| 1 | Jupiter Medical Center INC | Health Care | $484.4M | $594.0M |
| 2 | Kovner Foundation | Philanthropy, Voluntarism & Grantmaking | $94.7M | $335.3M |
| 3 | Jupiter Medical Center Foundation INC | Philanthropy, Voluntarism & Grantmaking | $93.8M | $182.4M |
| 4 | Max Planck Florida Corporation | Medical Research | $33.5M | $108.6M |
| 5 | Jupiter Medical Center Physicians Group INC | Health Care | $31.7M | $17.7M |
| 6 | The Stiles-nicholson Foundation | Unclassified | $29.2M | $60.1M |
| 7 | Jonathans Landing Golf Club INC | Recreation & Sports | $27.0M | $82.6M |
| 8 | Abramson Family Foundation | Philanthropy, Voluntarism & Grantmaking | $23.9M | $20.4M |
| 9 | Jupiter Christian School INC | Unclassified | $23.1M | $21.5M |
| 10 | Els for Autism Foundation | Diseases, Disorders & Medical Disciplines | $21.3M | $60.7M |
| 11 | Phinny Family Foundation | Unclassified | $17.5M | $10.3M |
| 12 | Loxahatchee Club INC | Recreation & Sports | $15.1M | $27.7M |
| 13 | Marni & Morris Propp II Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $14.8M | $16.4M |
| 14 | Maltz Jupiter Theatre INC | Arts, Culture & Humanities | $14.4M | $60.0M |
| 15 | Robert C and Veronica Atkins Foundation | Philanthropy, Voluntarism & Grantmaking | $13.7M | $14.9M |
| 16 | Morris & Anna Propp Sons Fund INC | Unclassified | $13.4M | $15.1M |
| 17 | Drug Abuse Treatment Assc INC | Mental Health & Crisis Intervention | $11.5M | $6.6M |
| 18 | Jas Family Foundation | Philanthropy, Voluntarism & Grantmaking | $11.1M | $17.1M |
| 19 | Furry Friends Humane INC | Animal-Related | $10.1M | $14.6M |
| 20 | Peter Degeorge Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $9.9M | $4.8M |
| 21 | Selfless Love Foundation INC | Human Services | $8.5M | $6.9M |
| 22 | Marieluise Hessel Foundation | Arts, Culture & Humanities | $8.3M | $43.7M |
| 23 | R & M Fink Fam Tr | Education | $8.0M | $16.9M |
| 24 | Kantner Foundation INC | Unclassified | $7.8M | $7.3M |
| 25 | Renaissance Learning Academy INC | Education | $7.3M | $3.2M |
| 26 | David and Melissa Simmons Family Foundation | Philanthropy, Voluntarism & Grantmaking | $6.8M | $19.4M |
| 27 | Great Plains Conservation Foundation | Animal-Related | $5.1M | $7.7M |
| 28 | The Global Self Foundation | Religion-Related | $5.1M | $13.0M |
| 29 | Hearing the Ovarian Cancer Whisper INC | Education | $4.6M | $1.2M |
| 30 | Sam and Karry Meshberg Foundation INC | Philanthropy, Voluntarism & Grantmaking | $4.6M | $5.9M |
| 31 | W III Foundation INC | Philanthropy, Voluntarism & Grantmaking | $4.4M | $11.1M |
| 32 | Ride Well Wheels INC | Health Care | $4.4M | $1.4M |
| 33 | Admirals Cove Foundation INC | Philanthropy, Voluntarism & Grantmaking | $4.3M | $1.4M |
| 34 | The Busch Wildlife Sanctuary INC | Animal-Related | $4.3M | $21.4M |
| 35 | James and Nancy Holmgren Foundation | Philanthropy, Voluntarism & Grantmaking | $3.9M | $6.8M |
| 36 | Eden Charitable Foundation | Unclassified | $3.6M | $6.5M |
| 37 | Jane Beasley Foundation | Philanthropy, Voluntarism & Grantmaking | $3.4M | $2.5M |
| 38 | Hayes Family Foundation | Philanthropy, Voluntarism & Grantmaking | $3.1M | $16.9M |
| 39 | Nicks Kids Foundation INC | Philanthropy, Voluntarism & Grantmaking | $3.0M | $3.3M |
| 40 | Freedom Start Foundation | Philanthropy, Voluntarism & Grantmaking | $2.9M | $3.1M |
| 41 | Maltz Jupiter Theatre Foundation INC | Arts, Culture & Humanities | $2.9M | $13.7M |
| 42 | Lighthouse Artcenter INC | Arts, Culture & Humanities | $2.8M | $5.7M |
| 43 | Ldg & Lpr Charitable Foundation | Human Services | $2.8M | $6.7M |
| 44 | 776 Foundation | Philanthropy, Voluntarism & Grantmaking | $2.8M | $613K |
| 45 | Defined Contribution Institutional Investment Association | Community Improvement & Capacity Building | $2.7M | $2.7M |
| 46 | Boolah Chai Foundation Dtd 12-21-2022 | Public & Societal Benefit | $2.7M | $4.0M |
| 47 | Jupiter Tequesta Athletic | Recreation & Sports | $2.6M | $1.5M |
| 48 | The Salizzoni Family Foundation INC | Education | $2.6M | $5.1M |
| 49 | Eliasburg Family Foundation INC | Unclassified | $2.6M | $8.8M |
| 50 | Macricostas Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.4M | $6.5M |
| 51 | National Golf Foundation INC | Unclassified | $2.4M | $6.2M |
