| 1 | A Mainehealth Hcsr Portland | E | $4.9B | $4.1B | $4.2B |
| 2 | Eastern Maine Healthcare Systems Brewer | E | $1.1B | $1.1B | $931.4M |
| 3 | Jackson Laboratory Bar Harbor | H | $821.2M | $652.5M | $1.6B |
| 4 | Mainegeneral Health Augusta | Z | $802.7M | $743.2M | $682.2M |
| 5 | Bowdoin College Brunswick | B | $788.7M | $369.8M | $3.2B |
| 6 | Puffin Bay Foundation Biddeford | T | $784.2M | $0 | $679.0M |
| 7 | Martins Point Generations Advantage INC Portland | E | $763.4M | $745.8M | $221.8M |
| 8 | Maine Community Foundation INC Ellsworth | T | $660.3M | $138.8M | $807.6M |
| 9 | Maine Education Association Benefits Trust Augusta | Z | $632.1M | $591.8M | $170.0M |
| 10 | Martins Point Health Care INC Portland | E | $596.6M | $550.1M | $575.9M |
| 11 | Eastern Maine Healthcare Systems Brewer | Z | $546.5M | $440.7M | $929.3M |
| 12 | President & Trustees of Colby College Waterville | B | $526.2M | $379.6M | $2.4B |
| 13 | Central Maine Medical Center Lewiston | E | $516.9M | $513.4M | $265.3M |
| 14 | University of New England Biddeford | B | $394.8M | $303.4M | $788.8M |
| 15 | Mercy Hospital Portland | E | $329.2M | $328.2M | $259.7M |
| 16 | Maine Community Health Options New Gloucestr | Y | $303.8M | $303.8M | $124.3M |
| 17 | President and Trustees of Bates College Lewiston | B | $253.0M | $192.8M | $887.4M |
| 18 | St. Joseph Hospital Bangor | E | $238.2M | $238.2M | $86.5M |
| 19 | St. Marys Regional Medical Center Lewiston | E | $236.2M | $236.2M | $135.7M |
| 20 | York Hospital York | E | $217.6M | $205.4M | $117.1M |
| 21 | Employees of Municipal & Other Pub- Lic Employers of Me Health Ins TR Augusta | Z | $213.4M | $213.4M | $120.4M |
| 22 | Harold Alfond Foundation Portland | T | $191.7M | $0 | $1.0B |
| 23 | Kahle-austin Family Foundation Biddeford | T | $181.1M | $0 | $118.7M |
| 24 | Maine Guaranteed Access Reinsurance Association Portland | E | $176.5M | $79.8M | $87.0M |
| 25 | Eastern Maine Healthcare Systems Presque Isle | E | $168.7M | $168.5M | $81.4M |
| 26 | Redington-fairview General Hospital Skowhegan | E | $158.9M | $158.9M | $148.6M |
| 27 | Maine Health Access Foundation INC Augusta | E | $142.1M | $0 | $154.4M |
| 28 | New England Life Care INC Scarborough | Z | $135.2M | $135.2M | $62.1M |
| 29 | Kahle-austin Foundation Biddeford | T | $129.4M | $0 | $161.8M |
| 30 | Maine Veterans Home Augusta | E | $123.6M | $106.7M | $172.6M |
| 31 | Mount Desert Island Hospital Bar Harbor | E | $120.0M | $114.7M | $106.0M |
| 32 | Maine Coast Regional Health Facili DBA Northern Light Maine Coast Hos Ellsworth | E | $117.8M | $117.8M | $80.8M |
| 33 | Husson University Bangor | B | $113.5M | $86.2M | $152.9M |
| 34 | University of Maine Foundation Orono | B | $112.3M | $60.4M | $458.3M |
| 35 | Nordx Scarborough | E | $109.7M | $106.8M | $46.7M |
| 36 | Good Sheperd Food Bank Auburn | K | $109.6M | $104.5M | $44.8M |
| 37 | Unity Environmental University New Gloucester | B | $105.4M | $86.7M | $107.2M |
| 38 | Penobscot Community Health Center Bangor | E | $104.2M | $102.9M | $79.1M |
| 39 | Blue Horizons Foundation Gorham | T | $101.0M | $0 | $239.7M |
| 40 | Spurwink Services Incorporated Portland | Z | $98.0M | $96.4M | $51.6M |
| 41 | Central Maine Healthcare Corporation Lewiston | E | $92.7M | $66.5M | $141.8M |
| 42 | Eastern Maine Healthcare Systems Bangor | E | $87.9M | $87.9M | $115.1M |
| 43 | Androscoggin Home Health Services INC Lewiston | E | $81.2M | $58.7M | $42.8M |
| 44 | John F Murphy Homes INC Auburn | P | $79.2M | $79.2M | $94.8M |
| 45 | Eastern Maine Healthcare Systems Waterville | E | $76.9M | $76.9M | $49.2M |
| 46 | Eastern Maine Healthcare Systems Dovr Foxcroft | E | $73.7M | $73.7M | $48.8M |
| 47 | Northern Maine Medical Center Fort Kent | E | $70.6M | $70.6M | $105.4M |
| 48 | John T Gorman Foundation Portland | T | $70.0M | $0 | $223.5M |
| 49 | Sweetser Saco | P | $67.1M | $54.7M | $52.1M |
| 50 | Penquis C a P INC Bangor | P | $66.6M | $66.5M | $52.2M |