| 1 | Island Water Association INC | Unclassified | $18.4M | $39.4M |
| 2 | Sanibel-captiva Conservation Foundation INC | Environment | $14.0M | $56.9M |
| 3 | Ding Darling Wildlife Society INC | Animal-Related | $5.6M | $27.4M |
| 4 | Clinic for the Rehabilitation of Wildlife INC | Animal-Related | $4.1M | $12.2M |
| 5 | Fish of Sanibel-captiva INC | Human Services | $4.0M | $9.3M |
| 6 | David S Baum Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.1M | $7.0M |
| 7 | Shell Museum and Educational Foundation INC | Arts, Culture & Humanities | $2.8M | $15.0M |
| 8 | Barrier Island Group for the Arts | Arts, Culture & Humanities | $2.6M | $9.5M |
| 9 | Sommers Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.5M | $4.2M |
| 10 | Community Housing and Resources INC | Housing & Shelter | $2.4M | $9.0M |
| 11 | Network for Animals USA INC | Animal-Related | $2.1M | $1.1M |
| 12 | William R Gruver Foundation | Unclassified | $1.4M | $5.0M |
| 13 | Charitable Foundation of the Islands INC | Community Improvement & Capacity Building | $1.3M | $7.8M |
| 14 | Lindsey Davis Charities | Human Services | $1.1M | $1.3M |
| 15 | Sanctuary Golf Club Foundation INC | Philanthropy, Voluntarism & Grantmaking | $912K | $465K |
| 16 | Sanibel Community Association INC | Recreation & Sports | $875K | $5.3M |
| 17 | Animal Survival International USA INC | Animal-Related | $864K | $645K |
| 18 | Sanibel Public Library Foundation INC | Education | $776K | $3.8M |
| 19 | Hafener Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $735K | $1.7M |
| 20 | Childrens Education Center of the Islands INC | Unclassified | $678K | $1.3M |
| 21 | Ora Kathleen Flynn-barnett Foundation | Civil Rights, Social Action & Advocacy | $644K | $754K |
| 22 | Sanibel Captiva Islands Chamber of Commerce INC | Community Improvement & Capacity Building | $566K | $721K |
| 23 | Sanibel & Captiva Islands Association of Realtors INC | Unclassified | $509K | $1.7M |
| 24 | Joseph & Carolyn Palchak Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $421K | $303K |
| 25 | The Sanibel Historical Museum and Village INC | Arts, Culture & Humanities | $349K | $1.6M |
| 26 | Sanibel Captiva Rotary Trust Fund | Unclassified | $344K | $43K |
| 27 | Daniel P Hagerman Foundation | Philanthropy, Voluntarism & Grantmaking | $284K | $247K |
| 28 | F I S H of Sanibel-captiva Foundation INC | Human Services | $245K | $896K |
| 29 | Power of a Nickel INC | Health Care | $239K | $359K |
| 30 | Brookes Foundation | Philanthropy, Voluntarism & Grantmaking | $234K | $1.6M |
| 31 | Joseph a Courter Memorial Scholarship Fund | Philanthropy, Voluntarism & Grantmaking | $229K | $586K |
| 32 | Bpn Foundation - USA | International, Foreign Affairs & National Security | $217K | $138K |
| 33 | Rotary International | Unclassified | $212K | $49K |
| 34 | Rockin Christmas Fund INC | Philanthropy, Voluntarism & Grantmaking | $187K | $1.4M |
| 35 | Smith Share Foundation INC | Philanthropy, Voluntarism & Grantmaking | $163K | $194K |
| 36 | Southwest Florida Care Services for Christian Scientists INC | Health Care | $150K | $25K |
| 37 | Sanibel Music Festival INC | Arts, Culture & Humanities | $102K | $434K |
| 38 | PTA Florida Congress | Unclassified | $102K | $110K |
| 39 | Zonta Foundation of Southwest Florida INC | Education | $83K | $116K |
| 40 | Carmen & Jim Courter Foundation INC | Philanthropy, Voluntarism & Grantmaking | $64K | $123K |
| 41 | Missionary Enterprises INC | Religion-Related | $63K | $609K |
