| 1 | Honorhealth | Health Care | $3.9B | $4.8B |
| 2 | Vitalant | Health Care | $963.9M | $891.0M |
| 3 | Scottsdale Healthcare Corp. | Health Care | $279.2M | $137.9M |
| 4 | Arizona Dental Insurance Service | Unclassified | $181.4M | $164.3M |
| 5 | Basis Charter Schools INC | Education | $176.3M | $330.6M |
| 6 | Honorhealth Foundation | Health Care | $170.1M | $360.6M |
| 7 | Alliance Defending Freedom | Civil Rights, Social Action & Advocacy | $125.4M | $102.8M |
| 8 | Desert Mountain Club INC | Recreation & Sports | $120.5M | $203.3M |
| 9 | Childhelp INC | Human Services | $71.0M | $34.3M |
| 10 | Simone Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $64.4M | $115.2M |
| 11 | Dorrance Family Foundation | Unclassified | $59.3M | $111.3M |
| 12 | Scottsdale Arts | Arts, Culture & Humanities | $52.7M | $25.7M |
| 13 | Dorrance Foundation for Education | Philanthropy, Voluntarism & Grantmaking | $50.1M | $65.0M |
| 14 | City of Scottsdale Municipal Property Corp. | Unclassified | $49.0M | $407.1M |
| 15 | Arizona Leadership Foundation INC | Education | $48.5M | $16.6M |
| 16 | Diane and Bruce Halle Foundation | Philanthropy, Voluntarism & Grantmaking | $47.7M | $16K |
| 17 | Westminster Village INC | Human Services | $42.1M | $49.0M |
| 18 | Arizona Tuition Connection INC | Education | $33.6M | $70.9M |
| 19 | National Institute for Excellence in Teaching | Education | $33.6M | $53.6M |
| 20 | Worldatwork | Mutual & Membership Benefit | $31.2M | $33.0M |
| 21 | People-people-people Foundation Dated 4-19-2018 | Philanthropy, Voluntarism & Grantmaking | $28.2M | $2.4M |
| 22 | Bob and Renee Parsons Foundation | Philanthropy, Voluntarism & Grantmaking | $28.2M | $24.8M |
| 23 | Fiesta Sports Foundation | Unclassified | $23.8M | $95.2M |
| 24 | Scottsdale Convention and Vistors Bureau INC | Community Improvement & Capacity Building | $22.3M | $17.4M |
| 25 | Arizona Local Government Employee Benefits Trust | Employment | $21.3M | $15.2M |
| 26 | Boys & Girls Clubs of Scottsdale INC | Youth Development | $20.0M | $27.2M |
| 27 | Las Sendas Community Association | Community Improvement & Capacity Building | $17.3M | $17.6M |
| 28 | Fit Kids INC | Education | $16.6M | $31.5M |
| 29 | The Estancia Club INC | Recreation & Sports | $16.4M | $32.3M |
| 30 | Troon Country Club INC | Unclassified | $16.4M | $29.5M |
| 31 | National Council for Prescription Drug Programs INC | Unclassified | $15.4M | $27.4M |
| 32 | Career Success Educational Development | Education | $14.6M | $25.2M |
| 33 | Arizona State University Research Park INC | Education | $14.5M | $79.3M |
| 34 | Goldberg Family Foundation | Philanthropy, Voluntarism & Grantmaking | $14.3M | $14.8M |
| 35 | Jewish Community Foundation of Greater Phoenix | Philanthropy, Voluntarism & Grantmaking | $13.9M | $92.8M |
| 36 | Valley of the Sun Jewish Community Center INC | Unclassified | $13.3M | $11.7M |
| 37 | Vitalant Foundation | Health Care | $13.1M | $38.9M |
| 38 | Frank Lloyd Wright Foundation | Education | $12.5M | $22.1M |
| 39 | Make a Wish Foundation of Arizona INC | Health Care | $12.2M | $13.1M |
| 40 | Dc Ranch Association INC | Housing & Shelter | $12.2M | $15.8M |
| 41 | USA Pickleball Association | Recreation & Sports | $12.1M | $4.2M |
| 42 | Desert Mission INC | Human Services | $11.8M | $8.9M |
| 43 | Cochise Combined Tr | Unclassified | $11.1M | $11.8M |
| 44 | Estrella Joint Committee INC a Non-profit Corporation | Community Improvement & Capacity Building | $11.0M | $7.1M |
| 45 | Pinnacle Peak Country Club INC | Unclassified | $10.6M | $17.7M |
| 46 | Merchants Industry Fund | Unclassified | $10.2M | $1.2M |
| 47 | Stewardship Endowment Fund | Religion-Related | $10.2M | $70.1M |
| 48 | Terravita Country Club INC | Recreation & Sports | $10.1M | $19.2M |
| 49 | Villages at Estrella Mountain Ranch Community Association | Community Improvement & Capacity Building | $9.6M | $6.8M |
| 50 | Jewish Community Association of Greater Phoenix | Philanthropy, Voluntarism & Grantmaking | $9.1M | $35.9M |
| 51 | Robert and Judith Atlas Family Foundation | Philanthropy, Voluntarism & Grantmaking | $9.0M | $9.1M |
