| 1 | Banner Health | Health Care | $11.1B | $17.7B |
| 2 | Mercy Care | Unclassified | $5.1B | $1.3B |
| 3 | Grand Canyon University | Education | $2.0B | $2.1B |
| 4 | Banner University Family Care | Unclassified | $2.0B | $530.4M |
| 5 | Phoenix Childrens Hospital | Health Care | $1.8B | $2.9B |
| 6 | Teamsters Western Region and New Jersey Health Care Fund | Unclassified | $1.7B | $4.3B |
| 7 | Banner Medical Group | Health Care | $619.3M | $174.3M |
| 8 | Banner-university Medical Group | Health Care | $614.5M | $131.3M |
| 9 | Arizona Community Foundation | Philanthropy, Voluntarism & Grantmaking | $401.5M | $1.2B |
| 10 | Goodwill Industries of Central Arizona INC | Unclassified | $350.6M | $411.8M |
| 11 | Oneaz Credit Union | Public & Societal Benefit | $318.4M | $3.4B |
| 12 | Banner-university Care Advantage | Health Care | $305.0M | $87.3M |
| 13 | Wyoming Medical Center INC | Health Care | $286.7M | $258.3M |
| 14 | Sjouwerman Foundation INC | Philanthropy, Voluntarism & Grantmaking | $270.5M | $160.3M |
| 15 | District Medical Group INC | Health Care | $270.1M | $117.3M |
| 16 | St. Marys Food Bank Alliance | Food, Agriculture & Nutrition | $260.9M | $75.4M |
| 17 | Arizona Financial Credit Union | Public & Societal Benefit | $226.0M | $3.4B |
| 18 | Hospice of the Valley | Human Services | $219.6M | $209.1M |
| 19 | Hospice Endowment Trust Fund of Phoenix Arizona | Unclassified | $218.5M | $816.1M |
| 20 | Helios Education Foundation | Public & Societal Benefit | $216.3M | $879.7M |
| 21 | Chicanos Por la Causa INC | Human Services | $195.7M | $1.3B |
| 22 | Prepass Safety Alliance | Science & Technology | $193.2M | $501.4M |
| 23 | Food for the Hungry INC | International, Foreign Affairs & National Security | $180.4M | $37.8M |
| 24 | Southwest Multi-craft Health & Welfare Trust Fund | Unclassified | $177.8M | $143.5M |
| 25 | Make- A- Wish Foundation of America | Unclassified | $158.1M | $116.7M |
| 26 | Barrow Neurological Foundation | Diseases, Disorders & Medical Disciplines | $156.9M | $264.2M |
| 27 | United Food & Commercial Workers & Emps Arizona Health & Welfare Tr | Unclassified | $154.9M | $178.7M |
| 28 | Fh Association | Philanthropy, Voluntarism & Grantmaking | $153.2M | $21.5M |
| 29 | Mountain Park Health Center | Health Care | $151.7M | $136.6M |
| 30 | Utah-idaho Teamsters Security Fund | Unclassified | $148.9M | $73.4M |
| 31 | Virginia G Piper Charitable Trust 08-11-95 | Philanthropy, Voluntarism & Grantmaking | $144.2M | $429.9M |
| 32 | Valley of the Sun United Way | Philanthropy, Voluntarism & Grantmaking | $133.5M | $101.7M |
| 33 | Banner Medical Group Colorado | Health Care | $123.9M | $22.8M |
| 34 | The Thunderbirds | Unclassified | $123.3M | $77.7M |
| 35 | Flinn Foundation | Education | $121.6M | $263.1M |
| 36 | Adelante Healthcare INC | Health Care | $120.6M | $87.1M |
| 37 | St. Josephs Foundation | Human Services | $114.7M | $116.1M |
| 38 | Southwest Behavioral Health Services INC | Mental Health & Crisis Intervention | $103.1M | $84.9M |
| 39 | Diocesan Council for the Society of St. Vincent de Paul Diocese Phoenix | Religion-Related | $99.5M | $126.8M |
| 40 | Translational Genomics Research Institute | Medical Research | $98.8M | $148.6M |
| 41 | Terros INC | Unclassified | $98.8M | $64.6M |
| 42 | Southwest Human Development | Unclassified | $96.4M | $68.8M |
| 43 | Arizona Food Bank Network | Food, Agriculture & Nutrition | $93.0M | $9.1M |
| 44 | Marine Preservation Association | Unclassified | $92.5M | $52.8M |
| 45 | Petsmart Charities INC | Animal-Related | $76.3M | $90.3M |
| 46 | United Food & Commercial Workers Union 711 Food Emplyrs Bene Fund | Unclassified | $70.4M | $84.2M |
| 47 | Arizona Humane Society | Animal-Related | $68.5M | $128.0M |
| 48 | Arizona Operating Engineers Health and Welfare Trust Fund | Unclassified | $68.1M | $62.6M |
| 49 | Arizona Behavioral Health Corporation | Unclassified | $65.8M | $24.2M |
| 50 | Kemper & Ethel Marley Foundation | Philanthropy, Voluntarism & Grantmaking | $64.9M | $250.1M |
