| 1 | Battelle Memorial Institute Columbus | $13.3B | $13.3B | $1.8B |
| 2 | Parallax Advanced Research Corp. Beavercrk Twp | $57.6M | $57.5M | $27.6M |
| 3 | Asm International Novelty | $38.5M | $11.2M | $29.9M |
| 4 | Ohio Aerospace Institute Brookpark | $17.1M | $17.1M | $14.2M |
| 5 | American Society for Nondestructive Testing INC Columbus | $16.8M | $12.5M | $48.4M |
| 6 | Great Lakes Museum of Science Environment and Technology Cleveland | $10.9M | $10.6M | $35.1M |
| 7 | Northwest Ohio Innovation Consortium INC Perrysburg | $10.2M | $10.2M | $10.8M |
| 8 | Institute of Mathematical Statistics Waite Hill | $2.9M | $2.9M | $17.2M |
| 9 | American Conference of Governmental Industrial Hygienists INC Sharonville | $2.8M | $2.8M | $1.1M |
| 10 | Airable Research Lab Worthington | $2.1M | $2.1M | $2.9M |
| 11 | American Chemical Society Akron | $2.1M | $2.1M | $2.8M |
| 12 | State Science and Technology Institute Columbus | $1.7M | $1.7M | $775K |
| 13 | Alliance for Working Together Foundation Mentor | $1.6M | $338K | $2.1M |
| 14 | Precision Metalforming Association Educational Foundation Independence | $934K | $219K | $2.3M |
| 15 | American Peptide Society INC Columbus | $780K | $11K | $1.6M |
| 16 | Women in Manufacturing Education Foundation Cleveland | $768K | $741K | $492K |
| 17 | Asnt Foundation Columbus | $704K | $690K | $6.1M |
| 18 | Mufon Mutual Ufo Network INC Cincinnati | $691K | $637K | $148K |
| 19 | Edueverything INC Caledonia | $535K | $535K | $252K |
| 20 | Toxicology Excellence for Risk Assessment Cincinnati | $454K | $454K | $340K |
| 21 | Microbeam Analysis Society INC Lewisburg | $437K | $153K | $1.0M |
| 22 | Academic Advisory Council for Signage Research and Education INC Cincinnati | $356K | $88K | $2.4M |
| 23 | International Cryogenic Materials Conference Beavercreek | $302K | $0 | $602K |
| 24 | Akron Fossils & Science Center Copley | $296K | $288K | $128K |
| 25 | Ohio Blockchain Council INC Columbus | $227K | $212K | $102K |
| 26 | Black Boys in Tech Cincinnati | $196K | $196K | $120K |
| 27 | Compressed Air Challenge INC Cleveland | $186K | $186K | $82K |
| 28 | Triangle Fraternity National Council Cincinnati | $179K | $179K | $74K |
| 29 | Cleveland Engineering Society Cleveland | $169K | $169K | $190K |
| 30 | Akron Society of Plastics Engineers Educational Foundation North Canton | $168K | $12K | $780K |
| 31 | Global Water Consortium Troy | $149K | $149K | $33K |
| 32 | North American Deer Farmers Assoc Cervid Livestock Foundation Canton | $140K | $115K | $1.3M |
| 33 | The Soul Phone Foundation Chillicothe | $140K | $140K | $49K |
| 34 | Empowe-r Women of Infosec Hilliard | $130K | $66K | $290K |
| 35 | Ohio Natural Energy Foundation Pataskala | $118K | $118K | $649K |
| 36 | National Assoc of Transp Technology Transfer Centers Nashport | $117K | $117K | $135K |
| 37 | Drive Electric Ohio INC Springboro | $87K | $87K | $56K |
| 38 | Chemical Engineering Division of Asee Akron | $82K | $82K | $107K |
| 39 | American Chemical Society Mason | $76K | $69K | $570K |
| 40 | North American Mixing Forum INC Xenia | $60K | $60K | $312K |
| 41 | Asm International Novelty | $60K | $24K | $131K |
| 42 | Tech Community Coalition INC Powell | $53K | $53K | $33K |
| 43 | Ohio Turfgrass Research Trust INC Columbus | $39K | $0 | $470K |
| 44 | Asm International Novelty | $26K | $14K | $136K |
| 45 | Ohio Linuxfest Corporation Powell | $20K | $20K | $40K |
| 46 | Hybrid Autonomous Manufacturing Innovation Corporation Columbus | $16K | $16K | $10K |
| 47 | North American Strawberry Growers Research Foundation INC Ashland | $15K | $15K | $63K |
| 48 | Ohio Robotics INC Dayton | $14K | $14K | $11K |
| 49 | Society for Neuroscience Dayton | $1K | $0 | $4K |
| 50 | Southern Ohio Chapter Human Factors and Ergonomics Society Riverside | $348 | $0 | $3K |