| 1 | Baycare Health Systems INC | Health Care | $4.4B | $16.0B |
| 2 | Morton Plant Hospital Association INC | Health Care | $1.1B | $1.6B |
| 3 | Ncf Charitable Trust | Religion-Related | $479.9M | $1.8B |
| 4 | Camelot Community Care INC | Human Services | $228.4M | $61.8M |
| 5 | Eckerd Youth Alternatives INC | Human Services | $217.9M | $109.7M |
| 6 | Baycare Select Health Plans INC | Health Care | $161.6M | $59.9M |
| 7 | International Generosity Foundation Trust | Religion-Related | $133.2M | $135.8M |
| 8 | Morton Plant Mease Health Services INC | Health Care | $79.6M | $89.3M |
| 9 | Community Health Center of Pinellas INC | Health Care | $75.3M | $68.1M |
| 10 | Early Learning Coalition of Pinnellas County INC | Human Services | $74.9M | $7.7M |
| 11 | Gulf Coast Jewish Family and Community Services INC | Unclassified | $56.5M | $18.6M |
| 12 | Morton Plant Mease Health Care INC | Health Care | $45.2M | $1.3B |
| 13 | Plato Academy Schools Corporation | Education | $43.1M | $98.1M |
| 14 | Habitat for Humanity of Pinellas | Unclassified | $40.2M | $47.3M |
| 15 | Morton Plant Mease Health Care Foundation INC | Health Care | $39.7M | $122.7M |
| 16 | Young Mens Christian Association of the Suncoast INC | Human Services | $37.4M | $48.8M |
| 17 | Ruth Eckerd Hall INC | Arts, Culture & Humanities | $35.4M | $61.6M |
| 18 | Pinellas Community Foundation | Philanthropy, Voluntarism & Grantmaking | $34.8M | $154.6M |
| 19 | William B Snyder Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $25.9M | $24.4M |
| 20 | Clearwater Marine Aquarium INC | Animal-Related | $24.8M | $102.2M |
| 21 | Robert W Duggan Foundation | Philanthropy, Voluntarism & Grantmaking | $24.0M | $91.1M |
| 22 | Directions for Mental Health INC | Unclassified | $21.5M | $13.4M |
| 23 | The Arc Tampa Bay INC | Unclassified | $19.5M | $14.3M |
| 24 | Good Neighbors INC | Food, Agriculture & Nutrition | $17.5M | $385K |
| 25 | Frances Masser Md Charitable Tr | Philanthropy, Voluntarism & Grantmaking | $16.8M | $7.2M |
| 26 | Hope Villages of America INC | Human Services | $15.4M | $5.7M |
| 27 | Saint Pauls School INC | Unclassified | $13.7M | $23.3M |
| 28 | Pinellas Suncoast Association of Realtors INC | Community Improvement & Capacity Building | $12.6M | $44.6M |
| 29 | Hemophilia Alliance Group Purchasing Organization INC | Diseases, Disorders & Medical Disciplines | $10.9M | $26.0M |
| 30 | Athenian Academy INC | Education | $10.4M | $9.0M |
| 31 | Homeless Emergency Project INC | Housing & Shelter | $10.1M | $26.0M |
| 32 | Clearwater Free Clinic INC | Health Care | $9.5M | $12.1M |
| 33 | Pinellas Public Library Cooperative INC | Community Improvement & Capacity Building | $9.4M | $3.5M |
| 34 | Neighborly Care Network INC | Human Services | $9.2M | $5.6M |
| 35 | 211 Tampa Bay Cares INC | Community Improvement & Capacity Building | $8.9M | $3.0M |
| 36 | Galaxy Education INC | Education | $8.7M | $17.9M |
| 37 | Givers Legacy Foundation INC | Philanthropy, Voluntarism & Grantmaking | $8.3M | $68.8M |
| 38 | Community Health Centers of Pinellas Foundation INC | Health Care | $7.7M | $16.5M |
| 39 | Contemporary Housing Alternatives of Florida INC | Housing & Shelter | $7.5M | $42.7M |
| 40 | The Arc Tampa Bay Foundation INC | Human Services | $7.3M | $25.4M |
| 41 | Behavioral Health Management Services INC | Mental Health & Crisis Intervention | $7.3M | $3.3M |
| 42 | Humane Society of Pinellas INC | Animal-Related | $6.6M | $21.7M |
| 43 | Learning Independence for Tomorrow Incorporated | Education | $6.2M | $19.3M |
| 44 | Dwayne Hawkins Family Foundation INC | Philanthropy, Voluntarism & Grantmaking | $5.5M | $14.7M |
| 45 | Chi Chi Rodriguez Youth Foundation | Unclassified | $5.3M | $17.3M |
| 46 | Guardian Trust Foundation INC | Human Services | $5.0M | $82K |
| 47 | Barrett Family Foundation Tr | Education | $5.0M | $6.4M |
| 48 | Turquoise Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $4.8M | $116.6M |
| 49 | True School INC | Education | $4.7M | $3.7M |
