| 1 | Air Line Pilots Association International | Unclassified | $974.9M | $663.2M |
| 2 | Bedford Falls Foundation | Philanthropy, Voluntarism & Grantmaking | $172.1M | $176.5M |
| 3 | Weissberg Foundation | Unclassified | $138.8M | $223.0M |
| 4 | Potomac School | Education | $113.3M | $246.4M |
| 5 | Capital One Foundation INC | Education | $110.1M | $154.3M |
| 6 | Fringe Benefit Plan for Service Contract Act Employees of Maximus | Mutual & Membership Benefit | $75.9M | $35.0M |
| 7 | Culp Family Foundation | Philanthropy, Voluntarism & Grantmaking | $70.0M | $35.1M |
| 8 | Andeco Institute | Public & Societal Benefit | $69.1M | $12.1M |
| 9 | Alpa Retiree Health Plan for Jetblue Pilots Veba Tr | Mutual & Membership Benefit | $55.3M | $70.9M |
| 10 | Amt-the Association for Manufacturing Technology | Unclassified | $53.9M | $56.3M |
| 11 | Langley School INC | Education | $50.7M | $90.4M |
| 12 | Madeira School INC | Education | $37.8M | $208.0M |
| 13 | Fedex Pilots Post-medicare Retiree Premium Reimbursement Plan | Mutual & Membership Benefit | $35.6M | $198.2M |
| 14 | Air Line Pilots Association Pilot Welfare Benefit Plan | Unclassified | $33.7M | $81.2M |
| 15 | Kohn Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $31.2M | $50.5M |
| 16 | Bbb National Programs INC | Unclassified | $30.2M | $31.7M |
| 17 | Hawaiian Pilots Post Medicare Health Plan Veba Trust | Mutual & Membership Benefit | $30.0M | $169.7M |
| 18 | Volgenau Foundation | Environment | $29.4M | $166.2M |
| 19 | International Copper Association Ltd | Unclassified | $29.2M | $15.4M |
| 20 | The J127 Education Foundation | Education | $28.5M | $30.0M |
| 21 | Food Allergy Research & Education INC | Food, Agriculture & Nutrition | $27.4M | $33.2M |
| 22 | Muslim Aid America | Public Safety, Disaster Preparedness & Relief | $27.1M | $5.5M |
| 23 | National Science Teaching Association | Education | $22.3M | $25.5M |
| 24 | International Foodservice Distributors Association INC | Community Improvement & Capacity Building | $21.9M | $24.3M |
| 25 | The Merrill Foundation INC | Unclassified | $19.4M | $42.2M |
| 26 | National Education Foundation | Unclassified | $19.2M | $63.1M |
| 27 | Joshua Fund | Religion-Related | $19.1M | $7.2M |
| 28 | International Associationn of Fire Chiefs INC | Public Safety, Disaster Preparedness & Relief | $16.8M | $14.5M |
| 29 | Air Line Pilots Association | Unclassified | $15.3M | $53.4M |
| 30 | Geoscienceworld | Science & Technology | $13.6M | $8.8M |
| 31 | Susan Lynde Duval Phipps Foundation INC | Philanthropy, Voluntarism & Grantmaking | $11.9M | $13.6M |
| 32 | Superior Living Foundation INC | Housing & Shelter | $11.6M | $31.9M |
| 33 | Skillsource Group INC | Philanthropy, Voluntarism & Grantmaking | $10.8M | $4.2M |
| 34 | Willows International | Health Care | $10.7M | $4.5M |
| 35 | Responsible Online Gaming Association | Recreation & Sports | $10.5M | $7.6M |
| 36 | Sharifi Family Foundation | Philanthropy, Voluntarism & Grantmaking | $10.0M | $10.0M |
| 37 | Chamber of Progress | Community Improvement & Capacity Building | $9.7M | $14.3M |
| 38 | Advance Democracy INC | International, Foreign Affairs & National Security | $8.6M | $7.7M |
| 39 | Center Forward | Public & Societal Benefit | $8.3M | $5.9M |
| 40 | Zcash Foundation | Science & Technology | $8.2M | $23.4M |
| 41 | American Association of Tissue Banks INC | Unclassified | $7.7M | $8.5M |
| 42 | Hilton Effect Foundation | Philanthropy, Voluntarism & Grantmaking | $7.6M | $5.1M |
| 43 | The Albert and Linda Rosecan Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $7.5M | $7.2M |
| 44 | Mitre Corporation Employee Benefits Trust | Unclassified | $7.4M | $64.3M |
| 45 | Strategic Capacity Group INC | Education | $7.4M | $1.5M |
| 46 | Compressed Gas Association INC | Unclassified | $6.4M | $11.0M |
| 47 | Copper Development Association INC | Unclassified | $6.2M | $5.2M |
| 48 | Montessori School of McLean | Education | $5.6M | $17.2M |
| 49 | Country Day School | Unclassified | $5.6M | $14.2M |
| 50 | Center for American Ideas | Public & Societal Benefit | $5.4M | $133K |
| 51 | Kettler Health Care Plan | Mutual & Membership Benefit | $5.3M | $1.7M |
