| 1 | Midcontinent Independent System Operator INC | Public & Societal Benefit | $616.4M | $3.4B |
| 2 | Police and Firemens Insurance Association | Unclassified | $98.7M | $308.3M |
| 3 | Deborah Joy Simon Foundation | Philanthropy, Voluntarism & Grantmaking | $79.6M | $86.4M |
| 4 | Liberty Fund INC | Unclassified | $69.6M | $396.6M |
| 5 | Zeta Tau Alpha Fraternity | Unclassified | $59.0M | $13.9M |
| 6 | Affordable Housing Partners INC | Housing & Shelter | $43.1M | $413.5M |
| 7 | Central Indiana School Employees Insurence Tr | Unclassified | $37.3M | $17.3M |
| 8 | Indiana Secondary Market for Education Loans INC | Public & Societal Benefit | $34.7M | $241.4M |
| 9 | Samerian Foundation INC | Philanthropy, Voluntarism & Grantmaking | $33.2M | $69.3M |
| 10 | International Brotherhood of Teamsters | Employment | $30.9M | $6.2M |
| 11 | Southeastern Indiana School Insurance Trust | Mutual & Membership Benefit | $28.5M | $11.3M |
| 12 | Little Star Center INC | Education | $26.6M | $5.9M |
| 13 | Tom and Julie Wood Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $26.2M | $32.6M |
| 14 | Hatch INC | Food, Agriculture & Nutrition | $26.1M | $1.6M |
| 15 | Sol Foundation INC | Philanthropy, Voluntarism & Grantmaking | $25.0M | $24.9M |
| 16 | Zeta Tau Alpha Foundation INC | Education | $21.7M | $33.2M |
| 17 | Zeta Tau Alpha Fraternity Housing Corpation | Recreation & Sports | $21.1M | $93.5M |
| 18 | Zeta Tau Alpha Intl Fraternity & Fraternity Housing Corporation | Unclassified | $17.9M | $37.7M |
| 19 | Sigma Kappa National Housing Corp. | Unclassified | $14.9M | $45.0M |
| 20 | Clven National House Corporation | Education | $12.7M | $8.0M |
| 21 | Smith Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $12.6M | $43.7M |
| 22 | National Precast Concrete Association INC | Unclassified | $12.4M | $16.5M |
| 23 | University High School of Indiana INC | Education | $12.2M | $15.8M |
| 24 | Sigma Kappa Sorority | Unclassified | $10.1M | $14.9M |
| 25 | Indiana Statewide Association of Rural Electrics Cooperatives INC | Unclassified | $10.0M | $10.7M |
| 26 | The Center for the Performing Arts INC | Arts, Culture & Humanities | $9.8M | $15.2M |
| 27 | Lambda Chi Alpha Educational Foundation INC | Education | $9.7M | $20.8M |
| 28 | Nicholas H Noyes Jr Memorial Foundation INC | Unclassified | $9.3M | $133.1M |
| 29 | Woodland Country Club | Unclassified | $9.1M | $15.0M |
| 30 | Hamilton County Tourism INC | Unclassified | $8.7M | $5.6M |
| 31 | Thurston Foundation INC | Unclassified | $8.2M | $18.1M |
| 32 | Lambda Chi Alpha Fraternity INC | Unclassified | $7.8M | $6.7M |
| 33 | Crooked Stick Golf Club INC | Unclassified | $7.8M | $20.2M |
| 34 | Cook Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $7.7M | $9.5M |
| 35 | Boilermaker Alliance INC | Community Improvement & Capacity Building | $7.6M | $3.2M |
| 36 | Indiana Lions Eye Bank INC | Unclassified | $7.5M | $17.8M |
| 37 | Radiant Communities Development Corporation | Housing & Shelter | $7.0M | $12.7M |
| 38 | Arthur Jordan Foundation | Unclassified | $6.6M | $19.0M |
| 39 | Fidelis Center for Law and Policy | Civil Rights, Social Action & Advocacy | $6.6M | $3.2M |
| 40 | Theta Chi Fraternity INC | Unclassified | $6.4M | $2.2M |
| 41 | Schwarz Family Foundation | Philanthropy, Voluntarism & Grantmaking | $6.3M | $8.0M |
| 42 | National Electrical Manufacturers Representatives Association | Unclassified | $6.0M | $4.5M |
| 43 | National Panhellenic Conference INC | Unclassified | $5.8M | $3.8M |
| 44 | United Food and Commercial Workers International Union | Unclassified | $5.7M | $1.0M |
| 45 | Mara Elephant Project USA INC | Philanthropy, Voluntarism & Grantmaking | $5.7M | $4.1M |
| 46 | Alpha Sigma Phi Fraternity INC | Unclassified | $5.2M | $3.0M |
| 47 | Gerald and Adele Kraft Charitable Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $5.1M | $5.1M |
| 48 | Little Buns INC | Education | $4.7M | $1.1M |
| 49 | Arrow Consultation Services INC | Mental Health & Crisis Intervention | $4.7M | $2.5M |
