| 1 | Mercyfirst | Human Services | $56.4M | $28.1M |
| 2 | Variety Child Learning Center | Education | $25.2M | $9.9M |
| 3 | Les Paul Foundation | Philanthropy, Voluntarism & Grantmaking | $11.6M | $42.3M |
| 4 | Allen E and Patricia M Murray Foundation | Philanthropy, Voluntarism & Grantmaking | $6.2M | $13.6M |
| 5 | Long Island School for the Gifted | Education | $4.0M | $3.8M |
| 6 | Arun and Neelam Gupta Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.5M | $6.7M |
| 7 | Christian Fellowship House | Human Services | $3.2M | $2.0M |
| 8 | New York College of Health Professions | Unclassified | $2.8M | $16.4M |
| 9 | Gsd Advisers INC | Education | $2.3M | $261K |
| 10 | Knott Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.1M | $5.1M |
| 11 | The Berg Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.0M | $5.5M |
| 12 | Natalie Bailey & Herbert J Kirshner Foundation | Philanthropy, Voluntarism & Grantmaking | $1.5M | $2.6M |
| 13 | Chin Ying Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $12.9M |
| 14 | American Mime INC | Unclassified | $1.2M | $4.7M |
| 15 | Syosset Volunteer and Exempt Firemens Benevolent Association | Unclassified | $1.1M | $2.8M |
| 16 | Edward and Susan Blumenfeld Foundation | Philanthropy, Voluntarism & Grantmaking | $919K | $2.7M |
| 17 | Childrens Medical Fund of New York | Health Care | $914K | $894K |
| 18 | Syosset Soccer Club INC | Unclassified | $850K | $368K |
| 19 | American Federation of Teachers | Unclassified | $774K | $322K |
| 20 | Erase Racism INC | Civil Rights, Social Action & Advocacy | $742K | $229K |
| 21 | Still Got Game Foundation INC | Youth Development | $634K | $1.1M |
| 22 | Childrens Medical Fund Child Life Endowment Corp. | Health Care | $505K | $784K |
| 23 | Syosset Baseball Association INC | Recreation & Sports | $392K | $370K |
| 24 | Commercial Industrial Brokers Society | Community Improvement & Capacity Building | $361K | $145K |
| 25 | Alpha Omega International Dental Fraternity INC | Unclassified | $333K | $176K |
| 26 | Arj Charitable Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $267K | $1.3M |
| 27 | Top Shelf Amateur Hockey Association INC | Recreation & Sports | $261K | $11K |
| 28 | Syosset Teachers Association Trust Fund | Unclassified | $255K | $1.0M |
| 29 | Zelniker Scherr Foundation | Philanthropy, Voluntarism & Grantmaking | $239K | $577K |
| 30 | Syosset Fire Department INC | Public Safety, Disaster Preparedness & Relief | $238K | $515K |
| 31 | West Side School Parent Teacher Group INC | Education | $238K | $101K |
| 32 | Emmaus House Foundation INC | Housing & Shelter | $208K | $2.6M |
| 33 | Syosset Fire Company No 1 INC | Public Safety, Disaster Preparedness & Relief | $199K | $195K |
| 34 | Brad and Francie Blumenfeld Family Foundation | Philanthropy, Voluntarism & Grantmaking | $188K | $769K |
| 35 | Nassau County Police Reserve Association Scholarship Fund INC | Unclassified | $180K | $462K |
| 36 | American Federation of Teachers | Unclassified | $177K | $76K |
| 37 | No Peace Without Justice International Committee | International, Foreign Affairs & National Security | $160K | $11K |
| 38 | Stages on the Sound INC | Arts, Culture & Humanities | $149K | $55K |
| 39 | Asian American Institute for Research & Engagement | Social Science | $130K | $100K |
| 40 | Civil Service Employees Association | Unclassified | $130K | $49K |
| 41 | Dante Foundation of Nassau County INC | Philanthropy, Voluntarism & Grantmaking | $124K | $217K |
| 42 | PTA New York Congress | Unclassified | $120K | $38K |
| 43 | Dr Edward B Shils Entrepreneurial Fund INC | Public & Societal Benefit | $110K | $379K |
| 44 | Long Island Curling Club | Human Services | $103K | $218K |
| 45 | Timothy Ogrady Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $95K | $13K |
| 46 | Mpmaana INC | Health Care | $94K | $71K |
| 47 | Syosset Woodbury Chamber of Commerce INC | Community Improvement & Capacity Building | $94K | $107K |