| 52 | Fathers Eyes Foundation | Philanthropy, Voluntarism & Grantmaking | $8.9M | $5.5M |
| 53 | Dudley Family Foundation | Philanthropy, Voluntarism & Grantmaking | $8.5M | $26.5M |
| 54 | The Nroc Project | Education | $8.3M | $10.7M |
| 55 | Viridian Residential Association | Community Improvement & Capacity Building | $8.0M | $3.2M |
| 56 | Hopekids INC | Health Care | $8.0M | $4.1M |
| 57 | Power Ranch Community Association | Housing & Shelter | $7.9M | $12.3M |
| 58 | Dc Ranch Community Council | Housing & Shelter | $7.7M | $8.6M |
| 59 | Arizona Musicfest | Arts, Culture & Humanities | $7.6M | $11.3M |
| 60 | Phoenix Seminary INC | Education | $7.6M | $3.1M |
| 61 | International School of Arizona | Education | $7.3M | $11.6M |
| 62 | Real Salt Lake Az | Recreation & Sports | $7.3M | $776K |
| 63 | Globe Foundation | Unclassified | $7.2M | $26.6M |
| 64 | Arizona Private Education Scholarship Fund INC | Education | $7.1M | $7.0M |
| 65 | Barbara Roastingear and Henry Oliver III Family Foundation | Philanthropy, Voluntarism & Grantmaking | $7.1M | $9.9M |
| 66 | Scottsdale Museum of the West INC | Arts, Culture & Humanities | $7.1M | $12.1M |
| 67 | Jack Ingebritson Foundation INC | Philanthropy, Voluntarism & Grantmaking | $7.0M | $10.8M |
| 68 | Arcadia Scottsdale United Soccer Club | Unclassified | $6.8M | $2.6M |
| 69 | Paideia Foundation | Philanthropy, Voluntarism & Grantmaking | $6.8M | $10.9M |
| 70 | Pardes Jewish Day School INC | Education | $6.7M | $9.0M |
| 71 | Johnson Ranch Community Association INC | Housing & Shelter | $6.7M | $8.9M |
| 72 | Jennie H Olson Charitable Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.7M | $7.2M |
| 73 | Chileno Bay Foundation INC | Philanthropy, Voluntarism & Grantmaking | $6.6M | $535K |
| 74 | Terravita Golf Club INC | Recreation & Sports | $6.5M | $15.1M |
| 75 | McCormick Ranch Property Owners Association INC | Unclassified | $6.3M | $3.8M |
| 76 | Council on Chiropractic Education INC | Unclassified | $6.0M | $8.2M |
| 77 | Waste Not INC | Food, Agriculture & Nutrition | $5.9M | $1.3M |
| 78 | Gainey Ranch Community Association | Community Improvement & Capacity Building | $5.9M | $7.9M |
| 79 | Raymond and June Kuns Foundation | Unclassified | $5.8M | $3.0M |
| 80 | Impact Through Golf Foundation Napa Valley | Community Improvement & Capacity Building | $5.7M | $1.0M |
| 81 | Vistancia Village a Community Association | Community Improvement & Capacity Building | $5.7M | $4.2M |
| 82 | Ironwood Crossing Homeowners Association | Community Improvement & Capacity Building | $5.7M | $5.8M |
| 83 | Grayhawk Community Association | Housing & Shelter | $5.4M | $7.9M |
| 84 | Pitre Family Foundation | Philanthropy, Voluntarism & Grantmaking | $5.4M | $48.0M |
| 85 | Arabian Horse Association of Arizona | Unclassified | $5.4M | $5.7M |
| 86 | T W Lewis Foundation | Philanthropy, Voluntarism & Grantmaking | $5.4M | $10.2M |
| 87 | Military Support Foundation | Health Care | $5.4M | $97K |
| 88 | Boy Scouts of America | Unclassified | $5.1M | $23.0M |
| 89 | Desert Ridge Community Association | Human Services | $5.0M | $6.4M |
| 90 | Robert D Fisher Foundation INC | Philanthropy, Voluntarism & Grantmaking | $4.9M | $8.2M |
| 91 | Association for Learning Environments | Unclassified | $4.9M | $1.4M |
| 92 | Valley of the Sun Bowl Foundation | Recreation & Sports | $4.9M | $926K |
| 93 | Boys & Girls Clubs of Greater Scottsdale Foundation | Philanthropy, Voluntarism & Grantmaking | $4.9M | $30.7M |
| 94 | Alcor Life Extension Foundation INC | Science & Technology | $4.7M | $28.4M |
| 95 | Music Serving the Word Ministries | Religion-Related | $4.7M | $26.3M |
| 96 | Chambers Creek Community Association INC | Housing & Shelter | $4.7M | $287K |
| 97 | Opc Foundation | Unclassified | $4.5M | $2.9M |
| 98 | Susan and Ford Schumann Foundation | Unclassified | $4.5M | $4.5M |
| 99 | Not My Kid INC | Human Services | $4.3M | $6.5M |
| 100 | Scottsdale Training and Rehabilitation Services INC | Human Services | $4.2M | $3.9M |