| 1 | Haplotace Foundation Birmingham | $348.4M | $0 | $723.8M |
| 2 | The Community Foundation of Greater Birmingham Birmingham | $271.8M | $89.4M | $350.7M |
| 3 | United Way of Central Alabama INC Birmingham | $133.9M | $128.2M | $141.4M |
| 4 | Community Foundation of South Alabama Mobile | $92.7M | $15.4M | $111.4M |
| 5 | Tigers Unlimited Foundation Auburn | $92.1M | $62.5M | $131.2M |
| 6 | Alpha Foundation INC Huntsville | $74.2M | $0 | $47.1M |
| 7 | Lucille S Beeson Charitable Remainder 66 1055001761 Birmingham | $60.6M | $0 | $195.6M |
| 8 | Caring Foundation Hoover | $51.9M | $0 | $81.1M |
| 9 | Regions Foundation Birmingham | $50.4M | $0 | $130.5M |
| 10 | Community Action Partnership of North Alabama INC Decatur | $50.2M | $50.2M | $33.8M |
| 11 | Wiregrass Foundation Dothan | $43.3M | $0 | $114.6M |
| 12 | Michael and Noemi Neidorff Family Foundation Birmingham | $42.5M | $0 | $188.5M |
| 13 | Community Foundation of Northeast Alabama Anniston | $39.6M | $19.6M | $94.4M |
| 14 | Walker Area Community Foundation Jasper | $32.6M | $32.6M | $151.9M |
| 15 | Community Foundation of Greater Huntsville Huntsville | $29.5M | $23.1M | $66.3M |
| 16 | Alabama Power Foundation INC Birmingham | $29.2M | $0 | $117.9M |
| 17 | J L Bedsole Foundation Mobile | $25.4M | $0 | $55.0M |
| 18 | Double Oaks Foundation Birmingham | $24.3M | $0 | $23.4M |
| 19 | Altec-styslinger Foundation INC Birmingham | $23.8M | $0 | $142.9M |
| 20 | Central Alabama Community Foundation INC Montgomery | $22.2M | $19.7M | $106.8M |
| 21 | Zyne Family Foundation INC Birmingham | $20.5M | $0 | $24.2M |
| 22 | Mike and Gillian Goodrich Charitable Foundation Birmingham | $19.0M | $0 | $105.5M |
| 23 | Holle Family Foundation Birmingham | $14.8M | $0 | $51.6M |
| 24 | Rjjb Family Foundation Mobile | $14.4M | $0 | $32.3M |
| 25 | Alfa Foundation Montgomery | $14.1M | $0 | $30.7M |
| 26 | Quarterbacking Childrens Health Foundation Birmingham | $12.6M | $5.9M | $35.4M |
| 27 | Max and Lorayne Cooper Foundation Birmingham | $12.5M | $0 | $25.5M |
| 28 | Joe and Mary Ann Cromeans Charitable Foundation Trust Orange Beach | $12.1M | $0 | $22.5M |
| 29 | Black Belt Community Foundation INC Selma | $11.6M | $11.5M | $26.3M |
| 30 | The Ashurst-lane Family Foundation Montgomery | $9.7M | $0 | $1.0M |
| 31 | Mapp Fam Foundation Tr Point Clear | $8.8M | $0 | $10.3M |
| 32 | Sturgis Charitable Tr Birmingham | $8.7M | $0 | $27.8M |
| 33 | Penny Foundation Birmingham | $8.6M | $8.6M | $829K |
| 34 | Womens Foundation of Alabama Birmingham | $8.5M | $6.0M | $11.7M |
| 35 | Scott Foundation INC Opelika | $8.2M | $0 | $12.4M |
| 36 | Jake F Aronov Charitable Foundation Montgomery | $7.6M | $0 | $9.4M |
| 37 | The J K Lowder Family Foundation Montgomery | $7.5M | $0 | $17.7M |
| 38 | Ewtn Religious Catalogue INC Irondale | $6.9M | $3.1M | $3.6M |
| 39 | E a Roberts Charitable Tr 32-0013-01-4 Mobile | $6.7M | $0 | $32.6M |
| 40 | Lee Bruno Foundation Vestavia | $6.5M | $0 | $11.7M |
| 41 | William Baldwin Yung Charitable Tr 1001022667 Montgomery | $6.4M | $0 | $28.8M |
| 42 | David J Cooper Chartiable Foundation INC Mobile | $6.0M | $0 | $17.5M |
| 43 | Better Place Foundation Irondale | $5.9M | $0 | $11.9M |
| 44 | United Way of West Alabama INC Tuscaloosa | $5.8M | $5.8M | $7.9M |
| 45 | Alabama Family Charitable Tr Vestavia Hls | $5.2M | $1.2M | $6.8M |
| 46 | Cb Foundation INC Mobile | $5.1M | $0 | $42.2M |
| 47 | H G Clay Foundation Spanish Fort | $5.1M | -$8.2M | $3.3M |
| 48 | The Christian Workers Foundation of Alabama INC Harpersville | $4.9M | $0 | $5.7M |
| 49 | Ernest G Debakey Charitable Foundation Saint Elmo | $4.8M | $0 | $16.5M |
| 50 | The Charlie & Moll Anderson Foundation Florence | $4.6M | $0 | $15.9M |