| 48 | Shri Padmavati Shakti Peeth INC | Religion-Related | $75K | $131K |
| 49 | Alliance for Oral Health Across Borders INC | International, Foreign Affairs & National Security | $70K | $22K |
| 50 | Schack Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $64K | $477K |
| 51 | Long Island Language Arts Council INC | Education | $64K | $142K |
| 52 | Evangelical Mission Society of America INC | International, Foreign Affairs & National Security | $59K | $14K |
| 53 | PTA New York Congress | Unclassified | $52K | $51K |
| 54 | Sabrina Navaretta Memorial Foundation INC | Human Services | $49K | $131K |
| 55 | Wann Family Foundation | Philanthropy, Voluntarism & Grantmaking | $45K | $760K |
| 56 | Syosset Youth Lacrosse Sylax INC | Recreation & Sports | $34K | $67K |
| 57 | Lawrence and Marilyn Kaplan Foundation | Philanthropy, Voluntarism & Grantmaking | $30K | $293K |
| 58 | American Accordionist Association INC | Education | $24K | $79K |
| 59 | Fuel for Truth INC | Religion-Related | $22K | $148K |
| 60 | Polyglot Ua | Education | $17K | $54K |
| 61 | Covenant INC | Philanthropy, Voluntarism & Grantmaking | $17K | $4K |
| 62 | Love from Lauren Foundation INC | Philanthropy, Voluntarism & Grantmaking | $14K | $116K |
| 63 | Virtue Project INC | Animal-Related | $11K | $2K |
| 64 | Syosset Lacrosse Booster Club INC | Education | $11K | $22K |
| 65 | Gupta Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $10K | $1 |
| 66 | Anuj Agarwa Memorial Fund | International, Foreign Affairs & National Security | $3K | $103K |
| 67 | Gilgal Divine Reief Center Incl | International, Foreign Affairs & National Security | $3K | $8K |
| 68 | Long Island Youth for Future INC | Youth Development | $3K | $8K |
| 69 | Sottovoce Foundation | Philanthropy, Voluntarism & Grantmaking | $2K | $79K |
| 70 | Transformation Through INC | Philanthropy, Voluntarism & Grantmaking | $1K | $32K |
| 71 | New York Crohns and Colitis Organization | Diseases, Disorders & Medical Disciplines | $1K | $77K |
| 72 | Smile in a Bag INC | Human Services | $180 | $7K |
| 73 | Medhat F Sami Foundation INC | Unclassified | $1 | $3.3M |
| 74 | Eugene and Monica E Hollander Foundation | Unclassified | $1 | $12K |
| 75 | Daniel Gold Memorial Foundation INC | Mental Health & Crisis Intervention | $1 | $36K |
| 76 | Miahs Hope INC | Diseases, Disorders & Medical Disciplines | $1 | $1 |
| 77 | Unity Heart Foundation | Human Services | $1 | $1 |
| 78 | Glad Tidings Christian Fellowship Corp. | Religion-Related | $0 | $0 |
| 79 | Mary Stolfa Cancer Foundation | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 80 | Sons of Italy in America | Mutual & Membership Benefit | $0 | $0 |
| 81 | Korean Baptist Church of Ny | Unclassified | $0 | $0 |
| 82 | St. Bedes Church | Unclassified | $0 | $0 |
| 83 | Town of Oyster Bay Arts Council INC | Unclassified | $0 | $0 |
| 84 | Orthodox Church in America | Unclassified | $0 | $0 |
| 85 | Annandale Drive Homeowners Assn. | Unclassified | $0 | $0 |
| 86 | Civil Service Employees Association | Unclassified | $0 | $0 |
| 87 | PTA New York Congress | Unclassified | $0 | $0 |
| 88 | PTA New York Congress | Unclassified | $0 | $0 |
| 89 | New York Mustard Seed Church | Unclassified | $0 | $0 |
| 90 | PTA New York Congress | Unclassified | $0 | $0 |
| 91 | PTA New York Congress | Unclassified | $0 | $0 |
| 92 | Catholic Daughters of the Americas | Unclassified | $0 | $0 |
| 93 | PTA New York Congress | Unclassified | $0 | $0 |
| 94 | Association of Contractors and Fabricators of N Y C INC | Unclassified | $0 | $0 |
| 95 | Metropolitan Woodworkers Assoc of New York INC | Unclassified | $0 | $0 |
| 96 | The Holy Spirit Church of New York | Religion-Related | $0 | $0 |
| 97 | Northeast American Diocese of the Malankara Orthodox Syrian Church | Unclassified | $0 | $0 |
| 98 | Saint Baselios Malankara Orthodox Syrian Church | Religion-Related | $0 | $0 |
| 99 | Russian Mission Church | Religion-Related | $0 | $0 |
| 100 | Rainbow Mission USA INC | Religion-Related | $0 | $0 |