| 1 | Central Electric Power Cooperative INC Columbia | $1.6B | $1.6B | $558.9M |
| 2 | St. Francis Hospital INC Greenville | $889.6M | $850.9M | $586.8M |
| 3 | Berkeley Electric Cooperative INC Moncks Corner | $488.3M | $488.2M | $766.2M |
| 4 | Wofford College Spartanburg | $301.3M | $171.4M | $761.0M |
| 5 | Blue Ridge Electric Cooperative Pickens | $208.0M | $208.0M | $580.1M |
| 6 | Palmetto Electric Cooperative INC Ridgeland | $194.8M | $194.8M | $321.1M |
| 7 | Mid-carolina Electric Cooperative INC Lexington | $157.8M | $157.8M | $403.9M |
| 8 | York Electric Cooperative INC York | $151.2M | $151.2M | $282.1M |
| 9 | Aiken Electric Cooperative INC Aiken | $145.7M | $145.7M | $580.5M |
| 10 | Santee Electric Cooperative INC Kingstree | $135.9M | $135.9M | $282.8M |
| 11 | Sonoco Employees Benefit Trust Hartsville | $121.2M | $121.2M | $304K |
| 12 | Fairfield Electric Cooperative INC Blythewood | $93.5M | $87.9M | $148.5M |
| 13 | Black River Electric Cooperative INC Sumter | $91.4M | $91.4M | $133.2M |
| 14 | Lowcountry Food Bank INC Charleston | $90.2M | $90.1M | $35.1M |
| 15 | Myrtle Beach Area Chamber of Commerce Myrtle Beach | $83.6M | $83.6M | $41.2M |
| 16 | Eau Claire Cooperative Health Center INC Columbia | $76.9M | $76.9M | $33.7M |
| 17 | Lynches River Electric Cooperative INC Pageland | $66.1M | $66.1M | $148.7M |
| 18 | Broad River Electric Cooperative INC Cowpens | $62.3M | $62.3M | $166.7M |
| 19 | Tri-county Electric Cooperative INC St. Matthews | $60.5M | $60.5M | $178.7M |
| 20 | Newberry Electric Cooperative INC Newberry | $53.7M | $53.7M | $112.6M |
| 21 | Abney Foundation Anderson | $38.4M | $0 | $51.3M |
| 22 | Container Royalties Supplemental Charleston | $38.2M | $38.2M | $24.5M |
| 23 | Little River Electric Cooperative INC Abbeville | $34.2M | $34.2M | $80.5M |
| 24 | Coastal Electric Cooperative INC Walterboro | $30.6M | $30.6M | $66.6M |
| 25 | Clc Administrative Services INC Spartanburg | $29.9M | $29.9M | $4.0M |
| 26 | South Carolina Life and Health Insurance Guaranty Association Columbia | $29.8M | $29.8M | $55.4M |
| 27 | Rolling Green Village Greenville | $29.2M | $29.1M | $87.3M |
| 28 | South Carolina Property and Casualty Insurance Guaranty Assoc Columbia | $28.1M | $28.1M | $68.8M |
| 29 | Spartanburg Day School Spartanburg | $26.7M | $14.4M | $72.6M |
| 30 | Cypress Club INC Hilton Head | $25.9M | $25.9M | $36.8M |
| 31 | University of South Carolina Business Partnership Foundation Columbia | $24.5M | $17.3M | $173.2M |
| 32 | Fetter Health Care Network INC Charleston | $23.9M | $23.9M | $14.3M |
| 33 | Tri-development Center of Aiken County Aiken | $22.8M | $22.8M | $14.8M |
| 34 | The Williams Brice Edwards Charitable Trust Sumter | $22.1M | $0 | $57.4M |
| 35 | Greenville Country Club Greenville | $22.0M | $21.9M | $39.0M |
| 36 | Waterfront Employers I L a Welfare Fund Charleston | $22.0M | $17.6M | $12.6M |
| 37 | Rural Health Services INC Aiken | $21.5M | $21.3M | $23.5M |
| 38 | York County Board of Disabilities and Special Needs York | $19.9M | $19.9M | $16.5M |
| 39 | Spc Credit Union Hartsville | $19.8M | $19.8M | $240.7M |
| 40 | Family Health Centers INC Orangeburg | $19.4M | $19.4M | $20.3M |
| 41 | Saluda County Nursing Home Board Saluda Nursing Center Saluda | $19.3M | $19.3M | $12.1M |
| 42 | Pee Dee Community Action Agency Florence | $18.8M | $18.8M | $6.9M |
| 43 | Country Club of Charleston Charleston | $18.3M | $12.8M | $26.3M |
| 44 | South Carolina Farm Bureau Federation Columbia | $18.1M | $10.2M | $58.7M |
| 45 | The Graham Foundation Greenville | $17.9M | $0 | $48.0M |
| 46 | St. Johns Water Company INC Johns Island | $17.5M | $17.5M | $70.2M |
| 47 | Municipal Association of South Carolina Columbia | $17.5M | $17.1M | $37.7M |
| 48 | St. Josephs Catholic School INC Greenville | $17.3M | $16.2M | $18.6M |
| 49 | Blue Ridge Rural Water Company INC Greer | $16.8M | $16.8M | $47.5M |
| 50 | Hospice of the Upstate INC Anderson | $15.7M | $14.1M | $17.7M |