| 1 | Chuck and Marna Davis Foundation | Unclassified | $69.2M | $148.6M |
| 2 | Ocean Reef Foundation INC | Philanthropy, Voluntarism & Grantmaking | $31.7M | $109.7M |
| 3 | Peninsula Charities Foundation II | Philanthropy, Voluntarism & Grantmaking | $19.6M | $26.3M |
| 4 | Ferri Family Foundation | Philanthropy, Voluntarism & Grantmaking | $18.2M | $76.6M |
| 5 | Ocean Reef Chapel Foundation INC | Unclassified | $17.8M | $25.3M |
| 6 | Ocean Reef Medical Center Foundation INC | Unclassified | $16.4M | $67.2M |
| 7 | Ocean Reef Cultural Center INC | Arts, Culture & Humanities | $11.7M | $42.1M |
| 8 | Anglers Club Members Association INC & Subsidiary | Recreation & Sports | $8.5M | $27.9M |
| 9 | The Medical Center at Ocean Reef INC | Unclassified | $7.9M | $1.8M |
| 10 | Marine Resources Development Foundation | Science & Technology | $6.8M | $27.8M |
| 11 | Orcat INC | Animal-Related | $6.2M | $7.4M |
| 12 | Costas Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $5.6M | $5.1M |
| 13 | Reef Environmental Education Foundation Incorporated | Recreation & Sports | $5.3M | $6.9M |
| 14 | North Key Largo Utility Corp. | Unclassified | $4.6M | $20.1M |
| 15 | Davidson Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.4M | $9.6M |
| 16 | Kiphart Family Foundation | Philanthropy, Voluntarism & Grantmaking | $3.4M | $400K |
| 17 | Habitat for Humanity International INC | Housing & Shelter | $3.1M | $14.6M |
| 18 | Morby Family Foundation INC | Unclassified | $2.9M | $23.2M |
| 19 | Academy at Ocean Reef INC | Unclassified | $2.9M | $3.1M |
| 20 | Harrington Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.8M | $7.2M |
| 21 | Key Largo Volunteer Fire Department INC | Public & Societal Benefit | $2.6M | $127K |
| 22 | Dolphins Plus Oceanside Marine Mammal Responder INC | Animal-Related | $2.5M | $3.8M |
| 23 | Ocean Reef Art League INC | Unclassified | $2.4M | $12.3M |
| 24 | Key Largo Volunteer Ambulance Corp INC | Public Safety, Disaster Preparedness & Relief | $1.8M | $774K |
| 25 | John H and Katherine J Weiland Foundation | Philanthropy, Voluntarism & Grantmaking | $1.8M | $4.8M |
| 26 | Morris Willner Family Foundation 06102009 | Philanthropy, Voluntarism & Grantmaking | $1.7M | $774K |
| 27 | Ocean Reef Volunteer Fire Department INC | Public Safety, Disaster Preparedness & Relief | $1.6M | $5.3M |
| 28 | Gayle J & Charles C Tallardy III Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.5M | $2.8M |
| 29 | Slattery Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.3M | $1.3M |
| 30 | Fleet Family Foundation INC | Education | $1.3M | $1.5M |
| 31 | Island Dolphin Care INC | Health Care | $1.0M | $1.5M |
| 32 | Mrm Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $935K | $1.1M |
| 33 | Trust for Trauma Journalism INC | Human Services | $930K | $278K |
| 34 | List Family Foundation | Philanthropy, Voluntarism & Grantmaking | $909K | $3.5M |
| 35 | Keys Advocacy Center INC | Human Services | $822K | $412K |
| 36 | Ocean Reef Yacht Club INC | Unclassified | $712K | $73K |
| 37 | Jasam Foundation Fund a | Philanthropy, Voluntarism & Grantmaking | $686K | $4.5M |
| 38 | Ocean Reef Conservation Association INC | Environment | $680K | $1.6M |
| 39 | Keys Childrens Foundation INC | Human Services | $653K | $462K |
| 40 | Schievelbein Family Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $649K | $1.7M |
| 41 | Strive Foundation INC | Philanthropy, Voluntarism & Grantmaking | $595K | $1.6M |
| 42 | Olsen Family Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $552K | $3.2M |
| 43 | Upper Keys Humane Society INC | Animal-Related | $552K | $1.6M |
| 44 | Key Largo Chamber of Commerce INC | Unclassified | $539K | $501K |
| 45 | Humane Animal Care Coalition INC | Animal-Related | $517K | $978K |
| 46 | Wallace Family Foundation | Philanthropy, Voluntarism & Grantmaking | $458K | $746K |
| 47 | Amercian Legion | Unclassified | $442K | $397K |
| 48 | Key Largo Lodge No 2287 Loyal Order of Moose | Unclassified | $415K | $469K |
| 49 | Bohnert Foundation INC | Philanthropy, Voluntarism & Grantmaking | $398K | $2.5M |
| 50 | Marrvelous Pet Rescues INC | Animal-Related | $379K | $1.2M |
