| 1 | Naples Community Hospital INC | Health Care | $988.4M | $1.2B |
| 2 | The Moorings Incorporated | Human Services | $643.1M | $1.2B |
| 3 | Schoen Foundation | Unclassified | $479.4M | $412.0M |
| 4 | Nchmd INC | Health Care | $134.7M | $131.0M |
| 5 | Collier Community Foundation INC | Unclassified | $106.7M | $287.5M |
| 6 | Port Royal Club INC | Unclassified | $82.5M | $104.9M |
| 7 | David Lawrence Mental Health Center INC | Mental Health & Crisis Intervention | $67.1M | $57.8M |
| 8 | Naples Children and Education | Philanthropy, Voluntarism & Grantmaking | $61.5M | $105.6M |
| 9 | St. Matthews House INC | Housing & Shelter | $60.2M | $64.0M |
| 10 | Artis-naples INC | Arts, Culture & Humanities | $57.2M | $274.0M |
| 11 | Hope for Haiti INC | International, Foreign Affairs & National Security | $54.5M | $9.3M |
| 12 | Cloverfields Foundation | Philanthropy, Voluntarism & Grantmaking | $48.8M | $58.4M |
| 13 | Habitat for Humanity of Collier County INC | Housing & Shelter | $46.9M | $138.9M |
| 14 | Banyan Gate Foundation | Philanthropy, Voluntarism & Grantmaking | $42.9M | $44.7M |
| 15 | Mill Park Foundation | Philanthropy, Voluntarism & Grantmaking | $41.2M | $61.7M |
| 16 | Wyndemere Country Club INC | Unclassified | $40.5M | $53.7M |
| 17 | Community School of Naples INC | Education | $38.3M | $96.4M |
| 18 | Adams Family Foundation | Philanthropy, Voluntarism & Grantmaking | $36.4M | $57.9M |
| 19 | Avow Hospice INC | Human Services | $35.2M | $41.6M |
| 20 | Baker Family Foundation | Philanthropy, Voluntarism & Grantmaking | $31.3M | $31.4M |
| 21 | Ahuja Charitable Foundation | Unclassified | $28.7M | $47.3M |
| 22 | Boys & Girls Club of Collier County INC | Youth Development | $28.7M | $49.5M |
| 23 | Naples Botanical Garden INC | Environment | $28.6M | $74.0M |
| 24 | Bruce and Deborah Duncan Foundation | Philanthropy, Voluntarism & Grantmaking | $28.0M | $39.0M |
| 25 | Royal Poinciana Golf Club INC | Unclassified | $27.3M | $79.8M |
| 26 | William T Morris Foundation INC | Unclassified | $26.9M | $36.1M |
| 27 | Gate Golf Club INC | Recreation & Sports | $25.6M | $15.1M |
| 28 | The Conservancy of Southwest Florida INC | Unclassified | $25.5M | $100.5M |
| 29 | The Club at Mediterra INC | Recreation & Sports | $25.1M | $78.8M |
| 30 | Elaine Nicpon Marieb Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $25.1M | $60.3M |
| 31 | Twineagles Club INC | Recreation & Sports | $25.0M | $75.0M |
| 32 | John P and Anne Welsh McNulty Foundation | Unclassified | $24.4M | $42.0M |
| 33 | Foundation for Government Accountability INC | Public & Societal Benefit | $24.3M | $16.9M |
| 34 | Johnson Fam Foundation | Philanthropy, Voluntarism & Grantmaking | $24.2M | $11.4M |
| 35 | Armstrong Foundation INC | Philanthropy, Voluntarism & Grantmaking | $23.3M | $36.1M |
| 36 | Belford Family Charitable Fund INC | Philanthropy, Voluntarism & Grantmaking | $23.3M | $37.8M |
| 37 | Ave Maria School of Law | Education | $23.0M | $19.5M |
| 38 | The Club at Pelican Bay INC | Unclassified | $22.6M | $50.3M |
| 39 | The Shelter for Abused Women & Children INC | Human Services | $21.5M | $72.8M |
| 40 | Better Together Strengthening Families INC | Human Services | $20.4M | $34.8M |
| 41 | Mason Classical Academy INC | Education | $19.4M | $23.3M |
| 42 | Quarry Golf Club INC | Recreation & Sports | $18.8M | $25.2M |
| 43 | Telford Foundation INC | Philanthropy, Voluntarism & Grantmaking | $17.6M | $74.6M |
| 44 | J & J Family Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $17.4M | $27.2M |
| 45 | Starability Foundation INC | Philanthropy, Voluntarism & Grantmaking | $17.3M | $29.6M |
| 46 | Clay and Debbiejones Family Foundation | Philanthropy, Voluntarism & Grantmaking | $17.1M | $18.4M |
| 47 | Gulfshore Playhouse INC | Arts, Culture & Humanities | $17.0M | $80.8M |
| 48 | Quail Creek Country Club INC | Unclassified | $16.9M | $46.9M |
| 49 | William S Knight Foundation INC | Religion-Related | $15.8M | $39.0M |
