| 1 | San Antonio Regional Hospital | Health Care | $561.6M | $811.4M |
| 2 | San Antonio Community Hospital Health Care Service Plan | Unclassified | $20.6M | $1.6M |
| 3 | Inland Valley Drug and Alcohol Recovery Services | Mental Health & Crisis Intervention | $15.3M | $12.3M |
| 4 | San Antonio Hospital Foundation INC | Health Care | $14.5M | $62.5M |
| 5 | Augusta Homes | Housing & Shelter | $11.1M | $73.7M |
| 6 | Reach Out West End | Mental Health & Crisis Intervention | $11.0M | $4.1M |
| 7 | Marvin Ronald Berstein Foundation | Religion-Related | $5.9M | $5.7M |
| 8 | There is Hope Incorporated | Human Services | $5.5M | $654K |
| 9 | San Antonio Water Company | Unclassified | $5.4M | $32.3M |
| 10 | Randall W Lewis Family Foundation | Philanthropy, Voluntarism & Grantmaking | $5.1M | $14.9M |
| 11 | West End YMCA | Unclassified | $4.9M | $11.0M |
| 12 | Carden Arbor View School INC | Education | $3.8M | $3.1M |
| 13 | Nasib Foundation | Philanthropy, Voluntarism & Grantmaking | $3.7M | $20.0M |
| 14 | Avector Community Group INC | Education | $2.6M | $2.1M |
| 15 | American Alliance Drug Testing | Unclassified | $2.3M | $2.1M |
| 16 | Empowering Lives International | Religion-Related | $2.3M | $1.6M |
| 17 | Pan de Vida Spanish Ministry of Ontario INC | Unclassified | $2.3M | $1.5M |
| 18 | Youth Mentoring Action Network | Education | $2.0M | $999K |
| 19 | Upland Community Housing INC | Housing & Shelter | $1.7M | $7.6M |
| 20 | Connect Senior Services INC | Housing & Shelter | $1.7M | $6.1M |
| 21 | California Rental Association | Unclassified | $1.7M | $5.0M |
| 22 | Samaritan Counseling Center | Human Services | $1.4M | $2.2M |
| 23 | Childrens Hope Group Home | Human Services | $1.3M | $957K |
| 24 | Leland and Julia Scheu Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.2M | $2.5M |
| 25 | Friends of Upland Animal Shelter INC | Animal-Related | $1.2M | $483K |
| 26 | Warrior for Children | Human Services | $1.2M | $99K |
| 27 | Ontario Community Foundation INC | Unclassified | $1.2M | $3.4M |
| 28 | Socal Mc | Education | $1.2M | $96K |
| 29 | A Lot of Good | Human Services | $1.2M | $360K |
| 30 | Anabi Family Foundation | Philanthropy, Voluntarism & Grantmaking | $1.1M | $1.5M |
| 31 | Assistance League of the Foothill Communities | Community Improvement & Capacity Building | $1.0M | $2.1M |
| 32 | Western States Trucking Association | Unclassified | $961K | $1.2M |
| 33 | Foothill Family Shelter INC | Unclassified | $953K | $3.4M |
| 34 | American Postal Workers Union | Unclassified | $943K | $349K |
| 35 | Hometown Community Development Corporation | Housing & Shelter | $866K | $10.5M |
| 36 | Lmws INC | Unclassified | $711K | $2.4M |
| 37 | Fascia Research Society | Science & Technology | $630K | $619K |
| 38 | Gamblers Anonymous National Service Office | Mental Health & Crisis Intervention | $615K | $717K |
| 39 | Upland-foothill Kiwanis Foundation | Human Services | $545K | $1.3M |
| 40 | Center for Biblical Unity | Religion-Related | $541K | $662K |
| 41 | Upland Chamber of Commerce | Community Improvement & Capacity Building | $497K | $336K |
| 42 | Ovation School for the Performing Arts | Arts, Culture & Humanities | $475K | $48K |
| 43 | Pt Education INC | Education | $471K | $146K |
| 44 | Price Foundation INC | Unclassified | $465K | $1.7M |
| 45 | Uceus Corp. | Youth Development | $451K | $268K |
| 46 | Zion Mountain Foundation 12302009 | Philanthropy, Voluntarism & Grantmaking | $444K | $374K |
| 47 | Augusta Community Center | Housing & Shelter | $390K | $77K |
| 48 | Railway & Locomotive Historical Society INC Southern Ca Chapter | Unclassified | $370K | $1.7M |
| 49 | Glendale Chinese School | Education | $326K | $63K |
| 50 | Upland Police Foundation | Philanthropy, Voluntarism & Grantmaking | $314K | $406K |
