| 1 | Sarah Bush Lincoln Health Center | Health Care | $747.5M | $1.2B |
| 2 | Heartland Health System INC | Health Care | $44.2M | $65.1M |
| 3 | Coles-moultrie Electric Cooperative | Unclassified | $32.7M | $66.1M |
| 4 | Sarah Bush Lincoln Health System INC | Health Care | $20.0M | $67.2M |
| 5 | The Lumpkin Family Foundation | Unclassified | $15.9M | $39.9M |
| 6 | Independent Order of Odd Fellows | Health Care | $12.9M | $10.3M |
| 7 | Coles County Mental Health Association INC | Mental Health & Crisis Intervention | $6.5M | $5.9M |
| 8 | Sarah Bush Lincoln Health Foundation | Unclassified | $6.4M | $32.2M |
| 9 | Oberlin Charitable Trust | Education | $5.8M | $4.9M |
| 10 | Mattoon Area Young Mens Christian Association | Human Services | $3.1M | $13.9M |
| 11 | Lake Land College Foundation INC | Education | $2.5M | $19.5M |
| 12 | Clear Water Service Corporation | Unclassified | $2.1M | $5.8M |
| 13 | Mattoon Golf & Country Club | Unclassified | $1.8M | $1.4M |
| 14 | Area Educational Credit Union | Unclassified | $1.4M | $30.1M |
| 15 | Sparks Foundation | Philanthropy, Voluntarism & Grantmaking | $1.3M | $1.8M |
| 16 | Mattoon Sports Complex INC | Community Improvement & Capacity Building | $1.3M | $36.9M |
| 17 | Howell-adams Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $2.5M |
| 18 | Douglas-hart Foundation | Unclassified | $1.2M | $5.2M |
| 19 | First Bancshares INC | Unclassified | $728K | $610K |
| 20 | Camp New Hope INC | Unclassified | $684K | $2.8M |
| 21 | Blaw Knox Credit Union | Unclassified | $671K | $12.9M |
| 22 | Sarah Bush Lincoln Health Center Guild | Health Care | $659K | $403K |
| 23 | Coles Together | Unclassified | $614K | $2.6M |
| 24 | Habitat for Humanity International INC | Unclassified | $492K | $2.0M |
| 25 | Mercedes Hoag Charitable Trust No 89135 | Unclassified | $481K | $757K |
| 26 | Jacob Stump Jr and Clara Stump Memorial Scholarship Fund | Unclassified | $410K | $696K |
| 27 | Anna B Welch Memorial Trust | Unclassified | $382K | $1.1M |
| 28 | Mattoon Lodge 803 Loyal Order of Moose | Unclassified | $353K | $560K |
| 29 | Veterans of Foreign Wars Department of Illinois | Unclassified | $347K | $1.3M |
| 30 | Arthur a and Bessie E Perry Memorial Trust | Unclassified | $331K | $462K |
| 31 | Mattoon Community Food Center | Food, Agriculture & Nutrition | $303K | $243K |
| 32 | Courtyard Square INC | Housing & Shelter | $273K | $1.1M |
| 33 | Barger Family Charitable Foundation Tr | Education | $263K | $205K |
| 34 | Fraternal Order of Eagles | Mutual & Membership Benefit | $260K | $863K |
| 35 | Mattoon Area Pads Community Organization | Housing & Shelter | $242K | $707K |
| 36 | Mattoon Cobra Softball | Recreation & Sports | $236K | $384K |
| 37 | The Mission House INC | Human Services | $221K | $481K |
| 38 | Mattoon Chamber of Commerce | Unclassified | $219K | $437K |
| 39 | American Legion | Unclassified | $217K | $865K |
| 40 | United Way of Coles County INC | Philanthropy, Voluntarism & Grantmaking | $195K | $147K |
| 41 | Elevate Ccic INC | Employment | $194K | $114K |
| 42 | Mattoon Baseball Club INC | Recreation & Sports | $185K | $99K |
| 43 | Rotary International | Unclassified | $179K | $249K |
| 44 | Mattoon Pride Softball INC | Recreation & Sports | $172K | $123K |
| 45 | Ruth a Apperson Decd Trust Uw First Natl Bank Ttee | Unclassified | $167K | $826K |
| 46 | J Logan Gover Family Scholarship Fund | Philanthropy, Voluntarism & Grantmaking | $167K | $967K |
| 47 | Coles County Mental Health Residential Alternatives INC | Unclassified | $152K | $171K |
| 48 | St. Mary House | Housing & Shelter | $141K | $445K |
| 49 | First General Baptist Church of Mattoon | Unclassified | $135K | $1 |
| 50 | Mattoon in Motion INC | Unclassified | $127K | $77K |
