| 1 | Bayhealth Medical Center INC | Health Care | $1.3B | $1.8B |
| 2 | Delaware State University | Education | $270.5M | $529.9M |
| 3 | Food for Education Foundation INC | Food, Agriculture & Nutrition | $74.9M | $93.5M |
| 4 | Sustainable Energy Utility INC | Environment | $48.7M | $162.6M |
| 5 | Climate Arc INC | Environment | $44.4M | $30.5M |
| 6 | Delaware State University Foundation INC | Education | $18.5M | $37.5M |
| 7 | Fondo Centroamericano de Mujeres Foundation | Civil Rights, Social Action & Advocacy | $16.9M | $16.9M |
| 8 | Modern Maturity Center INC | Human Services | $12.3M | $16.8M |
| 9 | Neighborgood Partners INC | Food, Agriculture & Nutrition | $10.8M | $47.1M |
| 10 | Delaware Technical & Community College Educational Foundation 866 | Education | $9.4M | $39.8M |
| 11 | Society for the Protection of Underground Networks | Science & Technology | $9.2M | $7.9M |
| 12 | Commandeire D Amerique de la | Recreation & Sports | $8.5M | $6.0M |
| 13 | Early College High School at Delaware State University INC | Education | $8.4M | $9.3M |
| 14 | Academy of Dover Charter School | Education | $8.3M | $15.8M |
| 15 | Boy Scouts of America | Unclassified | $8.3M | $20.2M |
| 16 | Delaware Standardbred Owners Association INC | Unclassified | $8.1M | $13.3M |
| 17 | The Valour Foundation | Philanthropy, Voluntarism & Grantmaking | $8.1M | $14.9M |
| 18 | Mlcommons Association | Community Improvement & Capacity Building | $7.8M | $6.5M |
| 19 | Sewell C Biggs Trust 12-29-89 | Arts, Culture & Humanities | $7.4M | $20.5M |
| 20 | Charter School INC | Education | $7.0M | $13.1M |
| 21 | Delaware Association of Conservation Districts | Environment | $6.6M | $249K |
| 22 | Mid Atlantic Clean Hydrogen Hub INC | Science & Technology | $5.5M | $3.7M |
| 23 | Downtown Dover Partnership Corp. | Unclassified | $5.5M | $9.4M |
| 24 | International Foundation for Valuing Impacts INC | Social Science | $5.1M | $1.6M |
| 25 | Jobs for Delaware Graduates INC | Employment | $4.9M | $5.7M |
| 26 | Robbins Hose Company No 1 | Public Safety, Disaster Preparedness & Relief | $4.6M | $15.0M |
| 27 | Dory Foundation | Philanthropy, Voluntarism & Grantmaking | $4.0M | $1.9M |
| 28 | Village of Hope America INC | Health Care | $4.0M | $1.5M |
| 29 | Friends of Hagal Sheli INC | Philanthropy, Voluntarism & Grantmaking | $3.3M | $3.9M |
| 30 | Pets for Vets INC | Public & Societal Benefit | $3.3M | $5.9M |
| 31 | Palmer Home INC | Unclassified | $3.3M | $5.9M |
| 32 | Progress Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $3.2M | $953 |
| 33 | Palisade Research INC | Science & Technology | $3.2M | $2.4M |
| 34 | Central Delaware Hfh | Housing & Shelter | $3.1M | $10.3M |
| 35 | Childrens Hospital Neonatal Consortium INC | Medical Research | $3.1M | $3.8M |
| 36 | Lutheran Senior Services of Dover INC | Human Services | $2.9M | $4.2M |
| 37 | Stored in My Heart | Religion-Related | $2.8M | $711K |
| 38 | Responsible Innovation Labs INC | Science & Technology | $2.5M | $1.6M |
| 39 | Family Empowerment Media INC | International, Foreign Affairs & National Security | $2.5M | $2.2M |
| 40 | Delaware Healthcare Association | Unclassified | $2.4M | $3.7M |
| 41 | The Childrens Advocacy Center of Delaware INC | Human Services | $2.4M | $3.5M |
| 42 | Delaware Restaurant Association | Unclassified | $2.0M | $2.3M |
| 43 | American College of Bankruptcy | Education | $1.9M | $1.6M |
| 44 | International Medical Aid Foundation | Health Care | $1.9M | $1K |
| 45 | United Aid and Logistics Foundation | International, Foreign Affairs & National Security | $1.8M | $398K |
| 46 | Communities in Schools of Delaware INC | Education | $1.8M | $271K |
| 47 | Delaware State Parents Association | Human Services | $1.8M | $509K |
| 48 | Oh Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.7M | $6.5M |
| 49 | Delaware Bankers Association | Unclassified | $1.6M | $1.7M |
| 50 | Motwani Jadeja Global Foundation | Philanthropy, Voluntarism & Grantmaking | $1.6M | $672K |
| 51 | Sage Future INC | Education | $1.5M | $808K |
| 52 | American Academy of Sciences and Letters INC | Education | $1.5M | $185K |
