| 1 | Sanford Sioux Falls | $6.1B | $6.1B | $4.3B |
| 2 | East River Electric Power Cooperative INC Madison | $371.4M | $371.4M | $1.0B |
| 3 | Delta Dental of South Dakota Pierre | $114.3M | $110.7M | $45.1M |
| 4 | Sioux Valley-southwestern Electric Cooperative INC Colman | $109.1M | $108.1M | $384.7M |
| 5 | Rushmore Electric Power Cooperative INC Rapid City | $84.8M | $11.0M | $79.2M |
| 6 | Presbyterian Retirement Village of Rapid City INC Rapid City | $80.7M | $31.1M | $158.7M |
| 7 | Rural Health Care INC Ft Pierre | $65.9M | $65.9M | $29.6M |
| 8 | West River Electric Association INC Wall | $49.8M | $49.0M | $179.3M |
| 9 | Childrens Care Hospital & School Sioux Falls | $46.6M | $46.6M | $43.1M |
| 10 | Pine Rock Foundation INC Sioux Falls | $45.4M | $0 | $98.1M |
| 11 | Association of Hutterian Brethren Churches INC Aberdeen | $33.6M | $33.6M | $30.5M |
| 12 | Northern Electric Cooperative Incorporated Bath | $31.5M | $31.4M | $117.4M |
| 13 | Oahe Electric Cooperative INC Blunt | $30.1M | $30.0M | $42.8M |
| 14 | Dakota Energy Cooperative INC Huron | $29.5M | $28.3M | $65.0M |
| 15 | Mid-dakota Rural Water System INC Miller | $27.9M | $27.9M | $146.3M |
| 16 | Lutheran Social Services of South Dakota Sioux Falls | $27.2M | $27.2M | $19.9M |
| 17 | Black Hills Electric Cooperative INC Custer | $25.9M | $25.8M | $82.4M |
| 18 | Kingbrook Rural Water System INC Arlington | $24.9M | $24.9M | $86.2M |
| 19 | Lake Region Electric Association INC Webster | $21.9M | $21.2M | $53.7M |
| 20 | Web Water Development Assoc INC Aberdeen | $20.2M | $20.2M | $239.4M |
| 21 | Butte Electric Cooperative INC Newell | $18.7M | $10.5M | $71.8M |
| 22 | Fem Electric Association INC Ipswich | $18.7M | $18.2M | $49.4M |
| 23 | West Central Electric Cooperative Incorporated Murdo | $18.6M | $18.5M | $57.3M |
| 24 | Behavior Management Systems INC Rapid City | $18.2M | $16.4M | $12.0M |
| 25 | Northern State University Foundation Aberdeen | $17.5M | $13.5M | $70.8M |
| 26 | Lacreek Electric Association INC Martin | $17.0M | $16.9M | $68.2M |
| 27 | Codington-clark Electric Cooperative INC Watertown | $16.7M | $16.4M | $61.7M |
| 28 | Cherry-todd Electric Cooperative INC Mission | $16.6M | $16.6M | $55.6M |
| 29 | H-d Electric Cooperative INC Clear Lake | $16.4M | $15.3M | $50.3M |
| 30 | Sioux Falls Development Foundation INC Sioux Falls | $16.3M | $9.3M | $106.5M |
| 31 | Rural Office of Community Services Wagner | $15.9M | $15.9M | $4.3M |
| 32 | Youth & Family Services INC Rapid City | $15.5M | $15.4M | $18.9M |
| 33 | Evah C Cray Residuary Charitable Tr Sioux Falls | $15.3M | $0 | $8.7M |
| 34 | St. Michaels Hospital Tyndall | $15.0M | $15.0M | $25.5M |
| 35 | Grand Electric Cooperative INC Bison | $14.5M | $13.8M | $67.6M |
| 36 | Moreau-grand Electric Cooperative INC Timber Lake | $14.4M | $7.7M | $59.8M |
| 37 | Bethesda Home of Aberdeen INC Aberdeen | $14.1M | $14.1M | $14.4M |
| 38 | Whetstone Valley Electric Cooperative INC Milbank | $14.1M | $12.6M | $44.6M |
| 39 | Bon Homme-yankton Electric Association INC Tabor | $12.9M | $12.4M | $41.3M |
| 40 | Dakota Charitable Foundation INC Rapid City | $12.7M | $0 | $20.3M |
| 41 | Community Health Center of the Black Hills INC Rapid City | $12.4M | $10.6M | $9.8M |
| 42 | Clay-union Electric Corporation Vermillion | $10.9M | $10.6M | $45.2M |
| 43 | Embe Sioux Falls | $10.9M | $10.7M | $8.3M |
| 44 | Minnehaha Country Club Sioux Falls | $10.5M | $8.7M | $16.4M |
| 45 | East Dakota Educational Cooperative Sioux Falls | $9.7M | $9.7M | $4.5M |
| 46 | Rosebud Electric Cooperative INC Gregory | $9.6M | $9.6M | $31.6M |
| 47 | Regency Managed Properties Benefit Trust Sioux Falls | $9.5M | $9.5M | $1.9M |
| 48 | Enemy Swim Day School Waubay | $9.5M | $9.4M | $16.1M |
| 49 | Community Memorial Hospital INC Burke | $9.5M | $9.0M | $17.5M |
| 50 | Our Home INC Huron | $9.4M | $9.4M | $6.1M |