| 51 | Neighborhood Outreach Access to Health | Health Care | $64.8M | $61.5M |
| 52 | Moreno Family Foundation | Philanthropy, Voluntarism & Grantmaking | $61.8M | $143.1M |
| 53 | Ability360 INC | Human Services | $61.3M | $89.0M |
| 54 | Lincoln Institute of Land Policy | Education | $59.5M | $774.4M |
| 55 | Valley of the Sun Young Mens Christian Association | Human Services | $55.1M | $51.5M |
| 56 | Barry Goldwater Institute for Public Policy Research | Public & Societal Benefit | $54.3M | $44.2M |
| 57 | Central Texas Health and Benefit Trust Fund | Mutual & Membership Benefit | $54.2M | $39.0M |
| 58 | Kaizen Educational Foundation | Arts, Culture & Humanities | $53.9M | $67.4M |
| 59 | Phoenix Childrens Hospital Foundation | Health Care | $52.8M | $155.8M |
| 60 | American Charter Schools Foundation | Education | $51.8M | $95.3M |
| 61 | Arizona Central Credit Union | Unclassified | $50.4M | $688.9M |
| 62 | Arizona Autism United INC | Human Services | $50.2M | $23.2M |
| 63 | Arizona Center for Nature Conservation | Animal-Related | $49.9M | $111.2M |
| 64 | Catholic Charities Community Services INC | Human Services | $49.0M | $31.0M |
| 65 | Jewish Family and Childrens Service INC | Human Services | $45.3M | $34.7M |
| 66 | Greathearts Arizona | Education | $44.4M | $255.2M |
| 67 | Musical Instrument Museum | Arts, Culture & Humanities | $44.0M | $199.6M |
| 68 | Area Agency on Aging Region One Incorporated | Human Services | $43.6M | $23.6M |
| 69 | United Association of Journeymen & Apprentices of the Plumbing & Pipe | Unclassified | $43.5M | $51.1M |
| 70 | Arizona Association of Community Health Centers INC | Health Care | $42.7M | $32.3M |
| 71 | Vitalyst Health Foundation | Health Care | $41.9M | $144.0M |
| 72 | Boys & Girls Clubs of the Valley INC | Unclassified | $41.1M | $66.7M |
| 73 | Lifewell | Unclassified | $40.6M | $42.6M |
| 74 | Banner Health Foundation | Health Care | $40.0M | $186.9M |
| 75 | Native American Connections INC | Mental Health & Crisis Intervention | $39.7M | $100.9M |
| 76 | Phoenix Gospel Mission | Religion-Related | $39.4M | $50.3M |
| 77 | Copper State Credit Union | Unclassified | $38.1M | $592.1M |
| 78 | Beatitudes Campus of Care | Human Services | $37.5M | $108.6M |
| 79 | Crossroads INC | Mental Health & Crisis Intervention | $37.3M | $66.5M |
| 80 | Arizona Autism Charter Schools INC | Education | $36.2M | $52.2M |
| 81 | Creighton University Arizona Health Education Alliance | Health Care | $34.4M | $10.1M |
| 82 | Umom New Day Centers INC | Housing & Shelter | $33.2M | $43.6M |
| 83 | Girl Scouts-arizona Cactus Pine Council INC | Youth Development | $33.1M | $40.7M |
| 84 | Maricopa Association of Governments | Unclassified | $32.6M | $39.2M |
| 85 | Circle the City | Human Services | $31.8M | $18.2M |
| 86 | The 3000 Club | Human Services | $31.6M | $176K |
| 87 | Arizona Sheet Metal Trade Trust Fund | Unclassified | $31.6M | $34.2M |
| 88 | Southwest Network | Health Care | $31.4M | $20.9M |
| 89 | Native Health | Unclassified | $30.2M | $42.0M |
| 90 | International Association of Machinists & Aerospace Workers | Unclassified | $28.9M | $14.0M |
| 91 | Desert Botanical Garden | Environment | $28.8M | $81.9M |
| 92 | Plumbers and Pipefitters Local Union No 286 Health and Welfare Fu | Unclassified | $28.5M | $28.8M |
| 93 | Arizona Community Action Association INC | Unclassified | $28.4M | $26.4M |
| 94 | Rodel Foundation | Philanthropy, Voluntarism & Grantmaking | $28.2M | $64.1M |
| 95 | Health Current | Health Care | $28.1M | $3.3M |
| 96 | Inter-tribal Council of Arizona INC | Unclassified | $27.8M | $13.3M |
| 97 | Lutheran Social Services of the Southwest | Religion-Related | $27.5M | $8.5M |
| 98 | Human Services Campus INC | Housing & Shelter | $25.9M | $34.4M |
| 99 | Raza Development Fund INC | Community Improvement & Capacity Building | $25.7M | $363.1M |
| 100 | Southwest Autism Research and Resource Center | Medical Research | $25.4M | $38.0M |