| 1 | The Hagan Scholarship Foundation | Education | $540.9M | $293.5M |
| 2 | Columbia College | Education | $460.5M | $241.0M |
| 3 | Ch Allied Services INC | Health Care | $438.8M | $238.0M |
| 4 | Midway USA Foundation INC | Philanthropy, Voluntarism & Grantmaking | $89.7M | $359.7M |
| 5 | Boone Electric Cooperative | Unclassified | $76.4M | $224.1M |
| 6 | Hagan Trust | Philanthropy, Voluntarism & Grantmaking | $43.8M | $268.6M |
| 7 | Oats INC | Human Services | $41.6M | $49.0M |
| 8 | Missouri United Methodist | Unclassified | $38.8M | $123.7M |
| 9 | Stephens College | Education | $33.6M | $94.0M |
| 10 | Veterans United Foundation | Philanthropy, Voluntarism & Grantmaking | $28.5M | $38.7M |
| 11 | The Food Bank for Central & Northeast Missouri INC | Food, Agriculture & Nutrition | $27.3M | $24.9M |
| 12 | Masonic Home of Missouri | Human Services | $27.0M | $196.5M |
| 13 | Central Missouri Community Action | Unclassified | $25.6M | $14.8M |
| 14 | Woodhaven Learning Center | Unclassified | $23.6M | $26.0M |
| 15 | Alternative Community Training INC | Employment | $17.6M | $18.0M |
| 16 | Central Missouri Area Agency on Aging | Human Services | $15.7M | $6.8M |
| 17 | Grand Lodge Af & Am of Mo | Unclassified | $13.7M | $32.2M |
| 18 | Deaflead | Education | $13.6M | $4.6M |
| 19 | Boone County Senior Citizen Service Corporation | Human Services | $13.3M | $7.6M |
| 20 | Missouri School Boards Association | Unclassified | $12.4M | $7.4M |
| 21 | Missouri State High School Activities Association | Unclassified | $11.6M | $9.1M |
| 22 | Missouri Association of Realtors | Unclassified | $11.3M | $20.8M |
| 23 | Mobius | Education | $10.9M | $3.9M |
| 24 | Religion News Foundation | Religion-Related | $9.5M | $9.2M |
| 25 | Columbia Independent School INC | Education | $8.7M | $24.7M |
| 26 | Central Missouri Humane Society | Animal-Related | $8.2M | $6.9M |
| 27 | Boone Hospital Foundation | Health Care | $7.9M | $20.6M |
| 28 | The Country Club of Missouri | Unclassified | $7.4M | $10.7M |
| 29 | Missouri State Teachers Association | Unclassified | $7.0M | $6.9M |
| 30 | Love Columbia Corp. | Human Services | $6.5M | $8.1M |
| 31 | University of Missouri Law School Foundation | Unclassified | $6.0M | $75.7M |
| 32 | Life Christian Outreach INC | Arts, Culture & Humanities | $5.7M | $3.4M |
| 33 | Kroenke Family Foundation | Philanthropy, Voluntarism & Grantmaking | $5.1M | $32.0M |
| 34 | Orthopedic Foundation for Animals | Unclassified | $5.1M | $13.9M |
| 35 | General Baptist Nursing Home INC | Unclassified | $5.0M | $5.2M |
| 36 | Voluntary Action Center | Philanthropy, Voluntarism & Grantmaking | $4.9M | $7.2M |
| 37 | M F a Foundation | Philanthropy, Voluntarism & Grantmaking | $4.8M | $19.5M |
| 38 | Investigative Reporters and Editors INC | Arts, Culture & Humanities | $4.8M | $8.9M |
| 39 | Margaret L Miller Trust | Unclassified | $4.5M | $11.5M |
| 40 | Community Foundation of Central Missouri | Philanthropy, Voluntarism & Grantmaking | $4.4M | $15.7M |
| 41 | State Historical Society of Missouri | Unclassified | $4.4M | $10.9M |
| 42 | Independent Living Center of Mid- Missouri INC | Health Care | $4.0M | $4.7M |
| 43 | Columbia Foundation | Philanthropy, Voluntarism & Grantmaking | $4.0M | $5.4M |
| 44 | Ronald McDonald House Charities of Mid-mo INC | Health Care | $3.8M | $14.7M |
| 45 | Missouri 4-H Foundation | Unclassified | $3.7M | $12.1M |
| 46 | St. Raymonds Society | Human Services | $3.7M | $11.2M |
| 47 | Welcome Home INC | Unclassified | $3.6M | $4.8M |
| 48 | University of Missouri Alumni Assn. | Education | $3.6M | $19.5M |
| 49 | Habitat for Humanity International INC | Housing & Shelter | $3.4M | $8.5M |
| 50 | David B Lichtenstein Foundation | Unclassified | $3.2M | $11.6M |
| 51 | Missouri Prairie Foundation | Environment | $3.2M | $19.5M |
