| 1 | Wayne Hospital Company | Health Care | $98.5M | $178.3M |
| 2 | Family Health Services of Darke County INC | Health Care | $50.3M | $43.1M |
| 3 | Brethren Retirement Community | Human Services | $29.1M | $47.9M |
| 4 | Darke Rural Electric Cooperative INC | Unclassified | $19.7M | $45.5M |
| 5 | Hospice of Darke County INC | Human Services | $10.9M | $12.0M |
| 6 | Light Foundation | Philanthropy, Voluntarism & Grantmaking | $9.1M | $7.7M |
| 7 | Darke County Recovery Services | Mental Health & Crisis Intervention | $6.0M | $2.5M |
| 8 | Darke County Foundation | Unclassified | $5.0M | $16.6M |
| 9 | Darke County Agricultural Society | Animal-Related | $2.9M | $9.6M |
| 10 | Cheeseman Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.5M | $465K |
| 11 | Darke County Young Mens Christian Association | Human Services | $2.1M | $2.7M |
| 12 | Good Samaritan Home INC | Crime & Legal-Related | $1.8M | $2.6M |
| 13 | 635 Members Choice Credit Union INC | Unclassified | $1.5M | $34.5M |
| 14 | Greenville Lodge No 329 Loyal Order of Moose | Unclassified | $1.5M | $2.2M |
| 15 | Decolores Montessori School | Education | $1.1M | $1.9M |
| 16 | Church of God Restoration- Ministerial Body INC | Religion-Related | $1.0M | $2.6M |
| 17 | Walled Garden | Human Services | $899K | $676K |
| 18 | Brethren Charity Fund INC | Education | $842K | $535K |
| 19 | Darke County Housing Corporation | Housing & Shelter | $716K | $1.1M |
| 20 | Darke County United Way INC | Philanthropy, Voluntarism & Grantmaking | $586K | $749K |
| 21 | Benevolent & Protective Order of Elks of the USA | Unclassified | $576K | $514K |
| 22 | Community Improvement Corporation of Darke County Ohio | Community Improvement & Capacity Building | $462K | $560K |
| 23 | Youth for Christ USA INC | Unclassified | $454K | $486K |
| 24 | Darke County Historical Society INC | Unclassified | $448K | $1.6M |
| 25 | Veterans of Foreign Wars of the United States Department of Ohio | Unclassified | $410K | $477K |
| 26 | Fraternal Order of Eagles | Unclassified | $400K | $1.8M |
| 27 | Wayne Hospital Foundation INC | Education | $335K | $867K |
| 28 | Darke County Sheriffs Patrol | Unclassified | $321K | $145K |
| 29 | Darke County Center for the Arts INC | Arts, Culture & Humanities | $315K | $136K |
| 30 | Green Wave Athletic Boosters | Education | $273K | $131K |
| 31 | Darke County Pregnancy Help Center INC | Human Services | $256K | $476K |
| 32 | International Union United Auto Aero Agri Impl Workers of America- | Unclassified | $247K | $45K |
| 33 | Cancer Association of Darke County | Diseases, Disorders & Medical Disciplines | $242K | $870K |
| 34 | Final Bow Center for Childrens Performing Arts | Youth Development | $220K | $18K |
| 35 | Matthew & Angela Arnold Foundation INC | Philanthropy, Voluntarism & Grantmaking | $216K | $336K |
| 36 | Darke County Visitors Bureau INC | Unclassified | $203K | $180K |
| 37 | Darke County Chamber of Commerce | Unclassified | $195K | $247K |
| 38 | Greenville Girls Softball Association INC | Recreation & Sports | $192K | $618K |
| 39 | Darke County Tractor Pullers Assoc INC | Recreation & Sports | $172K | $82K |
| 40 | Greenville Citizens Baseball League INC | Recreation & Sports | $140K | $229K |
| 41 | Yolo of Darke County INC | Community Improvement & Capacity Building | $135K | $137K |
| 42 | Brown Family Foundation INC | Unclassified | $131K | $701K |
| 43 | Shelter from Violence INC | Unclassified | $131K | $138K |
| 44 | Illumination Festival INC | Community Improvement & Capacity Building | $113K | $7K |
| 45 | Financial Assistance for Medical Emergencies INC | Unclassified | $109K | $461K |
| 46 | Gospel Training International INC | Education | $102K | $30K |
| 47 | Main Street Greenville INC | Community Improvement & Capacity Building | $96K | $91K |
