| 1 | South Alabama Medical Science Foundation Mobile | $2.1M | $1.8M | $13.2M |
| 2 | Breast Cancer Research Foundation of Alabama Mountain Brk | $1.6M | $1.5M | $287K |
| 3 | Tuscaloosa Research and Education Advancement Corporation Tuscaloosa | $1.1M | $1.1M | $998K |
| 4 | Gorgas Memorial Institute of Tropic Al and Preventative Medicine INC Birmingham | $966K | $697K | $2.3M |
| 5 | Reed Gastrointestional Oncology Research Foundation Birmingham | $623K | $343K | $581K |
| 6 | Pediatric Heart Transplant Society Foundation Helena | $480K | $480K | $102K |
| 7 | Mycoses Study Group Education and Research Consortium Irondale | $471K | $471K | $477K |
| 8 | Norma Livingston Ovarian Cancer Foundation INC Birmingham | $368K | $325K | $347K |
| 9 | Bashan Institute of Science INC Auburn | $329K | $0 | $1.2M |
| 10 | North Alabama Sickle Cell Foundation INC Huntsville | $220K | $220K | $247K |
| 11 | Professional Association of Social Workers in Hiv & Aids Birmingham | $205K | $205K | $212K |
| 12 | International Institute of Acoustics and Vibration Auburn University | $178K | $178K | $660K |
| 13 | Teal Wings of Hope INC Birmingham | $163K | $154K | $13K |
| 14 | National Organization of Alternative Programs Hoover | $124K | $83K | $252K |
| 15 | Stryker Strong Hoover | $114K | $0 | $27K |
| 16 | Ba Cancer Foundation of Alabama a Non-profit Corporation Vestavia | $110K | $51K | $50K |
| 17 | Racing for Childrens INC Birmingham | $96K | $96K | $391K |
| 18 | Foundation for Spike Protein Long Covid and Microvascular Research I Birmingham | $72K | $72K | $70K |
| 19 | Alabama Branch of the International Dyslexia Association Gurley | $70K | $70K | $91K |
| 20 | Agcsa Foundation Auburn | $67K | $24K | $102K |
| 21 | Blazer Bolt INC Birmingham | $58K | $41K | $24K |
| 22 | Team Rowland INC Hoover | $51K | $51K | $4K |
| 23 | Northeast Alabama Kidney Association INC Gadsden | $50K | $19K | $97K |
| 24 | Rhizokids International Sylacauga | $50K | $50K | $156K |
| 25 | Helen Keller Foundation for Research & Education INC Birmingham | $22K | $22K | $1.5M |
| 26 | Pike County Heart Board Troy | $22K | $20K | $18K |
| 27 | Audie and Kathy White Cancer Research Foundation Trussville | $20K | $20K | $23K |
| 28 | Uab Diabetes Trust Foundation Birmingham | $3K | $3K | $212K |
| 29 | North Alabama Cancer Foundation Huntsville | $1 | $0 | $21K |
| 30 | Bullock County Community Health Advisors Union Springs | $0 | $0 | $0 |
| 31 | American Cancer Research Center and Foundation Dothan | $0 | $0 | $0 |
| 32 | Rosacea Research and Development Institute Centre | $0 | $0 | $0 |
| 33 | B J Green Strike Out Leukemiafoundation Gardendale | $0 | $0 | $0 |
| 34 | Lori C Sasser Foundation INC Tuscumbia | $0 | $0 | $0 |
| 35 | The National Cml Society a K a Carolyns Hope Birmingham | $0 | $0 | $0 |
| 36 | Thomas Plott Foundation INC Tuscaloosa | $0 | $0 | $0 |
| 37 | Jon Lee Foundation Dothan | $0 | $0 | $0 |
| 38 | Styled Vision Outreach Huntsville | $0 | $0 | $0 |
| 39 | Bill Goins Foundation for Cancer Research Huntsville | $0 | $0 | $0 |
| 40 | Commit- Myeloma Trials Innovated Vestavia | $0 | $0 | $0 |
| 41 | A Relationship Company Foundation Birmingham | $0 | $0 | $0 |
| 42 | International Regenerative Design Institute Madison | $0 | $0 | $0 |
| 43 | Alzheimers Research and Care Society Vincent | $0 | $0 | $0 |
| 44 | Heart for Athletes Charitable Trust Mobile | $0 | $0 | $0 |
| 45 | Sherard Shaw Jr Foundation Vestavia | $0 | $0 | $0 |
| 46 | Rethink Metaphysical Genetics Research Lineville | $0 | $0 | $0 |
| 47 | International Childrens Continence Society INC Birmingham | $0 | $0 | $0 |
| 48 | Brothers & Sisters Walk 4 a Cure Aliceville | $0 | $0 | $0 |
| 49 | Team Whip Lanett | $0 | $0 | $0 |
| 50 | United Ostomy Associations of America INC Hoover | $0 | $0 | $0 |