| 53 | Silver Linings Holding Corporation INC | Community Improvement & Capacity Building | $1.5M | $8.1M |
| 54 | Cepa Foundation INC | International, Foreign Affairs & National Security | $1.5M | $578K |
| 55 | Synchronicity Earth USA INC | Environment | $1.4M | $1.2M |
| 56 | The Naturex Foundation INC | Community Improvement & Capacity Building | $1.4M | $49K |
| 57 | Seed to Growth Foundation | Philanthropy, Voluntarism & Grantmaking | $1.4M | $1.8M |
| 58 | Delaware Association of Realtors | Unclassified | $1.3M | $2.3M |
| 59 | Inurere Foundation | Education | $1.3M | $1.3M |
| 60 | Work-based Learning Alliance INC | Education | $1.3M | $1.6M |
| 61 | American College of Bankruptcy Foundation | Education | $1.3M | $3.1M |
| 62 | Green Beret Project | Human Services | $1.2M | $1.2M |
| 63 | Malengo INC | Education | $1.1M | $38K |
| 64 | Audi Car Club of North America | Public Safety, Disaster Preparedness & Relief | $1.1M | $834K |
| 65 | International Insolvency Institute | Community Improvement & Capacity Building | $1.1M | $1.9M |
| 66 | Humanite INC | International, Foreign Affairs & National Security | $1.1M | $707K |
| 67 | Anchored Hope Biblical Counseling | Mental Health & Crisis Intervention | $1.1M | $50K |
| 68 | Gastro Girl Patient Institute | Health Care | $1.1M | $755K |
| 69 | Africa Mingrid Developers Association INC | Public & Societal Benefit | $1.0M | $490K |
| 70 | Delaware First Media Corporation | Arts, Culture & Humanities | $1.0M | $281K |
| 71 | American Legion | Public & Societal Benefit | $1.0M | $137K |
| 72 | Delaware Rental Preservation Corporation | Housing & Shelter | $1.0M | $5.7M |
| 73 | International Womens Insolvency & Restructuring Confederation INC | Community Improvement & Capacity Building | $957K | $1.2M |
| 74 | Akda Family Foundation | Philanthropy, Voluntarism & Grantmaking | $925K | $831K |
| 75 | Help Initiative INC | Housing & Shelter | $850K | $347K |
| 76 | Global Fund for Assistance INC | Philanthropy, Voluntarism & Grantmaking | $830K | $0 |
| 77 | Liber-net INC | Civil Rights, Social Action & Advocacy | $815K | $387K |
| 78 | Benevolent & Protective Order of Elks of the USA | Unclassified | $797K | $2.1M |
| 79 | Luther Towers of Dover INC | Housing & Shelter | $790K | $1.4M |
| 80 | Central Delaware Christian Academy INC | Unclassified | $777K | $652K |
| 81 | Dover Interfaith Mission for Housing INC | Housing & Shelter | $774K | $5.6M |
| 82 | Delaware Restaurant Association Educational Foundation | Food, Agriculture & Nutrition | $769K | $395K |
| 83 | World Transformation Movement INC | Arts, Culture & Humanities | $766K | $167K |
| 84 | Luther Village I of Dover INC | Housing & Shelter | $760K | $4.9M |
| 85 | Central Delaware Chamber of Commerce INC | Unclassified | $743K | $504K |
| 86 | Delaware Agricultural Museum Association | Unclassified | $714K | $6.1M |
| 87 | Health and Welfare Benefits Trust for Mafmc Employees and Retirees | Mutual & Membership Benefit | $691K | $3.1M |
| 88 | Delaware Financial Education Allian | Public & Societal Benefit | $685K | $959K |
| 89 | Delaware Volunteer Firefighters Association | Public Safety, Disaster Preparedness & Relief | $674K | $874K |
| 90 | India Philanthropy Alliance Association | Philanthropy, Voluntarism & Grantmaking | $674K | $407K |
| 91 | Luther Towers III of Dover INC | Human Services | $673K | $1.3M |
| 92 | Bayhealth Foundation | Health Care | $658K | $14.2M |
| 93 | Twilley Family Foundation | Philanthropy, Voluntarism & Grantmaking | $641K | $110K |
| 94 | Serenity Place INC | Mental Health & Crisis Intervention | $637K | $867K |
| 95 | Delaware Center for Distance Adult Learning INC | Education | $628K | $12K |
| 96 | Correctional Officers Association of Delaware | Employment | $628K | $1.2M |
| 97 | Cendel Foundation | Community Improvement & Capacity Building | $608K | $3.9M |
| 98 | Random Acts INC | Arts, Culture & Humanities | $604K | $839K |
| 99 | The Alora Charitable Foundation | Philanthropy, Voluntarism & Grantmaking | $597K | $18.0M |
| 100 | Delaware Association for Adult Community Education Daace | Education | $595K | $363K |