| 52 | Mortimer J and Eugenie Alter Propp Fund | Philanthropy, Voluntarism & Grantmaking | $2.2M | $2.4M |
| 53 | Coming Home Foundation | Public & Societal Benefit | $2.1M | $123K |
| 54 | Sloan Family Foundation | Philanthropy, Voluntarism & Grantmaking | $2.0M | $2.4M |
| 55 | West Jupiter Community Group INC | Education | $2.0M | $4.2M |
| 56 | Loxahatchee River Historical Society INC | Unclassified | $1.9M | $1.2M |
| 57 | Anngar Foundation | Religion-Related | $1.9M | $11.3M |
| 58 | Bohler Family Infinity Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.9M | $3.9M |
| 59 | El Sol Jupiters Neighborhood Resource Center INC | Human Services | $1.8M | $2.0M |
| 60 | Lankler Family Foundation INC | Human Services | $1.8M | $2.6M |
| 61 | Roger and Myrna Landay Foundation Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $1.7M | $2.9M |
| 62 | Blair Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.7M | $10.8M |
| 63 | John Erbey Foundaton | Philanthropy, Voluntarism & Grantmaking | $1.7M | $2.4M |
| 64 | Boynton Beach Firefighters Retirement Insurance Fund | Mutual & Membership Benefit | $1.5M | $5.6M |
| 65 | Blank Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.5M | $1.9M |
| 66 | Creative Defense Foundation | International, Foreign Affairs & National Security | $1.5M | $626K |
| 67 | McDavid Group Charities INC | Philanthropy, Voluntarism & Grantmaking | $1.5M | $1.1M |
| 68 | St. Vincent de Paul Salvage Store of West Palm Beach INC | Human Services | $1.5M | $631K |
| 69 | James Hawkins Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.4M | $607K |
| 70 | Pipers Angels Foundation INC | Medical Research | $1.4M | $397K |
| 71 | Nacchio Foundation INC | Philanthropy, Voluntarism & Grantmaking | $1.4M | $441K |
| 72 | The John J and Lillian M Taylor Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $2.8M |
| 73 | My Clinic INC | Health Care | $1.1M | $3.5M |
| 74 | Littleton Academy INC | Education | $1.1M | $4.3M |
| 75 | Andrew Red Harris Foundation INC | Education | $1.0M | $387K |
| 76 | Lerman Family Foundation INC | Crime & Legal-Related | $1.0M | $505K |
| 77 | Charles Lafitte Foundation | Philanthropy, Voluntarism & Grantmaking | $977K | $36.0M |
| 78 | Unlimbited Foundation INC | Health Care | $944K | $80K |
| 79 | Thelma B Pittman Jupiter Pre-school INC | Unclassified | $872K | $828K |
| 80 | Guatemalan Tomorrow Fund INC | International, Foreign Affairs & National Security | $851K | $808K |
| 81 | Koginka Sewaluna Foundation INC | Unclassified | $830K | $7.0M |
| 82 | Richard and Clare Lesser Family Foundation | Philanthropy, Voluntarism & Grantmaking | $822K | $946K |
| 83 | Joan and Chester Luby Charitable Trust | Philanthropy, Voluntarism & Grantmaking | $812K | $1.0M |
| 84 | Phyllis & Sidney Reisman Foundation | Philanthropy, Voluntarism & Grantmaking | $787K | $4.3M |
| 85 | The@rick & Alli Gulliver Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $785K | $1.8M |
| 86 | Jupiter Police Foundation INC | Education | $767K | $1.1M |
| 87 | Britta & Denis J Nayden Charitable Foundation Ltd | Philanthropy, Voluntarism & Grantmaking | $754K | $4.7M |
| 88 | Katherine Harding Wunder Foundation | Philanthropy, Voluntarism & Grantmaking | $717K | $1.5M |
| 89 | Deitchman Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $716K | $4.4M |
| 90 | Heichemer Fam Foundation INC | Philanthropy, Voluntarism & Grantmaking | $684K | $4.8M |
| 91 | Dciia Retirement Research Center | Science & Technology | $659K | $28K |
| 92 | Rasmussen Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $654K | $1.2M |
| 93 | Damman Family Foundation Tr | Philanthropy, Voluntarism & Grantmaking | $647K | $2.0M |
| 94 | Ann K & Doug S Brown Family Foundation | Philanthropy, Voluntarism & Grantmaking | $586K | $3.0M |
| 95 | Littleton Acorn Center INC | Arts, Culture & Humanities | $579K | $210K |
| 96 | Pet Cottage INC | Animal-Related | $577K | $419K |
| 97 | Last Reformation INC | Religion-Related | $564K | $186K |
| 98 | The Alan and Jill Miller Foundation | Philanthropy, Voluntarism & Grantmaking | $556K | $14.3M |
| 99 | Jupiter Inlet Beach Club INC | Unclassified | $549K | $1.4M |
| 100 | Autism Project of Palm Beach County INC | Human Services | $531K | $3.4M |