| 50 | Carmel Dads Club INC | Youth Development | $4.6M | $7.7M |
| 51 | Fidelis | Religion-Related | $4.5M | $2.9M |
| 52 | Zeta Beta Tau Foundation INC | Education | $4.3M | $12.4M |
| 53 | Great American Songbook Foundation INC | Arts, Culture & Humanities | $4.3M | $8.6M |
| 54 | National Electrical Contractors Association INC | Unclassified | $4.0M | $8.3M |
| 55 | Monument Charitable INC | Philanthropy, Voluntarism & Grantmaking | $4.0M | $3.8M |
| 56 | Neurosurgery Foundation at Goodman Campbell INC | Medical Research | $4.0M | $7.2M |
| 57 | Childrens Theraplay Foundation INC | Health Care | $3.9M | $7.2M |
| 58 | Discipledata INC | Religion-Related | $3.9M | $1.4M |
| 59 | Carmel Midtown Community Development Corporation | Community Improvement & Capacity Building | $3.6M | $15.0M |
| 60 | The Booth Tarkington Civic Theatre INC | Unclassified | $3.1M | $2.0M |
| 61 | Carmel Christkindlmarkt INC | Arts, Culture & Humanities | $3.1M | $2.2M |
| 62 | Sigma Tau Gamma Fraternity | Unclassified | $3.1M | $3.0M |
| 63 | Reese Family Foundation for Christ INC | Philanthropy, Voluntarism & Grantmaking | $3.0M | $967K |
| 64 | Human Concern US INC | International, Foreign Affairs & National Security | $2.9M | $859K |
| 65 | Partnership for Afforable Housing INC | Housing & Shelter | $2.8M | $13.4M |
| 66 | Carmel Swim Club | Unclassified | $2.7M | $4.9M |
| 67 | Sigma Delta Tau Society | Unclassified | $2.6M | $5.7M |
| 68 | Midwest Academy INC | Unclassified | $2.6M | $4.9M |
| 69 | Zeta Beta Tau Fraternity | Unclassified | $2.6M | $2.6M |
| 70 | Autism Society of America | Diseases, Disorders & Medical Disciplines | $2.5M | $660K |
| 71 | Sigma Kappa Foundation INC | Education | $2.5M | $12.1M |
| 72 | P Kent Hawryluk Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $2.4M | $2.0M |
| 73 | Indiana Agriculture Education INC | Education | $2.4M | $1.1M |
| 74 | Foundation Chapter of Theta Chi Fraternity INC | Unclassified | $2.4M | $18.4M |
| 75 | Coram Deo Academy INC | Education | $2.3M | $1.1M |
| 76 | Thoman Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.1M | $5.6M |
| 77 | Indianapolis Youth Hockey Association INC | Recreation & Sports | $2.1M | $610K |
| 78 | Hamilton County Economic Development Corporation | Unclassified | $2.1M | $371K |
| 79 | Digital Pathology Association INC | Community Improvement & Capacity Building | $2.0M | $3.8M |
| 80 | Sigma Delta Tau Foundation INC | Education | $1.9M | $1.7M |
| 81 | Acacia Fraternity Foundation INC | Education | $1.9M | $6.8M |
| 82 | Trinity Free Clinic INC | Health Care | $1.9M | $1.5M |
| 83 | Indiana Optometric Association INC | Unclassified | $1.8M | $3.3M |
| 84 | Howdy Doody Good Times Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.8M | $3.5M |
| 85 | Independent Insurance Agents of Indiana INC | Unclassified | $1.7M | $4.1M |
| 86 | Alpha Sigma Phi Foundation INC | Education | $1.6M | $15.6M |
| 87 | Indy Latin School Association INC | Education | $1.6M | $3.3M |
| 88 | Cohen Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.6M | $4.5M |
| 89 | Quality 360 Healthcare Alliance | Health Care | $1.5M | $79K |
| 90 | Indiana Broadcasters Association INC | Unclassified | $1.5M | $3.1M |
| 91 | Shaheen Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.5M | $2.4M |
| 92 | Sigma Kappa National Housing Corporation | Unclassified | $1.4M | $35.1M |
| 93 | Dunn Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.4M | $2.8M |
| 94 | Indiana Mineral Aggregates Association INC | Unclassified | $1.4M | $1.9M |
| 95 | Ascent 121 INC | Human Services | $1.4M | $1.9M |
| 96 | Indy Hematology Education INC | Diseases, Disorders & Medical Disciplines | $1.4M | $2.0M |
| 97 | Pattern | Community Improvement & Capacity Building | $1.4M | $816K |
| 98 | Michael F Petrie and Jody J Petrie Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $5.2M |
| 99 | Weaver Popcorn Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.2M | $1.9M |
| 100 | Acacia Fraternity Incorporated | Unclassified | $1.2M | $389K |