| 50 | Collection on Palmetto Foundation INC | Arts, Culture & Humanities | $4.6M | $4.8M |
| 51 | Clearwater Academy International INC | Unclassified | $4.6M | $4.9M |
| 52 | Woodlawn Community Academy INC | Education | $4.3M | $1.1M |
| 53 | Jolley Trolley Transportation of Clearwater INC | Public & Societal Benefit | $4.1M | $4.9M |
| 54 | Better Business Bureau of West Florida INC | Unclassified | $4.0M | $11.7M |
| 55 | Library and Information Resources Network INC | Education | $3.9M | $2.9M |
| 56 | Clearwater Yacht Club | Unclassified | $3.8M | $4.7M |
| 57 | Family Network on Disabilities of Florida INC | Unclassified | $3.7M | $24.7M |
| 58 | Pinellas Education Organization INC | Education | $3.6M | $6.6M |
| 59 | Pinellas Ex Offender Re Entry Coalition INC | Crime & Legal-Related | $3.5M | $4.2M |
| 60 | Manufacturing Technology Deployment Group | Science & Technology | $3.3M | $65K |
| 61 | The Depaul School for Dyslexia INC | Unclassified | $3.1M | $2.6M |
| 62 | Clearwater Neighborhood Housing Services INC | Human Services | $3.0M | $3.8M |
| 63 | Community Service Foundation | Unclassified | $3.0M | $9.2M |
| 64 | National Christian Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.9M | $13.6M |
| 65 | Clothes to Kids INC | Human Services | $2.8M | $3.8M |
| 66 | Sylvan Oaks Foundation INC | Education | $2.7M | $8.1M |
| 67 | Northstar Family Foundation INC | Arts, Culture & Humanities | $2.6M | $180K |
| 68 | Chargers Soccer Club INC | Recreation & Sports | $2.6M | $1.8M |
| 69 | Kimberly Home INC | Unclassified | $2.6M | $3.4M |
| 70 | Lakeside Christian School INC | Education | $2.6M | $662K |
| 71 | Autism Inspired INC | Youth Development | $2.5M | $6.1M |
| 72 | State Chartered Credit Unions in Florida | Unclassified | $2.5M | $40.1M |
| 73 | Clearwater for Youth INC | Youth Development | $2.5M | $5.4M |
| 74 | Community Dental Clinic INC | Health Care | $2.3M | $5.1M |
| 75 | Advocare Trust INC | Unclassified | $2.3M | $7.7M |
| 76 | Washburn Academy INC | Education | $2.3M | $2.4M |
| 77 | Our Lady of Divine Providence House of Prayer Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.2M | $12.1M |
| 78 | Coptic Orthodox Charities INC | Crime & Legal-Related | $2.2M | $566K |
| 79 | Tampa Bay Community Development Corporation | Housing & Shelter | $2.0M | $2.6M |
| 80 | National Christian Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $2.0M | $2.9M |
| 81 | Charity Works INC | Community Improvement & Capacity Building | $1.9M | $741K |
| 82 | Sunshine State Economic Development Corp. | Unclassified | $1.8M | $6.3M |
| 83 | Man Up and Go | Human Services | $1.8M | $789K |
| 84 | Take Action Global INC | Human Services | $1.8M | $656K |
| 85 | Intercultural Advocacy Institute | Crime & Legal-Related | $1.8M | $600K |
| 86 | Howard & Ethel Ross Tr Ua 2 | Philanthropy, Voluntarism & Grantmaking | $1.6M | $4.7M |
| 87 | Suncoast Health Council INC | Unclassified | $1.6M | $715K |
| 88 | Arthritis Research Institute of America INC | Medical Research | $1.5M | $2.7M |
| 89 | Homes for Independence INC | Housing & Shelter | $1.5M | $7.9M |
| 90 | Preserve Vision Florida INC | Unclassified | $1.5M | $646K |
| 91 | High Point Community Pride Association | Community Improvement & Capacity Building | $1.5M | $1.2M |
| 92 | National Safe Boating Council INC | Unclassified | $1.5M | $936K |
| 93 | Mace Kingsley Family Center International | Religion-Related | $1.4M | $1.0M |
| 94 | Brightest Employment Services INC | Employment | $1.4M | $168K |
| 95 | Greater Clearwater Chamber of Commerce | Unclassified | $1.4M | $2.1M |
| 96 | Habitat for Humanity International INC | Housing & Shelter | $1.3M | $1.3M |
| 97 | Skyway Bridge Run | Public & Societal Benefit | $1.3M | $585K |
| 98 | Heart of a Lion Foundation INC | Public & Societal Benefit | $1.3M | $40K |
| 99 | Clearwater Youth Travel Hockey INC | Youth Development | $1.3M | $352K |
| 100 | Bralyn Foundation INC | Unclassified | $1.3M | $6.9M |