| 1 | UPMC Chautauqua at Wca | Health Care | $181.9M | $120.4M |
| 2 | Nysarc INC | Human Services | $100.1M | $52.5M |
| 3 | Chautauqua Region Community Foundation INC | Philanthropy, Voluntarism & Grantmaking | $41.8M | $148.0M |
| 4 | National Comedy Center Operator INC | Arts, Culture & Humanities | $25.9M | $20.2M |
| 5 | Gebbie Foundation INC | Unclassified | $10.9M | $79.2M |
| 6 | Southern Tier Building Trades Welfare Plan | Unclassified | $8.7M | $20.5M |
| 7 | Jamestown Community College Foundation INC | Education | $8.0M | $29.8M |
| 8 | William B Anderson and Juliet J Anderson Rosch Charitable | Philanthropy, Voluntarism & Grantmaking | $5.4M | $6.9M |
| 9 | I B E W Health and Welfare Benefit Trust Fund - Local Union 106 | Unclassified | $4.9M | $7.8M |
| 10 | Young Mens Christian Assoc Jamestown | Human Services | $4.7M | $5.5M |
| 11 | James Prendergast Library Association | Education | $4.3M | $10.9M |
| 12 | Jamestown Center City Development Corporation | Community Improvement & Capacity Building | $4.2M | $25.1M |
| 13 | Wca Foundation INC | Philanthropy, Voluntarism & Grantmaking | $4.2M | $20.4M |
| 14 | Hultquist Foundation INC | Unclassified | $4.0M | $15.1M |
| 15 | National Comedy Center INC | Arts, Culture & Humanities | $3.8M | $4.8M |
| 16 | W I B INC | Employment | $3.6M | $1.0M |
| 17 | Lutheran Social Services Foundation of Upstate New York INC | Philanthropy, Voluntarism & Grantmaking | $3.6M | $20.4M |
| 18 | Moon Brook Country Club INC | Unclassified | $3.1M | $2.4M |
| 19 | Ralph C Sheldon Foundation INC | Unclassified | $2.7M | $11.2M |
| 20 | Jamestown Campus of the Jamestown Comm Col Faculty Student Assoc INC | Unclassified | $2.4M | $1.8M |
| 21 | International Association of Machinists & Aerospace Workers | Employment | $2.4M | $762K |
| 22 | Young Womens Christian Assn. | Human Services | $2.3M | $1.7M |
| 23 | United Way of Southern Chautauqua County | Philanthropy, Voluntarism & Grantmaking | $2.1M | $3.6M |
| 24 | Jamestown Community Learning Council | Education | $2.1M | $2.9M |
| 25 | Prevention Works INC | Mental Health & Crisis Intervention | $1.8M | $345K |
| 26 | Chautauqua-cattaraugus Library System | Education | $1.7M | $1.5M |
| 27 | Rtpi of Natural History | Unclassified | $1.6M | $3.2M |
| 28 | Chautauqua Region Industrial Development Corporation | Community Improvement & Capacity Building | $1.6M | $1.9M |
| 29 | Reg Lenna Center for the Arts INC | Unclassified | $1.5M | $7.5M |
| 30 | Lutheran Social Services Group INC | Unclassified | $1.4M | $2.4M |
| 31 | Chautauqua Adult Day Care Centers Incorporated | Human Services | $1.4M | $2.2M |
| 32 | Chautauqua Striders INC | Youth Development | $1.3M | $2.1M |
| 33 | Winifred Crawford Dibert Boys and Girls Club of Jamestown INC | Unclassified | $1.2M | $2.8M |
| 34 | Community Inclusion INC | Housing & Shelter | $1.2M | $1.1M |
| 35 | Lake View Cemetery Association | Unclassified | $1.2M | $6.1M |
| 36 | Chautauqua Lake and Watershed Management Alliance INC | Environment | $1.1M | $1.0M |
| 37 | Chautauqua Christian Academy | Education | $1.0M | $402K |
| 38 | Friends of the Chautauqua County Child Advocacy Program INC | Crime & Legal-Related | $1.0M | $764K |
| 39 | Chautauqua Resources INC | Unclassified | $972K | $7.0M |
| 40 | Audubon Community Nature Center | Environment | $968K | $3.4M |
| 41 | St. Susan Center INC | Unclassified | $943K | $1.0M |
| 42 | Filling the Gap INC | Community Improvement & Capacity Building | $928K | $1.3M |
| 43 | Mental Health Association in New York State INC | Mental Health & Crisis Intervention | $927K | $102K |
| 44 | Family Service of the Chautauqua Region INC | Human Services | $925K | $514K |
| 45 | Waterfront Foundation INC | Health Care | $917K | $8.6M |
| 46 | International Brotherhood of Electrical Workers | Unclassified | $819K | $4.1M |
| 47 | Holmberg Foundation INC | Unclassified | $789K | $4.8M |
| 48 | Kiantone Independent Fire Dept INC | Public Safety, Disaster Preparedness & Relief | $780K | $1.6M |
| 49 | Infinity Visual and Performing Arts INC | Unclassified | $778K | $1.7M |
| 50 | Citizens Opportunity for Development & Equality INC | Community Improvement & Capacity Building | $750K | $2.0M |