| 52 | Job Point | Human Services | $3.2M | $2.2M |
| 53 | Heart of Missouri United Way INC | Unclassified | $3.1M | $3.9M |
| 54 | Central Missouri Subcontracting Enterprises | Employment | $2.9M | $2.9M |
| 55 | Thompson Foundation for Autism & Neurodevelopment | Diseases, Disorders & Medical Disciplines | $2.9M | $443K |
| 56 | Shelter Insurance Foundation | Education | $2.9M | $16.7M |
| 57 | In2action | Unclassified | $2.8M | $2.9M |
| 58 | City of Refuge | Human Services | $2.7M | $4.1M |
| 59 | Heart of Missouri Casa | Crime & Legal-Related | $2.7M | $2.3M |
| 60 | Assistance League of Mid-missouri | Unclassified | $2.6M | $2.3M |
| 61 | Laurie Foundation for the Performing Arts | Arts, Culture & Humanities | $2.6M | $5.8M |
| 62 | Boy Scouts of America | Youth Development | $2.6M | $10.6M |
| 63 | True North of Columbia INC | Human Services | $2.5M | $4.3M |
| 64 | Missouri Rural Crisis Center | Unclassified | $2.5M | $3.9M |
| 65 | Mid-missouri Legal Services Corporation | Unclassified | $2.5M | $15.4M |
| 66 | Foundaton for the Higher Good INC | Philanthropy, Voluntarism & Grantmaking | $2.4M | $1.7M |
| 67 | United Community Builders Community Development Corporation | Human Services | $2.3M | $7.6M |
| 68 | Proctor Mulligan Foundation Tr 070902 | Philanthropy, Voluntarism & Grantmaking | $2.3M | $7.0M |
| 69 | Missouri Pork Producers Association | Employment | $2.2M | $4.8M |
| 70 | Columbia Center for Urban Agriculture | Environment | $2.2M | $3.5M |
| 71 | Missouri Cattlemens Association | Unclassified | $2.0M | $751K |
| 72 | Ragtag Film Society | Arts, Culture & Humanities | $2.0M | $490K |
| 73 | First Baptist Church Trust | Philanthropy, Voluntarism & Grantmaking | $2.0M | $4.2M |
| 74 | Missouri Fam Tr | Health Care | $1.9M | $3.7M |
| 75 | Knowledge Management Associates | Health Care | $1.9M | $1.1M |
| 76 | Fostering Life-changing Opportunities | Human Services | $1.9M | $4.4M |
| 77 | Alpha Phi House Corporation Board- University of Missouri | Unclassified | $1.9M | $14.8M |
| 78 | Boyd Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.8M | $1.3M |
| 79 | Missouri Immunization Coalition | Health Care | $1.8M | $536K |
| 80 | Charitable Trust of the Missouri Family Trust | Health Care | $1.8M | $5.2M |
| 81 | Center for Excellence in Health Care Journalism | Community Improvement & Capacity Building | $1.8M | $2.2M |
| 82 | Boys and Girls Clubs of the Columbia Area | Youth Development | $1.7M | $3.6M |
| 83 | Kappa Kappa Gamma House Corp of Columbia | Unclassified | $1.6M | $7.4M |
| 84 | The Rainbow Network INC | Health Care | $1.6M | $2.8M |
| 85 | Finis M Moss Charitable Trust | Unclassified | $1.6M | $4.4M |
| 86 | Columbia Chamber of Commerce | Unclassified | $1.6M | $1.6M |
| 87 | Beta Theta Pi Fraternity | Unclassified | $1.5M | $114K |
| 88 | Missouri Food Bank Association | Food, Agriculture & Nutrition | $1.5M | $3.3M |
| 89 | Gamma Phi Beta Sorority INC | Unclassified | $1.5M | $8.5M |
| 90 | Pet Missouri - Columbia INC | Human Services | $1.4M | $2.1M |
| 91 | Kappa Delta Epsilon Iota House Corp. | Unclassified | $1.4M | $6.7M |
| 92 | Rho Alpha of Chi Omega INC | Unclassified | $1.4M | $4.5M |
| 93 | Veterinary Cancer Society | Education | $1.4M | $3.3M |
| 94 | Missourian Publishing Assn INC | Education | $1.4M | $160K |
| 95 | Chi Mi Alumni Association | Unclassified | $1.4M | $411K |
| 96 | Alpha Gamma Chapter of Alpha Delta Pi House Corp. | Unclassified | $1.3M | $2.2M |
| 97 | Delta Upsilon Fraternity | Unclassified | $1.3M | $511K |
| 98 | Giving Branch Foundation | Philanthropy, Voluntarism & Grantmaking | $1.3M | $768K |
| 99 | William Guitar Little Charitable Fund | Philanthropy, Voluntarism & Grantmaking | $1.3M | $4.7M |
| 100 | Renew Missouri Advocates | Environment | $1.2M | $826K |