| 42 | Adopt a Stray INC | Animal-Related | $62K | $75K |
| 43 | Gimme Foundation INC | Philanthropy, Voluntarism & Grantmaking | $58K | $60K |
| 44 | McGrath-spellman Family Foundation | Philanthropy, Voluntarism & Grantmaking | $36K | $956K |
| 45 | Nicholas Gonzalez Foundation | Diseases, Disorders & Medical Disciplines | $35K | $49K |
| 46 | Yvonne and Phillip Dressel Foundation | Philanthropy, Voluntarism & Grantmaking | $28K | $139K |
| 47 | Kingfisher Charitable Trust INC | Animal-Related | $25K | $16K |
| 48 | Kaltenmark Family Foundation INC | Human Services | $22K | $84K |
| 49 | Steve & Lena Brown Family Fndn | Philanthropy, Voluntarism & Grantmaking | $20K | $1 |
| 50 | Sunrise Foundation | Philanthropy, Voluntarism & Grantmaking | $20K | $321K |
| 51 | Spoken Word Foundation | Religion-Related | $15K | $320 |
| 52 | Grace Fleming Reinhold Scholarship Trust | Unclassified | $663 | $58K |
| 53 | Joann and Bob Glick Foundation | Philanthropy, Voluntarism & Grantmaking | $277 | $6K |
| 54 | International Federation of Fly Fishers INC | Unclassified | $0 | $0 |
| 55 | Sanibel-captiva Art League INC | Arts, Culture & Humanities | $0 | $0 |
| 56 | United States Power Squadrons | Unclassified | $0 | $0 |
| 57 | Sports Heritage Network INC | Education | $0 | $0 |
| 58 | Coast and Islands Community Landtrust INC | Housing & Shelter | $0 | $1 |
| 59 | Sanibel Bicycle Club INC | Recreation & Sports | $0 | $0 |
| 60 | Lee Coast Chapter of the Military Officers Assoc of Amer Fdn INC | Public & Societal Benefit | $0 | $0 |
| 61 | American Legion Auxiliary | Unclassified | $0 | $0 |
| 62 | Sanibel-captiva Kiwanis Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 63 | Keenans Kids INC | International, Foreign Affairs & National Security | $0 | $0 |
| 64 | Catherine Ross Fund | Human Services | $0 | $0 |
| 65 | Owens Family Charitable Foundation INC | Housing & Shelter | $0 | $0 |
| 66 | Animal Survival International INC | Animal-Related | $0 | $0 |
| 67 | Lee Coast Chapter of the Military Officers Association of America | Mutual & Membership Benefit | $0 | $0 |
| 68 | US Lacrosse INC | Unclassified | $0 | $0 |
| 69 | Bnai Israel & Greater Miami Youth Synagogue INC | Unclassified | $0 | $0 |
| 70 | Sanibel-captiva Shell Club INC | Environment | $0 | $0 |
| 71 | The International Osprey Foundation INC | Unclassified | $0 | $0 |
| 72 | St. Michael and All Angels Episcopal Church | Unclassified | $0 | $0 |
| 73 | Condominium Associations of Sanibel INC | Unclassified | $0 | $0 |
| 74 | Sanibel Congregational United Church of Christ INC | Unclassified | $0 | $0 |
| 75 | Sanibel Community Church | Religion-Related | $0 | $0 |
| 76 | Protection of Animal Welfare Society INC P a W S INC | Unclassified | $0 | $0 |
| 77 | Zonta International | Unclassified | $0 | $0 |
| 78 | Bat Yam Temple of the Islands INC | Unclassified | $0 | $0 |
| 79 | Island Seniors INC | Unclassified | $0 | $0 |
| 80 | The Sanibel-captiva Audubon Society INC | Environment | $0 | $0 |
| 81 | Sanibel-captiva Lions Charities INC | Philanthropy, Voluntarism & Grantmaking | $0 | $0 |
| 82 | Lee County Artificial Reef Association INC | Environment | $0 | $0 |
| 83 | Sanibel Island Fishing Club INC | Recreation & Sports | $0 | $0 |
| 84 | From Within | Mental Health & Crisis Intervention | $0 | $0 |
| 85 | Furnish with Care | Housing & Shelter | $0 | $0 |
| 86 | San Cap Pink Project INC | Medical Research | $0 | $0 |
| 87 | Now I Know INC | Education | $0 | $0 |
| 88 | Health Equity Consulting INC | Medical Research | $0 | $0 |