| 1 | Internet Corporation for Assigned Names and Numbers Los Angeles | $617.9M | $184.8M | $599.4M |
| 2 | Sri International Menlo Park | $449.4M | $437.9M | $409.6M |
| 3 | Salk Institute for Biological Studies La Jolla | $448.8M | $161.2M | $822.8M |
| 4 | Navigation Charitable Fund Berkeley | $441.4M | $19.0M | $1.3B |
| 5 | Climateworks Foundation San Francisco | $371.2M | $350.6M | $533.1M |
| 6 | Seti Institute Mountain View | $289.5M | $55.2M | $237.0M |
| 7 | Astera Institute Berkeley | $72.4M | $0 | $2.6B |
| 8 | J Craig Venter Institute INC La Jolla | $70.6M | $14.4M | $39.5M |
| 9 | Simons Laufer Mathematical Sciences Institute Berkeley | $62.6M | $22.5M | $111.1M |
| 10 | Alfred E Mann Foundation for Scientific Research Valencia | $57.1M | $18.1M | $353.4M |
| 11 | Public Library of Science San Francisco | $41.5M | $41.3M | $32.8M |
| 12 | Mozilla Foundation San Francisco | $37.2M | $37.2M | $123.3M |
| 13 | Anita Borg Institute for Women and Technology Sacramento | $35.3M | $27.5M | $23.7M |
| 14 | Schmidt Ocean Institute Palo Alto | $32.8M | $0 | $108.5M |
| 15 | Mind Education Irvine | $31.5M | $31.3M | $37.1M |
| 16 | California Council on Science and Technology Sacramento | $27.4M | $4.2M | $44.4M |
| 17 | Future of Life Foundation Campbell | $25.0M | $25.0M | $25.0M |
| 18 | Far Ai INC San Diego | $24.3M | $24.3M | $23.0M |
| 19 | Hack Foundation W Hollywood | $22.4M | $22.4M | $18.7M |
| 20 | Watttime Corporation Oakland | $21.3M | $21.3M | $10.8M |
| 21 | Gmto Corporation Pasadena | $21.2M | $21.2M | $460.9M |
| 22 | Altasea at the Port of Los Angeles San Pedro | $18.5M | $18.3M | $41.4M |
| 23 | Open Research Lab INC San Francisco | $18.3M | $18.3M | $3.0M |
| 24 | Annual Reviews San Mateo | $17.1M | $17.0M | $6.6M |
| 25 | The Foresight Institute San Francisco | $13.8M | $9.4M | $8.9M |
| 26 | Model Evaluation and Threat Research Covina | $13.6M | $13.6M | $6.5M |
| 27 | Sierra Institute for Community and Taylorsville | $13.3M | $13.3M | $8.7M |
| 28 | Tmt International Observatory LLC Pasadena | $13.2M | $13.2M | $227.9M |
| 29 | Constellation Research Center INC Berkeley | $13.1M | $12.6M | $18.3M |
| 30 | Accumulus Synergy INC Burlingame | $11.1M | $11.1M | $12.3M |
| 31 | Center for Artificial Intelligence Safety INC San Francisco | $10.8M | $10.2M | $12.6M |
| 32 | Public Technical Identifiers Los Angeles | $10.8M | $10.8M | $320K |
| 33 | Society for Advancement of Chicanos & Native Americans in Science INC San Jose | $9.9M | $9.9M | $13.7M |
| 34 | Chabot Space & Science Center Foundation Oakland | $9.8M | $6.4M | $8.8M |
| 35 | Pacific Neuroscience Institute Foundation Santa Monica | $9.7M | $9.7M | $38.8M |
| 36 | Partnership on Ai to Benefit People and Society San Francisco | $9.0M | $9.0M | $8.4M |
| 37 | Spark Ns INC Menlo Park | $9.0M | $9.0M | $3.9M |
| 38 | New Public Oakland | $8.9M | $8.9M | $5.2M |
| 39 | Ought INC Covina | $8.2M | $8.2M | $10.1M |
| 40 | Imec INC San Francisco | $7.9M | $0 | $2.3M |
| 41 | Annual Reviews Investment Corporation San Mateo | $7.6M | $4.5M | $130.2M |
| 42 | International Conference on Machine Learning San Diego | $7.4M | $7.4M | $7.9M |
| 43 | Distributed Artificial Intelligence Research Institute Oakland | $7.1M | $7.1M | $5.7M |
| 44 | Clarity Ai Research INC San Francisco | $6.9M | $6.9M | $6.3M |
| 45 | Meedan INC San Francisco | $6.7M | $6.7M | $4.0M |
| 46 | Foundation for Psycho-cultural Research Pacific Plsds | $6.5M | $0 | $13.7M |
| 47 | Oak Crest Institute of Science Monrovia | $6.5M | $6.5M | $6.0M |
| 48 | Mats Research INC Berkeley | $6.3M | $6.3M | $3.6M |
| 49 | Las Cumbres Observatory Global Telescope Network INC Goleta | $6.1M | $0 | $35.2M |
| 50 | Mind Research Institute INC Irvine | $5.7M | $5.7M | $2.9M |