| 50 | Ray Foundation INC | Unclassified | $15.6M | $66.9M |
| 51 | Martin Foundation INC | Unclassified | $15.4M | $38.7M |
| 52 | Naples Yacht Club INC | Unclassified | $15.2M | $28.0M |
| 53 | Meals of Hope INC | Food, Agriculture & Nutrition | $14.4M | $5.4M |
| 54 | Village School of Naples INC | Education | $14.2M | $6.2M |
| 55 | Bonus Fund | Philanthropy, Voluntarism & Grantmaking | $14.0M | $14.9M |
| 56 | Avow Foundation INC | Health Care | $13.5M | $59.4M |
| 57 | Royal Palm Academy INC | Human Services | $13.4M | $9.0M |
| 58 | Bay Colony Golf Club INC | Recreation & Sports | $13.3M | $37.2M |
| 59 | Seacrest School INC | Education | $13.2M | $29.8M |
| 60 | Naples Zoo INC | Animal-Related | $13.1M | $42.8M |
| 61 | Phoenix Education Network INC | Education | $12.8M | $27.7M |
| 62 | Moorings Park Community Health Incorporated | Housing & Shelter | $12.8M | $2.1M |
| 63 | Harder Foundation | Unclassified | $12.7M | $36.2M |
| 64 | The Byrnes Family Foundation | Unclassified | $12.6M | $19.3M |
| 65 | Moorings Park Institute Incorporated | Housing & Shelter | $12.6M | $164.4M |
| 66 | The Revs Institute INC | Education | $12.3M | $29.5M |
| 67 | Reoso Foundation | Human Services | $12.3M | $3.0M |
| 68 | Imperial Golf Club INC | Unclassified | $12.1M | $35.8M |
| 69 | Grace Place for Children and Families INC | Human Services | $12.0M | $18.2M |
| 70 | Youth Haven INC | Human Services | $11.5M | $20.7M |
| 71 | Neighborhood Health Clinic INC | Health Care | $11.5M | $63.3M |
| 72 | YMCA of Collier County INC | Unclassified | $11.2M | $21.2M |
| 73 | Audubon Country Club Association INC | Recreation & Sports | $10.9M | $39.9M |
| 74 | Naples National Golf Club INC | Unclassified | $10.4M | $30.2M |
| 75 | Gulf Coast Charter Academy South INC | Education | $10.2M | $15.8M |
| 76 | Youngquist Family Foundation | Philanthropy, Voluntarism & Grantmaking | $10.0M | $9.3M |
| 77 | The Immokalee Foundation INC | Philanthropy, Voluntarism & Grantmaking | $9.9M | $19.8M |
| 78 | Naples Sailing & Yacht Club INC | Unclassified | $9.6M | $14.8M |
| 79 | Sage & Dice Foundation | Philanthropy, Voluntarism & Grantmaking | $9.2M | $4.4M |
| 80 | Eagle Creek Golf and Country Club INC | Recreation & Sports | $9.2M | $35.9M |
| 81 | Hole-in-the-wall Golf Club INC Frank Road | Unclassified | $9.2M | $23.3M |
| 82 | Wilderness Country Club INC | Unclassified | $9.0M | $34.2M |
| 83 | Country Club of Naples INC | Unclassified | $8.7M | $25.9M |
| 84 | Baker Senior Center Naples INC | Human Services | $8.6M | $22.9M |
| 85 | Summit Foundation INC | Philanthropy, Voluntarism & Grantmaking | $8.3M | $14.5M |
| 86 | Bears Paw Country Club INC | Unclassified | $8.3M | $24.6M |
| 87 | Humane Society of Collier County INC | Animal-Related | $8.2M | $15.0M |
| 88 | Royal Palm Country Club of Naples INC | Unclassified | $7.4M | $15.2M |
| 89 | Paul Jepson Scholarship Foundation | Education | $7.0M | $4.5M |
| 90 | Hasse Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.7M | $7.5M |
| 91 | John and Carol Walter Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.6M | $20.3M |
| 92 | The Education Foundation of Collier County INC | Philanthropy, Voluntarism & Grantmaking | $6.5M | $10.8M |
| 93 | Helen W Bell Charitable Foundation U a D July 22 1982 | Philanthropy, Voluntarism & Grantmaking | $6.5M | $16.1M |
| 94 | Bartley J Madden Foundation | Philanthropy, Voluntarism & Grantmaking | $6.5M | $8.1M |
| 95 | Mark and Lisa Ratner Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.5M | $4.1M |
| 96 | The Naples Players INC | Arts, Culture & Humanities | $6.4M | $36.5M |
| 97 | Riverside at Moorings Park Incorporated | Housing & Shelter | $6.4M | $83.6M |
| 98 | Vanderboom Fam Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $6.3M | $4.8M |
| 99 | Fun Time Early Childhood Academy INC | Human Services | $6.2M | $10.2M |
| 100 | Sg Schimenti Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.2M | $43.5M |