| 1 | Michael & Susan Dell Foundation | Philanthropy, Voluntarism & Grantmaking | $6.6B | $7.8B |
| 2 | Texas Mutual Insurance Company | Unclassified | $5.5B | $8.6B |
| 3 | Southwest Key Programs INC | Human Services | $927.3M | $256.3M |
| 4 | Electric Reliability Council of Texas INC 10-10-90 | Public & Societal Benefit | $543.2M | $7.4B |
| 5 | Texas Essential Healthcare Partnerships Foundation | Health Care | $390.9M | $75.4M |
| 6 | Florida Essential Healthcare Partnerships Foundation INC | Health Care | $359.7M | $153.3M |
| 7 | Southern Health Care Alliance | Mental Health & Crisis Intervention | $318.8M | $197K |
| 8 | Charitable Assets Tr | Philanthropy, Voluntarism & Grantmaking | $281.6M | $205.5M |
| 9 | St. Edwards University | Education | $273.0M | $420.8M |
| 10 | Tml Multistate Intergovernmental Employee Benefits | Mutual & Membership Benefit | $252.4M | $108.2M |
| 11 | Central Texas Community Health Centers | Health Care | $245.7M | $84.6M |
| 12 | Professional Contract Services INC | Human Services | $232.8M | $209.9M |
| 13 | St. Davids Foundation | Health Care | $217.5M | $2.0B |
| 14 | Goodwill Industries of Central Texas | Employment | $207.1M | $178.2M |
| 15 | Austin Community Foundation | Philanthropy, Voluntarism & Grantmaking | $191.4M | $556.3M |
| 16 | Austin Transit Partnership Local Government Corporation | Public & Societal Benefit | $188.2M | $562.3M |
| 17 | Musk Foundation | Philanthropy, Voluntarism & Grantmaking | $168.2M | $463.0M |
| 18 | Central Texas Food Bank INC | Food, Agriculture & Nutrition | $149.4M | $114.6M |
| 19 | C2c Innovative Solutions INC | Health Care | $146.8M | $245.6M |
| 20 | Austin-travis County Mental Health and Mental Retardation Center | Mental Health & Crisis Intervention | $141.3M | $122.2M |
| 21 | The Foundation | Education | $138.3M | $269.9M |
| 22 | Lutheran Social Service of the South INC | Human Services | $133.1M | $75.8M |
| 23 | Texas Life Accident Health & Hosp Service Insurance Guaranty Assoc | Unclassified | $123.5M | $194.0M |
| 24 | Ex Students Association of the | Education | $123.1M | $220.5M |
| 25 | 2033 Fund | Education | $112.6M | $190.0M |
| 26 | Mulva Family Foundation | Philanthropy, Voluntarism & Grantmaking | $108.7M | $540.6M |
| 27 | Texas Access to Justice Foundation | Unclassified | $106.3M | $203.4M |
| 28 | Texas Association of School Boards INC | Education | $101.3M | $107.5M |
| 29 | Westminster Manor | Health Care | $100.9M | $307.7M |
| 30 | Education Service Center Region XIII | Education | $96.8M | $60.9M |
| 31 | Texas Property and Casualty Insurance Guaranty Association | Unclassified | $94.1M | $546.8M |
| 32 | Amplify Credit Union | Unclassified | $91.5M | $1.3B |
| 33 | National Campus and Community Development Corporation INC | Housing & Shelter | $90.4M | $1.2B |
| 34 | United Heritage Credit Union | Unclassified | $90.3M | $1.6B |
| 35 | Childrens Advocacy Centers of Texas INC | Crime & Legal-Related | $89.5M | $25.9M |
| 36 | Travis Association for the Blind | Diseases, Disorders & Medical Disciplines | $86.5M | $88.9M |
| 37 | Texas State Affordable Housing Corporation | Housing & Shelter | $85.6M | $491.0M |
| 38 | Rewild | Animal-Related | $75.0M | $84.0M |
| 39 | The University of Texas Texas a M Investment Management Company | Education | $74.6M | $80.4M |
| 40 | Texas Association of Realtors | Unclassified | $73.3M | $118.4M |
| 41 | We Are Blood | Health Care | $72.1M | $71.5M |
| 42 | Worksource Greater Austin Area Workforce Board | Employment | $71.1M | $20.3M |
| 43 | University of Texas Foundation | Unclassified | $69.5M | $98.0M |
| 44 | Alliance to End Plastic Waste INC | Environment | $68.3M | $169.8M |
| 45 | Concordia University Texas | Education | $66.5M | $163.0M |
| 46 | Texas Health Action | Health Care | $65.6M | $43.9M |
| 47 | Velocity Credit Union | Unclassified | $64.5M | $1.0B |
| 48 | Acton School of Business | Education | $61.7M | $96.8M |
| 49 | Hensel Phelps Construction Co Employee Benefit Tr | Mutual & Membership Benefit | $58.4M | $9.7M |