| 51 | Southwestern Independent Living Center INC | Human Services | $743K | $861K |
| 52 | United Christian Advocacy Network | Crime & Legal-Related | $740K | $849K |
| 53 | Chautauqua County Health Network INC | Health Care | $666K | $1.9M |
| 54 | Carnahan-jackson Foundation | Unclassified | $647K | $9.3M |
| 55 | Robert H Jackson Center INC | Arts, Culture & Humanities | $638K | $4.3M |
| 56 | Chautauqua County Chamber of Commerce | Community Improvement & Capacity Building | $575K | $822K |
| 57 | New Vision Services INC | Human Services | $569K | $508K |
| 58 | Meals on Wheels Jamestown Area INC | Food, Agriculture & Nutrition | $545K | $229K |
| 59 | Chautauqua Community Residence INC | Housing & Shelter | $486K | $862K |
| 60 | Team Services INC | Human Services | $486K | $396K |
| 61 | Benevolent & Protective Order of Elks of the USA | Unclassified | $467K | $147K |
| 62 | Roger Tory Peterson Institute of Natural History Foundation | Arts, Culture & Humanities | $445K | $1.7M |
| 63 | New Life Radio International Nfp | Religion-Related | $437K | $581K |
| 64 | Chautauqua-cattaraugus Board of Realtors INC | Unclassified | $433K | $374K |
| 65 | Mu Chapter of Sigma Pi Educational Foundation INC | Education | $418K | $97K |
| 66 | Fraternal Order of Eagles | Unclassified | $371K | $409K |
| 67 | American Federation of Teachers | Unclassified | $356K | $135K |
| 68 | Jamestown Renaissance Corporation | Community Improvement & Capacity Building | $352K | $1.1M |
| 69 | Chautauqua Blind Association INC | Diseases, Disorders & Medical Disciplines | $350K | $874K |
| 70 | Busti Fire Dept INC | Unclassified | $350K | $3.2M |
| 71 | American Legion | Public & Societal Benefit | $320K | $517K |
| 72 | Chautauqua Connections INC | Community Improvement & Capacity Building | $319K | $1.2M |
| 73 | Fenton Historical Society | Unclassified | $301K | $360K |
| 74 | International Union United Auto Aerospace & Agriculture Workers | Unclassified | $296K | $83K |
| 75 | Jamestown Vietnam Veterans Association INC | Recreation & Sports | $255K | $395K |
| 76 | Chautauqua Regional Youth Ballet INC | Arts, Culture & Humanities | $243K | $99K |
| 77 | Collaborative Childrens Solutions INC | Community Improvement & Capacity Building | $232K | $22K |
| 78 | Dream It Do It Western New York INC | Education | $232K | $198K |
| 79 | Joint Apprenticeship & Training Committee | Unclassified | $229K | $547K |
| 80 | Creche INC | Human Services | $217K | $446K |
| 81 | Fourth Street Housing Development Fund Company INC | Housing & Shelter | $214K | $1.8M |
| 82 | Chautauqua County Youth Hockey Association | Unclassified | $198K | $104K |
| 83 | Italian-american Charity Golf Assoc INC | Philanthropy, Voluntarism & Grantmaking | $197K | $123K |
| 84 | Phi Delta Theta Educational Foundation of Meadville Pa | Unclassified | $192K | $424K |
| 85 | Little Theatre of Jamestown INC | Arts, Culture & Humanities | $187K | $674K |
| 86 | Choose Life of Jamestown INC | Unclassified | $157K | $179K |
| 87 | Rotary Club of Jamestown Community Service Fund INC | Human Services | $155K | $123K |
| 88 | Love INC of Southern Chautauqua County | Human Services | $144K | $34K |
| 89 | Chautauqua Sports Hall of Fame INC | Recreation & Sports | $134K | $372K |
| 90 | Chautauqua County Community Cultural Educational and Philanthr | Community Improvement & Capacity Building | $122K | $70K |
| 91 | Impact Campus Fellowship INC | Youth Development | $111K | $78K |
| 92 | Manufacturers Association of the Southern Tier INC | Unclassified | $106K | $575K |
| 93 | Hazeltine Public Library | Unclassified | $103K | $132K |
| 94 | Jamestown Band and Chorus Association INC | Arts, Culture & Humanities | $95K | $68K |
| 95 | Jamestown Area Midget Football INC | Recreation & Sports | $95K | $15K |
| 96 | Elizabeth Warner Marvin Community House INC | Human Services | $81K | $619K |
| 97 | The Kendall Club Police Benevolent Association INC | Unclassified | $78K | $699K |
| 98 | Fund for the Arts of Chautauqua County INC | Arts, Culture & Humanities | $75K | $3K |
| 99 | American Scandinavian Heritage Foundation INC | Unclassified | $74K | $37K |
| 100 | 96TH Highlanders Pipes & Drum INC | Arts, Culture & Humanities | $72K | $71K |