| 51 | Kurdish American Education Society | Education | $305K | $608K |
| 52 | West End Consolidated Water Company | Unclassified | $288K | $2.4M |
| 53 | Medical Staff of San Antonio Regional Hospital | Mutual & Membership Benefit | $284K | $236K |
| 54 | Smile Unto Him | Health Care | $273K | $306K |
| 55 | Southwest Music Education Association | Arts, Culture & Humanities | $263K | $193K |
| 56 | Southern Pacific Historical and Technical Society INC | Arts, Culture & Humanities | $242K | $330K |
| 57 | Youth Helpers INC | Religion-Related | $226K | $132K |
| 58 | Friends of the Upland Public Library | Unclassified | $198K | $576K |
| 59 | San Bernardino County Sheriff S Council | Unclassified | $187K | $161K |
| 60 | Little League Baseball INC | Unclassified | $178K | $66K |
| 61 | Scots Athletic Foundation | Recreation & Sports | $178K | $14K |
| 62 | Friends of Upland Choral Music | Education | $176K | $121K |
| 63 | Upland Highland Regiment Boosters INC | Education | $175K | $52K |
| 64 | Little League Baseball INC | Unclassified | $174K | $78K |
| 65 | Helping Out Pets Everyday | Animal-Related | $174K | $48K |
| 66 | Baloojas Foundation INC | Animal-Related | $173K | $72K |
| 67 | For a Reason INC | International, Foreign Affairs & National Security | $172K | $287K |
| 68 | St. Anthony Bridges to Home | Housing & Shelter | $167K | $285K |
| 69 | Chaffey Communities Cultural Center | Arts, Culture & Humanities | $161K | $550K |
| 70 | Viking Wrestling Boosters Club INC | Recreation & Sports | $156K | $11K |
| 71 | Eagles Wings Ministries | Unclassified | $151K | $160K |
| 72 | Upland Travelers Club INC | Unclassified | $141K | $37K |
| 73 | Su Misericordia | Human Services | $140K | $68K |
| 74 | White House Healing Center | Housing & Shelter | $137K | $80K |
| 75 | Kingdom Kidz Foster Family Agency | Health Care | $136K | $41K |
| 76 | Inland Valley Baseball Association | Recreation & Sports | $132K | $4K |
| 77 | Upland Police Officers Association | Unclassified | $131K | $272K |
| 78 | Little League Baseball INC | Unclassified | $130K | $109K |
| 79 | Fdr Foundation | Mental Health & Crisis Intervention | $128K | $29K |
| 80 | Elias Malki Middle East Gospel Outreach | Religion-Related | $127K | $2.3M |
| 81 | Joy in Service Foundation | Human Services | $126K | $263K |
| 82 | California Teachers Association | Unclassified | $124K | $407K |
| 83 | Inland Salt Water Anglers Club | Recreation & Sports | $115K | $23K |
| 84 | Ahlul Beyt Mosque INC | Religion-Related | $105K | $818K |
| 85 | Upland Girls Softball League | Unclassified | $105K | $161K |
| 86 | National Charity League Foothill Chapter INC | Unclassified | $101K | $57K |
| 87 | Samta Foundation | Philanthropy, Voluntarism & Grantmaking | $100K | $182K |
| 88 | Whitefish Foundation | Housing & Shelter | $93K | $419K |
| 89 | Church of Christ Foundation | Unclassified | $89K | $1.1M |
| 90 | Jeremy Giambi Fund | Mental Health & Crisis Intervention | $89K | $74K |
| 91 | Love Them All Foundation | Human Services | $84K | $37K |
| 92 | Forgiving for Living INC | Human Services | $79K | $66K |
| 93 | Southern California Festival and Sale INC | Human Services | $73K | $11K |
| 94 | Rotary Club of Upland Foundation INC | Education | $69K | $74K |
| 95 | Afar Foundation | International, Foreign Affairs & National Security | $67K | $225K |
| 96 | Southern California Athletics INC | Recreation & Sports | $67K | $106K |
| 97 | Ponoma Valley Chinese School | Unclassified | $65K | $235K |
| 98 | Links INC | Unclassified | $64K | $38K |
| 99 | Uplanders Club Charitable Organization | Philanthropy, Voluntarism & Grantmaking | $63K | $16K |
| 100 | PTA California Congress of Parents Teachers & Students INC | Unclassified | $61K | $66K |