| 50 | Uatx | Education | $57.0M | $76.6M |
| 51 | Tmf Health Quality Institute | Health Care | $56.9M | $92.8M |
| 52 | Holdsworth Center | Philanthropy, Voluntarism & Grantmaking | $55.9M | $215.3M |
| 53 | Young Mens Christian Association | Human Services | $55.7M | $82.9M |
| 54 | Feeding Texas | Community Improvement & Capacity Building | $54.7M | $18.5M |
| 55 | Hector and Gloria Lopez Foundation | Philanthropy, Voluntarism & Grantmaking | $54.1M | $257.8M |
| 56 | Texas Pregnancy Care Network | Human Services | $53.7M | $11.3M |
| 57 | Mobile Loaves & Fishes INC | Religion-Related | $52.7M | $207.6M |
| 58 | Third Future Schools-texas | Education | $51.3M | $86.5M |
| 59 | Hospice Austin | Human Services | $50.8M | $18.4M |
| 60 | St. Andrews Episcopal School INC | Education | $50.6M | $131.1M |
| 61 | Foundation Communities INC | Housing & Shelter | $50.0M | $262.9M |
| 62 | Texas Association of County Officials | Unclassified | $48.9M | $92.3M |
| 63 | American Academy of Nurse Practitioners National | Health Care | $48.2M | $100.7M |
| 64 | Austin Affordable Housing Corporation | Housing & Shelter | $46.6M | $237.5M |
| 65 | Effie and Wofford Cain Foundation | Unclassified | $46.2M | $108.9M |
| 66 | University of Texas Law School Foundation | Education | $42.3M | $314.8M |
| 67 | Peoples Community Clinic INC | Health Care | $41.9M | $44.0M |
| 68 | Austin Achieve Public Schools INC | Education | $41.5M | $94.5M |
| 69 | Valor Texas Education Foundation | Education | $41.3M | $165.0M |
| 70 | Texas Casa INC | Civil Rights, Social Action & Advocacy | $39.5M | $18.5M |
| 71 | Foundation Communities | Housing & Shelter | $39.3M | $112.2M |
| 72 | Austin Habitat for Humanity INC | Unclassified | $38.9M | $75.8M |
| 73 | American Association of Nurses Practitioners INC | Unclassified | $37.1M | $49.7M |
| 74 | St. Vincent de Paul Rehabilitation Services of Texas INC | Employment | $36.5M | $24.2M |
| 75 | Goodwill Temporary Services INC | Employment | $35.7M | $4.0M |
| 76 | Austin Theatre Alliance | Arts, Culture & Humanities | $33.2M | $39.5M |
| 77 | The Safe Alliance | Unclassified | $32.6M | $12.3M |
| 78 | Harry E and Eda L Montandon Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $32.1M | $42.5M |
| 79 | Presbyterian Childrens Homes and Services | Human Services | $31.6M | $185.5M |
| 80 | The Onestar Foundation | Community Improvement & Capacity Building | $31.3M | $4.8M |
| 81 | Vivent Health Texas INC | Diseases, Disorders & Medical Disciplines | $31.2M | $59.2M |
| 82 | Emancipet | Animal-Related | $30.6M | $12.0M |
| 83 | The Physicians Foundation INC | Mental Health & Crisis Intervention | $30.5M | $128.0M |
| 84 | International Sustainable Energy Foundation | Environment | $30.1M | $48.2M |
| 85 | Ubongo International | Arts, Culture & Humanities | $29.2M | $32.3M |
| 86 | University Co-operative Society | Education | $29.1M | $23.0M |
| 87 | Texas Public Policy Foundation | Public & Societal Benefit | $29.1M | $27.6M |
| 88 | Huston-tillotson University | Unclassified | $28.6M | $63.9M |
| 89 | Texas One Fund INC | Community Improvement & Capacity Building | $28.2M | $604K |
| 90 | Bph Holding Co INC | Human Services | $28.2M | $189.2M |
| 91 | Peoplefund | Community Improvement & Capacity Building | $28.1M | $97.6M |
| 92 | Austin Convention and Visitors Bureau INC | Unclassified | $28.1M | $23.1M |
| 93 | Regents School of Austin INC | Education | $27.8M | $71.0M |
| 94 | National Domestic Violence Hotline | Human Services | $27.8M | $12.8M |
| 95 | Austin Country Club | Unclassified | $27.7M | $37.4M |
| 96 | Combined Law Enforcement Associations of Texas | Unclassified | $27.7M | $8.5M |
| 97 | Association of Texas Professional Educators | Unclassified | $26.9M | $26.5M |
| 98 | McCombs School of Business Foundation | Education | $26.5M | $50.5M |
| 99 | Lyndon Baines Johnson Foundation | Education | $26.4M | $284.1M |
| 100 | Texas Medical Association | Unclassified | $26.1M | $62.7M |