| 1 | Caresource Ohio INC | Health Care | $15.4B | $2.2B |
| 2 | Caresource Indiana INC | Health Care | $2.7B | $437.4M |
| 3 | Caresource Georgia Co | Health Care | $2.3B | $657.1M |
| 4 | Miami Valley Hospital | Health Care | $1.9B | $1.5B |
| 5 | Caresource | Health Care | $1.5B | $2.8B |
| 6 | University of Dayton | Education | $1.0B | $2.2B |
| 7 | Dayton Childrens Hospital | Health Care | $836.6M | $1.8B |
| 8 | Caresource West Virginia Co | Health Care | $802.0M | $139.6M |
| 9 | Caresource Kentucky Co | Health Care | $390.0M | $56.3M |
| 10 | Atrium Medical Center | Health Care | $348.3M | $275.1M |
| 11 | Heartland Health & Wellness Fund | Health Care | $347.8M | $40.9M |
| 12 | Community Blood Center | Health Care | $344.1M | $541.6M |
| 13 | Upper Valley Medical Center | Health Care | $242.3M | $405.5M |
| 14 | Charles F Kettering Foundation | Unclassified | $179.3M | $469.1M |
| 15 | Uvmc | Unclassified | $113.0M | $0 |
| 16 | Goodwill Easter Seals Miami Valley | Employment | $111.0M | $108.9M |
| 17 | The Hospice of Dayton INC | Human Services | $98.4M | $79.8M |
| 18 | Area Agency on Aging Planning and Service Area 2 | Human Services | $74.9M | $45.6M |
| 19 | Graceworks Lutheran Services | Human Services | $69.7M | $151.3M |
| 20 | 1307 Day Air Credit Union INC | Unclassified | $67.8M | $816.2M |
| 21 | Dayton Foundation | Philanthropy, Voluntarism & Grantmaking | $65.7M | $649.6M |
| 22 | Uvmc Nursing Care INC | Health Care | $59.9M | $5.0M |
| 23 | Miami Valley Child Development Centers INC | Human Services | $53.3M | $26.2M |
| 24 | Five Rivers Health Centers | Health Care | $50.7M | $52.7M |
| 25 | Miami Valley Hospital Foundation | Health Care | $46.6M | $82.3M |
| 26 | Dayton Childrens Hospital Foundation | Health Care | $43.6M | $183.9M |
| 27 | Graceworks Lutheran Services | Human Services | $43.0M | $26.7M |
| 28 | Young Mens Christian Association of Greater Dayton | Unclassified | $40.6M | $73.7M |
| 29 | Foodbank INC | Food, Agriculture & Nutrition | $36.0M | $27.9M |
| 30 | Catholic Social Servies of the Miami Valley | Unclassified | $32.8M | $16.0M |
| 31 | Mathile Family Foundation | Philanthropy, Voluntarism & Grantmaking | $30.9M | $291.9M |
| 32 | Cpps Heritage Mission Fund | Religion-Related | $30.6M | $26.3M |
| 33 | Eastway Corporation | Mental Health & Crisis Intervention | $29.4M | $19.9M |
| 34 | Wright Brothers Institute INC | Community Improvement & Capacity Building | $29.0M | $5.5M |
| 35 | Dayton Foundation Depository | Philanthropy, Voluntarism & Grantmaking | $28.1M | $43.0M |
| 36 | 0197 Universal 1 Credit Union INC | Unclassified | $26.4M | $417.7M |
| 37 | Ohios Hospice INC | Health Care | $26.1M | $27.4M |
| 38 | United Food and Commercial Workers International Union | Unclassified | $25.6M | $18.8M |
| 39 | Victoria Theatre Association | Arts, Culture & Humanities | $24.4M | $36.9M |
| 40 | Childrens Home Care of Dayton | Health Care | $23.4M | $34.0M |
| 41 | Wright State University Foundation INC | Education | $20.5M | $172.6M |
| 42 | Miami Valley Community Action Partnership | Human Services | $20.3M | $17.6M |
| 43 | Kettering Family Foundation | Unclassified | $20.3M | $90.6M |
| 44 | South Community INC | Health Care | $19.0M | $6.8M |
| 45 | Deca Prep INC | Education | $19.0M | $20.1M |
| 46 | Dayton Art Institute | Arts, Culture & Humanities | $18.7M | $31.7M |
| 47 | Dayton Foundation Plus INC | Philanthropy, Voluntarism & Grantmaking | $18.7M | $441.9M |
| 48 | Atrium Medical Center Foundation | Health Care | $18.2M | $32.6M |
| 49 | Uvpc Specialists INC | Health Care | $18.0M | $3.9M |
| 50 | Homefull | Human Services | $17.9M | $16.1M |
| 51 | Choices in Community Living INC | Human Services | $17.4M | $8.8M |
