| 1 | Ochsner Clinic Foundation New Orleans | E | $9.3B | $6.0B | $6.6B |
| 2 | The Administrators of the Tulane Educational Fund New Orleans | B | $2.1B | $1.8B | $4.3B |
| 3 | Our Lady of the Lake Hospital INC Baton Rouge | E | $2.0B | $1.9B | $3.2B |
| 4 | Louisiana Childrens Medical Center New Orleans | E | $1.6B | $1.6B | $4.3B |
| 5 | Willis-knighton Medical Center Shreveport | E | $1.5B | $1.5B | $3.1B |
| 6 | Childrens Hospital INC New Orleans | E | $1.3B | $737.3M | $2.5B |
| 7 | Ochsner Lsu Health System of North Louisiana Shreveport | E | $1.1B | $1.0B | $985.4M |
| 8 | Womans Hospital Foundation Baton Rouge | E | $897.5M | $897.5M | $1.2B |
| 9 | University Medical Center Management Corporaton New Orleans | G | $792.9M | $792.9M | $502.5M |
| 10 | Lafayette General Medical Center INC Lafayette | E | $746.3M | $734.9M | $750.6M |
| 11 | Baton Rouge General Medical Center Baton Rouge | E | $711.6M | $688.7M | $532.8M |
| 12 | Our Lady of Lourdes Regional Medical Center INC Baton Rouge | E | $631.8M | $628.4M | $804.9M |
| 13 | Southwest Louisiana Hospital Association INC Lake Charles | E | $534.6M | $534.4M | $352.6M |
| 14 | Franciscan Missionaries of Our Lady Health System INC Baton Rouge | E | $489.5M | $369.0M | $3.1B |
| 15 | St. Francis Medical Center INC Baton Rouge | E | $445.8M | $433.2M | $317.5M |
| 16 | Louisiana Insurance Guaranty Association Baton Rouge | Z | $437.6M | $222.9M | $383.7M |
| 17 | Christus Health Central Louisiana Alexandria | E | $426.7M | $426.7M | $180.7M |
| 18 | Xavier University of Louisiana New Orleans | B | $424.2M | $158.7M | $523.6M |
| 19 | Touro Infirmary New Orleans | E | $379.1M | $367.3M | $383.8M |
| 20 | Provident Resources Group INC Baton Rouge | E | $356.1M | $356.1M | $4.1B |
| 21 | Thibodaux Regional Health System INC Thibodaux | E | $348.4M | $348.2M | $533.1M |
| 22 | Christus Health Northern Louisiana Shreveport | E | $334.1M | $333.6M | $223.6M |
| 23 | Loyola University New Orleans | B | $316.7M | $216.8M | $708.9M |
| 24 | Lafayette General Health System INC Lafayette | E | $307.0M | $301.4M | $1.2B |
| 25 | Christus Health Southwestern Louisiana Lake Charles | E | $306.3M | $306.2M | $170.5M |
| 26 | Southwest Louisiana Electric Lafayette | Z | $304.1M | $303.8M | $555.8M |
| 27 | The Greater New Orleans Foundation New Orleans | T | $291.3M | $67.6M | $513.0M |
| 28 | Dixie Electric Membership Corporation Baton Rouge | Z | $274.5M | $274.5M | $733.8M |
| 29 | Mary Bird Perkins Cancer Center Baton Rouge | G | $229.7M | $229.6M | $141.1M |
| 30 | Kemper and Leila Williams Foundation New Orleans | T | $226.0M | $0 | $470.1M |
| 31 | Commcare Corporation Mandeville | E | $220.4M | $220.3M | $235.1M |
| 32 | Tiger Athletic Foundation Baton Rouge | B | $212.8M | $123.9M | $497.1M |
| 33 | Lsu Health Sciences Center - Shreveport Faculty Group Practice Shreveport | F | $204.8M | $204.8M | $326.1M |
| 34 | L S U Foundation Baton Rouge | B | $203.1M | $81.9M | $921.9M |
| 35 | University Hospital & Clinics INC Lafayette | E | $202.4M | $189.6M | $104.0M |
| 36 | Louisiana State University of Medicine in New Orleans New Orleans | E | $177.7M | $161.3M | $120.9M |
| 37 | Beauregard Electric Cooperative INC Deridder | Z | $163.0M | $163.0M | $259.8M |
| 38 | General Health System Baton Rouge | E | $158.7M | $138.2M | $269.4M |
| 39 | The Alta and John Franks Foundation Shreveport | Z | $153.6M | $0 | $220.4M |
| 40 | Methodist Health System Foundation INC Slidell | Z | $134.6M | $3.8M | $74.0M |
| 41 | Second Harvest Food Bank of Greater New Orleans and Acadiana New Orleans | K | $124.8M | $101.0M | $89.9M |
| 42 | Washington-st Tammany Electric Cooperative INC 1570 Franklinton | Z | $124.8M | $124.8M | $292.6M |
| 43 | Kipp New Orleans INC New Orleans | B | $117.9M | $117.9M | $53.0M |
| 44 | Community Foundation of Acadiana Lafayette | T | $111.7M | $31.7M | $183.5M |
| 45 | National World War II Museum INC New Orleans | A | $103.3M | $100.2M | $426.3M |
| 46 | Louisiana Sheriffs Association Group Benefits TR Baton Rouge | Y | $100.3M | $100.3M | $30.3M |
| 47 | Inspirenola Charter Schools New Orleans | B | $93.9M | $93.9M | $46.2M |
| 48 | Goldring Family Foundation Metairie | T | $88.6M | $0 | $199.2M |
| 49 | State Chartered Credit Unions in Louisiana Baton Rouge | Z | $88.5M | $88.5M | $722.6M |
| 50 | New Orleans Jazz & Heritage Foundation INC New Orleans | A | $84.8M | $73.7M | $54.8M |