| 1 | Skills USA INC | Employment | $33.1M | $15.3M |
| 2 | National Institute for Automotive Service Exellence | Unclassified | $27.8M | $26.3M |
| 3 | Loudoun Community Health Center | Health Care | $15.1M | $18.8M |
| 4 | Loudoun Country Day School INC | Education | $12.3M | $38.8M |
| 5 | American Roentgen Ray Society | Diseases, Disorders & Medical Disciplines | $11.9M | $36.6M |
| 6 | American Wood Council | Community Improvement & Capacity Building | $9.4M | $6.8M |
| 7 | Loudoun Hunger Relief | Religion-Related | $8.5M | $8.7M |
| 8 | Ocean Visions INC | Science & Technology | $8.3M | $9.9M |
| 9 | Loudoun Youth Soccer Association | Recreation & Sports | $7.6M | $8.4M |
| 10 | Community Foundation for Loudoun and Northern Fauquier Counties | Philanthropy, Voluntarism & Grantmaking | $7.5M | $13.3M |
| 11 | The Arc of Loudoun | Human Services | $7.1M | $1.1M |
| 12 | Every Citizen Has Opportunities INC | Employment | $6.6M | $4.0M |
| 13 | Westmoreland Davis Memorial Foundation INC | Unclassified | $5.2M | $19.7M |
| 14 | Society for Imaging Informatics in Medicine-siim | Diseases, Disorders & Medical Disciplines | $5.1M | $8.8M |
| 15 | Spookstock Foundation | Philanthropy, Voluntarism & Grantmaking | $5.1M | $806K |
| 16 | Composite Panel Association | Unclassified | $4.9M | $4.9M |
| 17 | Data Center Coalition | Community Improvement & Capacity Building | $4.7M | $1.3M |
| 18 | Loudoun Convention & Visitors Association INC | Unclassified | $4.5M | $3.8M |
| 19 | United States Eventing Association | Arts, Culture & Humanities | $4.2M | $2.4M |
| 20 | Loudoun Citizens for Social Justice INC | Human Services | $4.1M | $5.8M |
| 21 | Providence Academy | Education | $4.0M | $3.3M |
| 22 | Evergreen Christian School | Education | $3.8M | $2.1M |
| 23 | Alethia Labs INC | Education | $3.8M | $356K |
| 24 | Ase Education Foundation | Unclassified | $3.2M | $1.9M |
| 25 | The International Assoc of Computer Investigative Specialists INC | Unclassified | $3.2M | $3.7M |
| 26 | Habitat for Humanity International | Unclassified | $3.0M | $2.1M |
| 27 | Loudoun Cares | Human Services | $2.8M | $1.5M |
| 28 | International Society for Computational Biology INC | Science & Technology | $2.5M | $3.5M |
| 29 | Operator Relief Fund INC | Mental Health & Crisis Intervention | $2.4M | $791K |
| 30 | Cure Jm Foundation | Diseases, Disorders & Medical Disciplines | $2.3M | $2.6M |
| 31 | Society for the Study of Reproduction INC | Education | $2.3M | $8.3M |
| 32 | Greenway Educational Initiative INC | Religion-Related | $2.3M | $160K |
| 33 | Margaret Paxton Memorial for Convalesctent Children | Philanthropy, Voluntarism & Grantmaking | $2.0M | $9.4M |
| 34 | Leesburg Lodge No 1041 Loyal Order of the Moose | Unclassified | $1.8M | $1.8M |
| 35 | Journey Through Hallowed Ground Partnership | Arts, Culture & Humanities | $1.8M | $812K |
| 36 | Chamber of Commerce Loudoun County | Unclassified | $1.8M | $2.1M |
| 37 | Leesburg Volunteer Fire Company | Public Safety, Disaster Preparedness & Relief | $1.7M | $10.7M |
| 38 | Mobile Hope Association | Youth Development | $1.7M | $3.8M |
| 39 | Nonprofit Risk Management Center | Community Improvement & Capacity Building | $1.4M | $1.6M |
| 40 | Blue Sea Philanthropy USA | Philanthropy, Voluntarism & Grantmaking | $1.3M | $414K |
| 41 | Loudoun County Volunteer Rescue Squad INC | Unclassified | $1.2M | $7.9M |
| 42 | Sharon Virts Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $3.0M |
| 43 | Catoctin Foundation INC | Health Care | $1.2M | $1.3M |
| 44 | Charles and Marion Stone Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.1M | $1.1M |
| 45 | Loudoun Community Media | Arts, Culture & Humanities | $1.1M | $196K |
| 46 | Allder Montessori School | Education | $1.0M | $785K |
| 47 | American Society of Health Economists | Health Care | $970K | $937K |
| 48 | George C Marshall International Center INC | Arts, Culture & Humanities | $945K | $5.9M |
| 49 | Loudoun First Responders Foundation INC | Public Safety, Disaster Preparedness & Relief | $850K | $608K |