| 52 | Long and Kimmy Nguyen Family Foundation | Philanthropy, Voluntarism & Grantmaking | $5.3M | $18.6M |
| 53 | Society of Vertebrate Paleontology | Unclassified | $5.2M | $5.8M |
| 54 | Brooksfield School INC | Unclassified | $4.9M | $3.0M |
| 55 | Christian Alliance for Orphans | Human Services | $4.9M | $6.0M |
| 56 | Citizens Behind the Badge | Crime & Legal-Related | $4.8M | $197K |
| 57 | Hospitality Sales and Marketing Association International INC | Unclassified | $4.7M | $1.9M |
| 58 | Ortner Family Foundation | Philanthropy, Voluntarism & Grantmaking | $4.7M | $19.5M |
| 59 | Friends of Fafg INC | International, Foreign Affairs & National Security | $4.5M | $154K |
| 60 | Association of Organ Procurement Organizations | Community Improvement & Capacity Building | $4.5M | $6.2M |
| 61 | Lewinsville Retirement Residence | Housing & Shelter | $4.3M | $21.8M |
| 62 | Center for Excellence in Education | Science & Technology | $4.2M | $11.9M |
| 63 | Board of Registered Polysomnographic Technologists | Community Improvement & Capacity Building | $4.2M | $2.8M |
| 64 | A Public Voice INC | Public & Societal Benefit | $3.9M | $943K |
| 65 | Maximus Foundation | Philanthropy, Voluntarism & Grantmaking | $3.8M | $1.4M |
| 66 | Food Production Solutions Association | Community Improvement & Capacity Building | $3.6M | $16.7M |
| 67 | The Matthew Korn and Cynthia Miller Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.6M | $4.3M |
| 68 | McLean Youth Soccer Association | Recreation & Sports | $3.6M | $5.1M |
| 69 | Trehan Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.5M | $13.9M |
| 70 | Academic Pediatric Association | Diseases, Disorders & Medical Disciplines | $3.4M | $2.0M |
| 71 | Halprin Family Foundation a | Philanthropy, Voluntarism & Grantmaking | $3.4M | $2.3M |
| 72 | Lee and Juliet Folger Fund | Unclassified | $3.3M | $7.6M |
| 73 | Resolve Incorporated | Health Care | $3.3M | $1.7M |
| 74 | Walter and Jean Boek Global Autoimmune Institute | Unclassified | $3.2M | $15.5M |
| 75 | Tuckahoe Recreation Club INC | Unclassified | $3.2M | $4.0M |
| 76 | Perlin Family Foundation | Philanthropy, Voluntarism & Grantmaking | $3.1M | $6.2M |
| 77 | Pediatric Endocrine Society | Medical Research | $3.1M | $8.5M |
| 78 | Association of Pediatrics Program Directors | Education | $3.0M | $2.8M |
| 79 | Board for Global Ehs Credentialing | Unclassified | $3.0M | $4.2M |
| 80 | Professional Tennis Players Association | Civil Rights, Social Action & Advocacy | $3.0M | $85K |
| 81 | Sarnoff Cardiovascular Research Foundation INC | Diseases, Disorders & Medical Disciplines | $2.9M | $50.9M |
| 82 | The Incentive Research Foundation | Employment | $2.7M | $2.1M |
| 83 | Association of Pediatric Hematology Oncology Nurses INC | Diseases, Disorders & Medical Disciplines | $2.7M | $1.7M |
| 84 | Merton College Charitable Corporation | International, Foreign Affairs & National Security | $2.7M | $5.2M |
| 85 | Plumbing Manufacturers International Nfp | Unclassified | $2.7M | $3.1M |
| 86 | Employee Activity Association INC | Unclassified | $2.6M | $869K |
| 87 | America World Adoption Association | Human Services | $2.6M | $3.1M |
| 88 | Mitchell Foundation | Philanthropy, Voluntarism & Grantmaking | $2.6M | $5.5M |
| 89 | Institute for Responsible Citizenship INC | Education | $2.5M | $3.8M |
| 90 | McLean Project for the Arts INC | Arts, Culture & Humanities | $2.4M | $1.8M |
| 91 | Springboard 2000 Enterprises INC | Employment | $2.3M | $1.3M |
| 92 | American Association of Political Consultants INC | Unclassified | $2.3M | $1.7M |
| 93 | U S Apple Association | Unclassified | $2.3M | $3.1M |
| 94 | Constellation Schools Lorain Community Elementary | Education | $2.2M | $4.2M |
| 95 | Ambleside School | Education | $2.1M | $1.9M |
| 96 | David H and Suzanne D Hillman Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.9M | $2.8M |
| 97 | Burchfield Family Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $1.9M | $4.1M |
| 98 | Westgate Child Center Corporation | Education | $1.8M | $3.6M |
| 99 | Nywici Foundation INC | Education | $1.8M | $389K |
| 100 | Academy of Pelvic Health Physical Therapy | Unclassified | $1.8M | $2.8M |