| 1 | Morgan Stanley Global Impact Funding Trust INC Indianapolis | $6.9B | $3.1B | $9.1B |
| 2 | Renaissance Charitable Foundation INC Indianapolis | $4.6B | $2.4B | $5.9B |
| 3 | Community Foundation of Northwest Indiana INC Munster | $1.6B | $171.9M | $1.8B |
| 4 | Lumina Foundation for Education INC Indianapolis | $644.8M | $0 | $1.5B |
| 5 | Dean & Barbara White Family Foundation INC Merrillville | $357.6M | $0 | $766.3M |
| 6 | Gift Clearing Trust Indianapolis | $320.3M | $145.6M | $145.8M |
| 7 | Ramtell INC Tell City | $278.5M | $0 | $290.0M |
| 8 | Community Foundation of St. Joseph County INC South Bend | $240.6M | $61.3M | $327.4M |
| 9 | Endless Success Foundation INC Indianapolis | $190.7M | $0 | $895.5M |
| 10 | James Whitcomb Riley Memorial Association Indianapolis | $186.7M | $72.8M | $558.2M |
| 11 | Community Foundation of Elkhart County INC Elkhart | $144.1M | $58.8M | $461.3M |
| 12 | Central Indiana Community Foundation INC Indianapolis | $138.3M | $48.5M | $583.5M |
| 13 | Lesea Global Feed the Hungry INC South Bend | $108.7M | $108.1M | $15.5M |
| 14 | Sam Shine Foundation INC Greenville | $88.3M | $0 | $135.9M |
| 15 | Legacy Foundation INC Merrillville | $84.8M | $43.1M | $123.8M |
| 16 | Deborah Joy Simon Foundation Carmel | $79.6M | $0 | $86.4M |
| 17 | Kosciusko 21ST Century Foundation INC Winona Lake | $73.4M | $0 | $62.8M |
| 18 | Community Foundation of Greater Fort Wayne INC Fort Wayne | $70.6M | $33.8M | $245.4M |
| 19 | Community Foundation of Hancock County INC Greenfield | $68.7M | $23.6M | $65.7M |
| 20 | Nina Mason Pulliam Charitable Tr Indianapolis | $62.6M | $0 | $441.1M |
| 21 | United Way of Central Indiana INC Indianapolis | $56.9M | $51.1M | $255.2M |
| 22 | Arthur Dean Family Foundation INC Indianapolis | $55.5M | $0 | $84.5M |
| 23 | Herbert Simon Family Foundation Indianapolis | $55.2M | $0 | $31.1M |
| 24 | The Foundation for the Center for Hospice and Palliative Care INC Mishawaka | $53.6M | $10.8M | $60.5M |
| 25 | Dubois County Community Foundation INC Jasper | $52.2M | $12.1M | $89.6M |
| 26 | Surack Family Foundation INC Fort Wayne | $50.8M | $0 | $47.5M |
| 27 | Community Foundation of Wabash County INC N Manchester | $50.7M | $16.4M | $99.4M |
| 28 | Harrison County Community Foundation Support Organ INC Corydon | $48.0M | $27.0M | $274.5M |
| 29 | Asante Foundation INC South Bend | $47.9M | $0 | $156.7M |
| 30 | Community Foundation Alliance INC Evansville | $42.5M | $18.8M | $149.0M |
| 31 | Elevance Health Foundation INC Indianapolis | $40.2M | $0 | $139.9M |
| 32 | Hamilton County Community Foundation INC Fishers | $39.8M | $23.3M | $129.3M |
| 33 | Foundation for Advanced Philanthrophy Indianapolis | $39.3M | $39.3M | $142.6M |
| 34 | Eskenazi Family Foundation INC Indianapolis | $38.1M | $0 | $16.6M |
| 35 | Crown Point Community Foundation INC Crown Point | $36.2M | $4.9M | $41.3M |
| 36 | Steuben County Community Foundation INC Angola | $36.0M | $11.7M | $64.7M |
| 37 | 8020 Foundation Tr Fort Wayne | $35.1M | $0 | $240.6M |
| 38 | Washington County Community Foundation INC Salem | $34.8M | $10.1M | $41.3M |
| 39 | Samerian Foundation INC Carmel | $33.2M | $0 | $69.3M |
| 40 | Community Foundation of Southern Indiana INC New Albany | $31.9M | $10.5M | $149.1M |
| 41 | Jewish Federation of Greater Indianapolis INC Indianapolis | $31.1M | $8.4M | $108.4M |
| 42 | Marshall County Community Plymouth | $29.1M | $6.1M | $58.0M |
| 43 | Tom and Julie Wood Family Foundation INC Carmel | $26.2M | $0 | $32.6M |
| 44 | Heritage Fund of Bartholomew County INC Columbus | $26.1M | $10.0M | $110.3M |
| 45 | William Lant Ridgway Charitable Trust Evansville | $25.2M | $0 | $33.4M |
| 46 | Sol Foundation INC Carmel | $25.0M | $0 | $24.9M |
| 47 | Brown County Community Foundation INC Nashville | $22.8M | $7.4M | $19.0M |
| 48 | David E Simon & Jacqueline S Simon Charitable Foundation Indianapolis | $22.5M | $0 | $53.4M |
| 49 | Michael a and Connie V Joines Family Foundation INC Granger | $22.3M | $0 | $90.2M |
| 50 | Porter County Community Foundation INC Valparaiso | $21.8M | $18.1M | $110.5M |