| 50 | Oatlands INC | Arts, Culture & Humanities | $825K | $197K |
| 51 | Trinity House Community | Religion-Related | $812K | $179K |
| 52 | Loudoun Serenity House | Housing & Shelter | $794K | $244K |
| 53 | Usea Foundation | Philanthropy, Voluntarism & Grantmaking | $792K | $3.0M |
| 54 | International Aerospace Womens Association | Community Improvement & Capacity Building | $771K | $902K |
| 55 | Management Association for Private Photogrammetric Surveyors | Unclassified | $719K | $468K |
| 56 | All Services for International Adoptees and Adoptive Families | Education | $711K | $535K |
| 57 | Pku Hope Foundation | Medical Research | $704K | $1.1M |
| 58 | National Tax Association Tax Institute of America | Unclassified | $697K | $1.1M |
| 59 | Rean Foundation | Philanthropy, Voluntarism & Grantmaking | $695K | $4.1M |
| 60 | Special Libraries Association | Education | $666K | $1.4M |
| 61 | Dulles Area Association of Realtors | Unclassified | $652K | $875K |
| 62 | Gregory Christian Conran and Marina Angel Amat Foundation | Philanthropy, Voluntarism & Grantmaking | $641K | $615K |
| 63 | Affordable Housing Investors Council | Unclassified | $634K | $671K |
| 64 | Union Cemetery | Unclassified | $630K | $3.5M |
| 65 | 7X24 Exchange International Greater Washington Dc Chapter INC | Community Improvement & Capacity Building | $626K | $170K |
| 66 | Natysin Family Foundation | Philanthropy, Voluntarism & Grantmaking | $621K | $1.8M |
| 67 | Rackham Foundation Limited | Philanthropy, Voluntarism & Grantmaking | $611K | $2.1M |
| 68 | Loudon Fair & Associates INC | Youth Development | $606K | $1.4M |
| 69 | Loudoun Education Association | Unclassified | $599K | $2.1M |
| 70 | Veterans Moving Forward INC | Human Services | $565K | $1.3M |
| 71 | Eastern Nursing Research Society | Arts, Culture & Humanities | $544K | $628K |
| 72 | Loudoun Volunteer Caregivers a Faith in Action Program | Human Services | $542K | $671K |
| 73 | McMunn Family Foundation | Philanthropy, Voluntarism & Grantmaking | $538K | $1.7M |
| 74 | Smith Family Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $500K | $2.0M |
| 75 | The Loudoun Symphony Association INC | Arts, Culture & Humanities | $500K | $174K |
| 76 | Loudoun Laurels | Arts, Culture & Humanities | $488K | $518K |
| 77 | Southern Nursing Research Society | Health Care | $481K | $766K |
| 78 | Bridle Paths | Health Care | $473K | $376K |
| 79 | D1 Sports & Athletics | Education | $471K | $164K |
| 80 | Loudoun Dulles Fop Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $466K | $186K |
| 81 | The Humane Society of Loudoun County | Animal-Related | $462K | $416K |
| 82 | Morven Park INC | Human Services | $445K | $455K |
| 83 | Willowcroft Foundation | Philanthropy, Voluntarism & Grantmaking | $435K | $2.0M |
| 84 | International Association of Fire Fighters | Unclassified | $428K | $466K |
| 85 | Loudoun Wildlife Conservancy | Animal-Related | $404K | $934K |
| 86 | Legacy Farms | Human Services | $396K | $156K |
| 87 | The O Shaughnessy Hurst Memorial Foundation INC | Unclassified | $383K | $9.1M |
| 88 | Loudoun Museum INC | Arts, Culture & Humanities | $377K | $480K |
| 89 | Virginia Wrestling Association INC | Recreation & Sports | $344K | $98K |
| 90 | Pensmore Foundation | Philanthropy, Voluntarism & Grantmaking | $336K | $8.5M |
| 91 | Meeting Professionals International | Community Improvement & Capacity Building | $331K | $340K |
| 92 | International Anal Neoplasia Society | Diseases, Disorders & Medical Disciplines | $312K | $477K |
| 93 | American Society of Pain Management Nurses | Health Care | $306K | $316K |
| 94 | 360 Veterans | Human Services | $301K | $289K |
| 95 | Family of Saint Sharbel USA | Religion-Related | $291K | $42K |
| 96 | Loudoun Islamic Center | Religion-Related | $290K | $761K |
| 97 | Surgical Infection Society | Diseases, Disorders & Medical Disciplines | $273K | $105K |
| 98 | Embark Center | Education | $273K | $280K |
| 99 | Makersmiths INC | Community Improvement & Capacity Building | $267K | $324K |
| 100 | Fraternal Order of Police | Unclassified | $264K | $26K |