| 52 | Calvary Cemetery Association of Dayton Ohio | Unclassified | $17.2M | $44.6M |
| 53 | Air Force Museum Foundation INC | Arts, Culture & Humanities | $16.6M | $32.9M |
| 54 | Dayton Power & Light Company Foundation | Unclassified | $13.7M | $26.0M |
| 55 | Greater Dayton Area Hospital Assoc | Unclassified | $12.9M | $6.3M |
| 56 | Samaritan Behavioral Health INC | Health Care | $12.8M | $3.3M |
| 57 | Preschool Promise INC | Education | $12.1M | $5.3M |
| 58 | Community Health Centers of Greater Dayton | Health Care | $11.9M | $4.4M |
| 59 | County Corp. | Housing & Shelter | $11.7M | $22.1M |
| 60 | Educational Resources INC | Unclassified | $11.7M | $22.2M |
| 61 | Klepinger Community School | Education | $11.6M | $17.1M |
| 62 | Levin Family Foundation | Unclassified | $11.3M | $20.9M |
| 63 | St. Vincent de Paul Social Services INC | Human Services | $10.4M | $13.1M |
| 64 | Alliance Community Schools INC | Education | $10.2M | $3.4M |
| 65 | 1368 Code Credit Union | Unclassified | $9.8M | $163.4M |
| 66 | Ohios Hospice Foundation | Health Care | $9.5M | $41.5M |
| 67 | Premier Health Partners | Religion-Related | $9.4M | $80.8M |
| 68 | Dayton Society of Natural History Dayton Museum of Natural History | Arts, Culture & Humanities | $9.3M | $23.2M |
| 69 | Omega Community Development Corporation | Human Services | $9.2M | $11.5M |
| 70 | Graceworks Lutheran Services Health Benefit Trust | Unclassified | $9.2M | $2.0M |
| 71 | Dayton Early College Academy INC | Education | $9.2M | $18.8M |
| 72 | Miami Valley Housing Opportunities INC | Housing & Shelter | $9.1M | $17.8M |
| 73 | Nova Behavioral Health INC | Mental Health & Crisis Intervention | $9.0M | $8.0M |
| 74 | American Legion | Unclassified | $9.0M | $214K |
| 75 | Good Samaritan Foundation-dayton | Unclassified | $8.9M | $13.7M |
| 76 | Woodland Cemetery Assoc of Dayton | Unclassified | $8.8M | $46.9M |
| 77 | Richard Allen Preparatory INC | Education | $8.8M | $6.0M |
| 78 | Moraine Country Club | Unclassified | $8.8M | $15.0M |
| 79 | Sinclair Community College Foundation | Education | $8.8M | $46.3M |
| 80 | Resident Home Association of Greater Dayton INC | Human Services | $8.5M | $6.1M |
| 81 | Jesse and Caryl Philips Foundation | Unclassified | $8.4M | $18.5M |
| 82 | Dayton Performing Arts Alliance | Arts, Culture & Humanities | $8.2M | $12.9M |
| 83 | Ohio Baseball Club | Recreation & Sports | $7.9M | $273K |
| 84 | St. Vincent Depaul Society District Council of Dayton Ohio INC | Human Services | $7.9M | $21.3M |
| 85 | Senior Resource Connection | Human Services | $7.8M | $2.5M |
| 86 | Dayton-miami Valley Entrepreneurs Center | Community Improvement & Capacity Building | $7.7M | $4.3M |
| 87 | Dayton Development Coalition INC | Unclassified | $7.7M | $5.8M |
| 88 | Treadwell Credit Union | Unclassified | $7.7M | $122.7M |
| 89 | Daybreak INC | Human Services | $7.5M | $12.9M |
| 90 | International Association of Sheet Metal Air Rail & Transportation | Employment | $7.4M | $13.8M |
| 91 | Dayton History | Arts, Culture & Humanities | $7.4M | $68.1M |
| 92 | Ronald McDonald House Charities Dayton | Unclassified | $7.1M | $44.4M |
| 93 | United Rehabilitation Services of Greater Dayton | Unclassified | $7.1M | $13.0M |
| 94 | St. Mary Development Corporation | Housing & Shelter | $6.8M | $40.8M |
| 95 | Habitat for Humanity International INC | Unclassified | $6.7M | $8.1M |
| 96 | Humane Society of Greater Dayton | Animal-Related | $6.6M | $15.4M |
| 97 | Crayons to Classrooms | Education | $6.4M | $4.6M |
| 98 | Lions Eye Bank of West Central Ohio | Unclassified | $6.2M | $7.4M |
| 99 | Miami Valley Warhawks Baseball Club | Unclassified | $6.1M | $82K |
| 100 | Dayton Country Club Company | Unclassified | $6.1M | $7.4M |