, MA | $2.5B | $1.1B |
| 16 | Mass General Brigham Health Plan INC Somerville, MA | $2.2B | $741.0M |
| 17 | Tempus Unlimited INC Stoughton, MA | $2.1B | $223.5M |
| 18 | Harvard Management Private Equity Corporation Boston, MA | $2.1B | $49.2B |
| 19 | Mass General Brigham Incorporated Somerville, MA | $1.9B | $9.8B |
| 20 | Fallon Community Health Plan INC Worcester, MA | $1.8B | $671.1M |
| 21 | Baystate Medical Center INC Springfield, MA | $1.8B | $1.7B |
| 22 | Bank of America Charitable Gift Fund Boston, MA | $1.7B | $5.1B |
| 23 | Boston College Trustees Chestnut Hill, MA | $1.6B | $6.9B |
| 24 | Trustees of Tufts College Medford, MA | $1.4B | $4.7B |
| 25 | Tufts Medical Center Parent INC Boston, MA | $1.4B | $965.4M |
| 26 | Northrop Grumman Veba Master Trust I Quincy, MA | $1.3B | $249.5M |
| 27 | Lahey Clinic Hospital INC Burlington, MA | $1.2B | $627.0M |
| 28 | Southcoast Hospitals Group INC New Bedford, MA | $1.2B | $1.2B |
| 29 | Cape Cod Healthcare INC Hyannis, MA | $1.1B | $1.3B |
| 30 | The Johnson & Johnson Voluntary Employee Benefit Trust Quincy, MA | $1.1B | $63.5M |
| 31 | Health New England & Subsidiaries Springfield, MA | $995.6M | $294.1M |
| 32 | South Shore Hospital INC S Weymouth, MA | $895.9M | $689.6M |
| 33 | Mgb Pooled Holdings LLC Somerville, MA | $892.1M | $16.2B |
| 34 | Beth Israel Lahey Health INC Hcsr Cambridge, MA | $876.1M | $545.8M |
| 35 | Charles Stark Draper Laboratory INC Cambridge, MA | $871.1M | $817.0M |
| 36 | Broad Institute INC Cambridge, MA | $831.1M | $2.9B |
| 37 | Berkshire Medical Center INC Pittsfield, MA | $757.5M | $831.9M |
| 38 | Harvard Medical Faculty Phys at Beth Israel Deaconess Med Ctr INC Boston, MA | $714.6M | $400.8M |
| 39 | Umass Memorial Health Care INC Worcester, MA | $692.5M | $2.3B |
| 40 | The Lowell General Hospital Lowell, MA | $605.3M | $399.9M |
| 41 | Northeast Hospital Corporation Beverly, MA | $537.4M | $517.3M |
| 42 | Brandeis University Waltham, MA | $502.5M | $1.8B |
| 43 | Worcester Polytechnic Institute Worcester, MA | $490.8M | $1.3B |
| 44 | Harvard Pilgrim Health Care of New England INC Canton, MA | $466.2M | $146.8M |
| 45 | Seven Hills Foundation INC Worcester, MA | $461.2M | $303.3M |
| 46 | Childrens Hospital Pediatric Associates INC Boston, MA | $454.9M | $675.0M |
| 47 | Williams College Williamstown, MA | $447.9M | $5.1B |
| 48 | Elderhostel INC Boston, MA | $446.0M | $384.0M |
| 49 | Baystate Medical Practices INC Springfield, MA | $444.9M | $99.1M |
| 50 | Berklee College of Music INC Boston, MA | $441.4M | $953.1M |