| 48 | Grace Resurrection Association for Christian Endeavors INC | Human Services | $95K | $143K |
| 49 | Gospel Trumpet Publishing Co | Religion-Related | $87K | $499K |
| 50 | Boys & Girls Club of Greenville | Youth Development | $85K | $182K |
| 51 | Lydia Schaurer Memorial Trust Fund | Unclassified | $84K | $997K |
| 52 | Darke County Endowment for the Arts INC | Arts, Culture & Humanities | $84K | $547K |
| 53 | Ohio Wave Fastpitch Corporation | Recreation & Sports | $81K | $109K |
| 54 | Greenville Farm Power of the Past INC | Unclassified | $79K | $26K |
| 55 | Darke County Historical Society Endowment Fund INC | Arts, Culture & Humanities | $65K | $1.3M |
| 56 | Harry D Stephens Memorial INC | Unclassified | $64K | $6K |
| 57 | Darke County Soccer Association INC | Recreation & Sports | $59K | $23K |
| 58 | Rotary International | Unclassified | $57K | $30K |
| 59 | Greenville Ohio Schools Foundation INC | Education | $54K | $801K |
| 60 | Ansonia Parents Alliance | Education | $54K | $32K |
| 61 | Greenville Instrumental Boosters | Unclassified | $50K | $31K |
| 62 | Fish Choice Pantry | Food, Agriculture & Nutrition | $48K | $93K |
| 63 | Knights of Columbus | Unclassified | $47K | $109K |
| 64 | Darke County College Access Program | Education | $41K | $48K |
| 65 | Friends of Fort Jefferson | Arts, Culture & Humanities | $38K | $276K |
| 66 | Ketrow Foundation | Unclassified | $36K | $412K |
| 67 | Purfect Haven INC | Animal-Related | $36K | $1 |
| 68 | Community Improvement Corp of Greenville Ohio | Unclassified | $28K | $1.5M |
| 69 | Rotary Club of Greenville Ohio Foundation | Philanthropy, Voluntarism & Grantmaking | $25K | $148K |
| 70 | Darke Rural Electric Trust INC | Philanthropy, Voluntarism & Grantmaking | $23K | $120 |
| 71 | Darke Elks Benevolence Group | Mental Health & Crisis Intervention | $11K | $0 |
| 72 | Community Christmas Dinner of Darke County Ohio | Public & Societal Benefit | $9K | $7K |
| 73 | Fhs Support Corporation | Health Care | $8K | $24.7M |
| 74 | Sam Barga Memorial Foundation | Education | $611 | $6K |
| 75 | Dustin Brodrick Foundation INC | Human Services | $100 | $200 |
| 76 | The Greenville Municipal Concert Band INC | Arts, Culture & Humanities | $0 | $0 |
| 77 | The Ohio State University | Youth Development | $0 | $0 |
| 78 | Darke County Weekday Christian Education INC | Religion-Related | $0 | $0 |
| 79 | Rocketship Sports | Recreation & Sports | $0 | $0 |
| 80 | Annie Oakley Committee Incorporated | Unclassified | $0 | $0 |
| 81 | Miami Valley Moose Legion No 103 | Unclassified | $0 | $0 |
| 82 | Greenville Chapter No 102 Women of the Moose | Unclassified | $0 | $0 |
| 83 | Order of the Eastern Star of Ohio | Unclassified | $0 | $0 |
| 84 | Northside Community Fellowship | Religion-Related | $0 | $0 |
| 85 | Darke County Area Emmaus Communityinc | Religion-Related | $0 | $0 |
| 86 | PTA Ohio Congress | Unclassified | $0 | $0 |
| 87 | PTA Ohi Congress | Unclassified | $0 | $0 |
| 88 | Greenville Art Guild | Arts, Culture & Humanities | $0 | $0 |
| 89 | The Ohio State University | Youth Development | $0 | $0 |
| 90 | Annie Oakley Center Foundation INC | Arts, Culture & Humanities | $0 | $0 |
| 91 | The Ohio State University | Youth Development | $0 | $0 |
| 92 | Darke County Harness Horsemen | Animal-Related | $0 | $0 |
| 93 | The Ohio State University | Youth Development | $0 | $0 |
| 94 | Greenville Area Dog Club INC | Unclassified | $0 | $0 |
| 95 | The Ohio State University | Youth Development | $0 | $0 |
| 96 | Darke County Senior Outreach INC | Human Services | $0 | $0 |
| 97 | The Ohio State University | Youth Development | $0 | $0 |
| 98 | The Ohio State University | Youth Development | $0 | $0 |
| 99 | The Ohio State University | Youth Development | $0 | $0 |
| 100 | The Ohio State University | Youth Development | $0 | $0 |