| 1 | Christus Health | Health Care | $3.6B | $3.5B |
| 2 | The Big 12 Conference INC | Education | $493.8M | $73.6M |
| 3 | Boy Scouts of America | Youth Development | $416.3M | $837.4M |
| 4 | Ypo INC | Unclassified | $302.2M | $388.4M |
| 5 | American Athletic Conference | Unclassified | $147.7M | $119.1M |
| 6 | University of Dallas | Education | $113.3M | $192.9M |
| 7 | Mother Frances Hospital Jacksonville | Health Care | $103.2M | $29.6M |
| 8 | Careflite | Health Care | $90.1M | $102.3M |
| 9 | National Boy Scouts of America Foundation | Youth Development | $79.8M | $137.8M |
| 10 | Baitulmaal INC | International, Foreign Affairs & National Security | $77.4M | $15.1M |
| 11 | Promotional Products Association International | Unclassified | $70.5M | $28.6M |
| 12 | Avocados from Mexico | Community Improvement & Capacity Building | $63.0M | $13.0M |
| 13 | Southwest Airlines Pilots Association | Unclassified | $58.0M | $50.2M |
| 14 | Oneshare Health LLC | Health Care | $50.6M | $9.3M |
| 15 | American Association for Respiratory Care | Unclassified | $50.0M | $49.2M |
| 16 | Mothers Against Drunk Driving | Crime & Legal-Related | $49.3M | $20.3M |
| 17 | Christus Trinity Mother Frances Foundation | Unclassified | $48.9M | $98.6M |
| 18 | American College of Emergency Physicians | Unclassified | $42.6M | $45.6M |
| 19 | Las Colinas Association | Unclassified | $39.7M | $33.6M |
| 20 | The Khimji Foundation | Philanthropy, Voluntarism & Grantmaking | $34.6M | $67.7M |
| 21 | Christus Northeast Texas and Northern Louisiana Health System C | Religion-Related | $31.6M | $5.6M |
| 22 | Mercury One INC | International, Foreign Affairs & National Security | $29.9M | $39.7M |
| 23 | Ser-jobs for Progress National INC | Unclassified | $27.8M | $3.6M |
| 24 | Mother Frances Hospital-winnsboro | Health Care | $25.3M | $13.5M |
| 25 | Sumners Foundation | Crime & Legal-Related | $25.2M | $74.1M |
| 26 | Irving Healthcare Foundation | Health Care | $24.2M | $20.4M |
| 27 | Christus Health Strategic Growth | Health Care | $22.8M | $257.8M |
| 28 | Mobility Credit Union | Unclassified | $22.1M | $373.6M |
| 29 | Ltts Charter School INC | Education | $22.0M | $46.5M |
| 30 | Disaster Services Corporation - Society of St. Vincent de Paul USA | Public Safety, Disaster Preparedness & Relief | $14.0M | $3.6M |
| 31 | Southwest Airlines Pilots Mutual Aid Plan | Unclassified | $13.0M | $4.3M |
| 32 | Ability Connection Texas | Diseases, Disorders & Medical Disciplines | $12.8M | $8.4M |
| 33 | American Pecan Promotion Board | Community Improvement & Capacity Building | $11.8M | $13.1M |
| 34 | Invited Foundation | Philanthropy, Voluntarism & Grantmaking | $11.4M | $1.7M |
| 35 | Caris Foundation | Philanthropy, Voluntarism & Grantmaking | $11.2M | $16.8M |
| 36 | Amoud Foundation | Philanthropy, Voluntarism & Grantmaking | $11.1M | $12.1M |
| 37 | Yaqeen Endowment | Civil Rights, Social Action & Advocacy | $11.0M | $42.8M |
| 38 | Metrotex Association of Realtors INC | Community Improvement & Capacity Building | $9.8M | $48.6M |
| 39 | Saving Texas | Civil Rights, Social Action & Advocacy | $9.4M | $70K |
| 40 | Connex | Unclassified | $9.1M | $7.1M |
| 41 | Christus Connected Care Network | Human Services | $9.1M | $9.0M |
| 42 | Manara Academy INC | Education | $8.1M | $6.5M |
| 43 | International Association of Venue Managers INC | Unclassified | $8.1M | $6.5M |
| 44 | Itserve Alliance INC | Community Improvement & Capacity Building | $8.0M | $6.5M |
| 45 | American Concrete Pipe Association | Unclassified | $7.2M | $4.9M |
| 46 | Christus Health Gulf Coast | Health Care | $7.2M | $31.5M |
| 47 | Surti Lueva Patidar Samaj of Dfw | Human Services | $7.1M | $10.6M |
| 48 | Southwest Airlines Pilots Association Voluntary Employees | Mutual & Membership Benefit | $6.9M | $11.9M |
| 49 | National Football Foundation and College Hall of Fame INC | Unclassified | $6.4M | $13.8M |