| 51 | Beyond US Ministries | Education | $106K | $490K |
| 52 | Elizabeth Cornelia Waggoner Tr | Philanthropy, Voluntarism & Grantmaking | $106K | $341K |
| 53 | Mary Ellen Defenbaugh Charitable Tr | Education | $91K | $499K |
| 54 | Fit-2-serve INC | Religion-Related | $89K | $217K |
| 55 | Family Motor Coach Association | Unclassified | $88K | $112K |
| 56 | William E & Myrtle a Jones Scholarship Trust | Unclassified | $79K | $194K |
| 57 | Asymmetric Biodiversity Studies &observation Group Nfp | Science & Technology | $75K | $1.6M |
| 58 | Mattoon Junior Baseball INC | Recreation & Sports | $73K | $103K |
| 59 | Mattoon Community Trust | Unclassified | $57K | $282K |
| 60 | Policemens Benevolent & Protective Association | Unclassified | $55K | $36K |
| 61 | International Union United Auto Aerospace Agricultural Workers | Unclassified | $50K | $71K |
| 62 | Sexson Memorial Music Scholarship Fund | Education | $41K | $127K |
| 63 | Irene Storey Scholarship Fund | Unclassified | $24K | $77K |
| 64 | Illinois Entrepreneurship and Small Business Growth Association | Arts, Culture & Humanities | $24K | $35K |
| 65 | Myrna M Johnson Memorial Trust Scholarship Fund | Unclassified | $23K | $27K |
| 66 | James a Ridge Assumption Beautification Tr | Unclassified | $18K | $80K |
| 67 | J Leonard Brown Memorial Schlrsp Tr | Philanthropy, Voluntarism & Grantmaking | $16K | $71K |
| 68 | Coles County Historical Society | Arts, Culture & Humanities | $15K | $191K |
| 69 | Mattoon Golf & Country Club Historical Preservation Foundation | Arts, Culture & Humanities | $14K | $24K |
| 70 | Florence M Ramsey Memorial Scholarship Trust | Education | $3K | $60K |
| 71 | Russell C and Sylvia B Swinehart Scholarship Fund | Education | $3K | $19K |
| 72 | Coles County Community Christian Center | Human Services | $0 | $0 |
| 73 | New Mercy Worship Center | Religion-Related | $0 | $0 |
| 74 | Department of Illinois VFW Auxiliary INC | Public & Societal Benefit | $0 | $0 |
| 75 | Order of the Eastern Star of Illinois | Unclassified | $0 | $0 |
| 76 | Lake Land Church of Christ | Unclassified | $0 | $0 |
| 77 | American Federation of Teachers | Unclassified | $0 | $0 |
| 78 | Coles County Humane Association INC | Animal-Related | $0 | $0 |
| 79 | Family Motor Coach Association | Unclassified | $0 | $0 |
| 80 | Mattoon Firefighters Charitable Program | Public & Societal Benefit | $0 | $0 |
| 81 | Life Pointe Church INC | Religion-Related | $0 | $0 |
| 82 | Champaign County Extension Education Foundation | Youth Development | $0 | $0 |
| 83 | Genesis Animal Rescue & Rehabilitation Charity INC Nfo | Animal-Related | $0 | $0 |
| 84 | Champaign County Extension Education Foundation | Youth Development | $0 | $0 |
| 85 | Ancient Free & Accepted Masons of Illinois | Unclassified | $0 | $0 |
| 86 | Knights of Columbus | Unclassified | $0 | $0 |
| 87 | First Baptist Church | Unclassified | $0 | $0 |
| 88 | First Christian Church Marilyn Purcell | Religion-Related | $0 | $0 |
| 89 | Saint Johns Lutheran Church | Unclassified | $0 | $0 |
| 90 | Saint Paul Lutheran Church | Unclassified | $0 | $0 |
| 91 | Broadway-christian Church | Religion-Related | $0 | $0 |
| 92 | The Fields Church | Unclassified | $0 | $0 |
| 93 | Mattoon First Church of the Nazarene | Unclassified | $0 | $0 |
| 94 | Mattoon East Side Church of the Nazarene | Unclassified | $0 | $0 |
| 95 | Mattoon Chapt No 312 Women of the Moose | Unclassified | $0 | $0 |
| 96 | United Steelworkers | Unclassified | $0 | $0 |
| 97 | Coles County Extention Foundation 703 Monroe St. | Youth Development | $0 | $0 |
| 98 | Rotary International | Unclassified | $0 | $0 |
| 99 | First Southern Baptist Church of Mattoon | Unclassified | $0 | $0 |
| 100 | Knights of Columbus | Unclassified | $0 | $0 |