| 51 | Lucas Philip Wintrode Autism Foundation | Education | $379K | $3.7M |
| 52 | Upper Keys Sailing Club INC | Unclassified | $327K | $419K |
| 53 | Reef Rod & Gun Club INC | Recreation & Sports | $255K | $161K |
| 54 | Herman Lucerne Memorial Foundation INC | Recreation & Sports | $238K | $125K |
| 55 | Ocean Reef Chamber of Commerce INC | Community Improvement & Capacity Building | $226K | $174K |
| 56 | Upper Keys Community Pool INC | Recreation & Sports | $213K | $62K |
| 57 | The Key Largo Lions Foundation INC | Medical Research | $197K | $1.9M |
| 58 | Holly Given Fund | Education | $192K | $195K |
| 59 | Deane Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $186K | $524K |
| 60 | Veteran Sailing INC | Public Safety, Disaster Preparedness & Relief | $183K | $625K |
| 61 | Monica D Phillips Foundation INC | Philanthropy, Voluntarism & Grantmaking | $179K | $234K |
| 62 | Mark Sorensen Youth Sailing Programinc | Recreation & Sports | $161K | $90K |
| 63 | Cornerstone Ministries International INC | Religion-Related | $144K | $29K |
| 64 | Rotary Club of Key Largo Charitable Events INC | Unclassified | $142K | $202K |
| 65 | Bonefish Bonnies | Recreation & Sports | $137K | $68K |
| 66 | Florida Keys Board of Realtors INC | Unclassified | $134K | $762K |
| 67 | Greenfield Evangelical Foundation INC | Philanthropy, Voluntarism & Grantmaking | $124K | $2.3M |
| 68 | Friends of John Pennekamp Coral Reef State Park and Dagny Johnson | Environment | $113K | $254K |
| 69 | Mid Keys Officials Association INC | Recreation & Sports | $111K | $13K |
| 70 | Consortium for Waste to Syngas Circularity INC | Unclassified | $109K | $259K |
| 71 | Ypo Ocean Reef Gold INC | Unclassified | $104K | $40K |
| 72 | Pawsitive Beginnings | Animal-Related | $89K | $28K |
| 73 | Rotary Club of Key Largo Sunset Foundation | Human Services | $78K | $100K |
| 74 | Active Disabled Americans INC | Recreation & Sports | $73K | $32K |
| 75 | Card Sound Sailing Club INC C/o Jo Baringer | Unclassified | $70K | $58K |
| 76 | Tatelman Family Foundation | Philanthropy, Voluntarism & Grantmaking | $68K | $9K |
| 77 | Tips Teen Intervention&prevention Services Corp of the Florida Keys | Crime & Legal-Related | $66K | $69K |
| 78 | Rotary International | Unclassified | $57K | $18K |
| 79 | Buttonwood Sound Club INC | Recreation & Sports | $54K | $155K |
| 80 | Orc for Orphans INC | Human Services | $43K | $2K |
| 81 | Hartz Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $38K | $877K |
| 82 | Mark and Eileen Epstein Family Charitable Foundation for Families | Philanthropy, Voluntarism & Grantmaking | $38K | $360 |
| 83 | Barrier Free Divers | Recreation & Sports | $33K | $30K |
| 84 | Hamelin Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $25K | $458K |
| 85 | Ronald D and Carol J Sekura Family Foundation | Philanthropy, Voluntarism & Grantmaking | $15K | $245K |
| 86 | Goldsmith Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $13K | $132K |
| 87 | Cassi INC | Science & Technology | $10K | $29 |
| 88 | Key Largo Community Covenant Church Key Largo Fl | Religion-Related | $8K | $1 |
| 89 | Friends of the Dog Park at Ocean Reef INC | Animal-Related | $7K | $124K |
| 90 | Key Largo Volunteer Fire & Rescue Department INC | Public Safety, Disaster Preparedness & Relief | $4K | $143K |
| 91 | Holmes Family Foundation | Arts, Culture & Humanities | $3K | $365 |
| 92 | Florida Keys Board of Realtors Charitable Trust INC | Public & Societal Benefit | $2K | $59K |
| 93 | The@susan and Bart Shuldman Foundation | Philanthropy, Voluntarism & Grantmaking | $1K | $112K |
| 94 | Artists Environmental Foundation of the Florida Keys INC | Arts, Culture & Humanities | $22 | $21K |
| 95 | Keys Bible Trust INC | Unclassified | $0 | $0 |
| 96 | Veterans of Foreign Wars of the United States Dept of Florida | Unclassified | $0 | $0 |
| 97 | PTA Florida Congress | Unclassified | $0 | $0 |
| 98 | Sons of Italy in America | Unclassified | $0 | $0 |
| 99 | Shiloh Senior Housing INC | Housing & Shelter | $0 | $0 |
| 100 | Key Largo Community Preservation Foundation INC | Environment | $0 | $0 |