| 50 | Epayresources | Unclassified | $6.3M | $14.0M |
| 51 | Chrest Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.3M | $37.8M |
| 52 | Nudge Foundation | International, Foreign Affairs & National Security | $6.0M | $17.8M |
| 53 | C H Wilkinson Physician Network | Unclassified | $5.8M | $1.2M |
| 54 | Plastics Pipe Institute INC | Community Improvement & Capacity Building | $5.6M | $4.3M |
| 55 | Khimji Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $5.6M | $18.6M |
| 56 | Valley Ranch Master Association INC | Unclassified | $5.5M | $3.3M |
| 57 | Kimberly-clark Foundation INC | Education | $5.1M | $1 |
| 58 | Trincare INC | Health Care | $5.0M | $820K |
| 59 | Ramesh and Kalpana Bhatia Familyfoundation | Philanthropy, Voluntarism & Grantmaking | $5.0M | $7.3M |
| 60 | Electric Energy INC Employee Benefit Fund for Bargaining Unit | Unclassified | $4.9M | $3.1M |
| 61 | Caris Foundation International | International, Foreign Affairs & National Security | $4.9M | $641K |
| 62 | Dallas-fort Worth Hospital Council Education and Research Foundation | Unclassified | $4.7M | $9.3M |
| 63 | Dallas Fort Worth Metropolitan New Car Dealers Association | Community Improvement & Capacity Building | $4.3M | $4.1M |
| 64 | Enlace Christian Television INC | Religion-Related | $4.2M | $3.3M |
| 65 | Irving Schools Foundation | Unclassified | $4.2M | $4.9M |
| 66 | Independent Electrical Contractors | Unclassified | $4.1M | $4.0M |
| 67 | Oak Grove Memorial Gardens | Unclassified | $4.1M | $6.9M |
| 68 | Greater Irving - Las Colinas Chamber of Commerce | Unclassified | $4.0M | $1.6M |
| 69 | Asha Partners | Religion-Related | $3.8M | $4.2M |
| 70 | Dallas-fort Worth Hospital Council | Unclassified | $3.7M | $12.5M |
| 71 | Fluor Foundation | Education | $3.4M | $1.3M |
| 72 | Uni-bell Pvc Pipe Association | Unclassified | $3.3M | $2.2M |
| 73 | Korean Central United Methodist Church of Dallas | Unclassified | $3.1M | $8.0M |
| 74 | Learning for Life | Youth Development | $3.1M | $5.9M |
| 75 | Curing Kids Cancer INC | Human Services | $3.1M | $676K |
| 76 | Highgate Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.9M | $6.5M |
| 77 | Radiant Stem Academy INC | Education | $2.9M | $525K |
| 78 | Irving Cares INC | Human Services | $2.7M | $329K |
| 79 | Nrj Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $2.5M | $1.9M |
| 80 | Emergency Medicine Foundation | Health Care | $2.4M | $10.4M |
| 81 | A Continuous Charity Foundation | Education | $2.4M | $5.9M |
| 82 | Dallas Stars Elite Hockey Club | Recreation & Sports | $2.3M | $82K |
| 83 | Bsa Endowment Master Tr | Youth Development | $2.2M | $52.0M |
| 84 | North Central Texas Womens Business Development Council INC | Civil Rights, Social Action & Advocacy | $2.0M | $2.7M |
| 85 | Christus Continuing Care | Unclassified | $1.8M | $20.5M |
| 86 | Rahbar Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.7M | $1.3M |
| 87 | Council of Emergency Medicine Residency Directors | Unclassified | $1.6M | $2.3M |
| 88 | Young Catholic Professionals | Religion-Related | $1.5M | $1.4M |
| 89 | Faustina Academy | Education | $1.5M | $1.6M |
| 90 | National Football Foundation and College Hall of Fame INC | Unclassified | $1.4M | $1.8M |
| 91 | Brent Woodall Foundation for Exceptional Children | Diseases, Disorders & Medical Disciplines | $1.4M | $92K |
| 92 | Greenspace Dallas | Environment | $1.3M | $1.4M |
| 93 | Rawdah Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $761K |
| 94 | Christus Health International | Health Care | $1.2M | $141.2M |
| 95 | Boy Scouts of America | Unclassified | $1.2M | $4.9M |
| 96 | Strategic Global Response | Human Services | $1.1M | $98K |
| 97 | Christ Center Church INC | Religion-Related | $1.1M | $0 |
| 98 | Nec Foundation of Americas | Unclassified | $1.1M | $12.1M |
| 99 | Helping Hands Medical Mission INC | Unclassified | $1.1M | $171K |
| 100 | Bionorthtexas Foundation | Medical Research | $1.1M | $418K |