| 1 | International Rescue Committee INC New York | $1.5B | $1.5B | $669.8M |
| 2 | United States Fund for Unicef New York | $845.6M | $835.2M | $514.5M |
| 3 | Medecins Sans Frontieres USA INC New York | $814.9M | $776.9M | $434.3M |
| 4 | Plan International INC New York | $726.9M | $726.9M | $313.9M |
| 5 | Friends of the Israel Defense Forces New York | $608.3M | $187.5M | $384.0M |
| 6 | American Jewish Joint Distribution Committee INC New York | $475.8M | $412.9M | $858.4M |
| 7 | Institute of International Education INC New York | $467.7M | $395.5M | $486.9M |
| 8 | United Israel Appeal INC New York | $465.0M | $464.8M | $172.0M |
| 9 | American Friends of the Hebrew University INC New York | $412.6M | $167.5M | $945.7M |
| 10 | Jewish National Fund -keren Kayemeth Leisrael- INC Rockville Ctr | $406.0M | $224.3M | $633.2M |
| 11 | Catholic Medical Mission Board INC New York | $357.4M | $324.3M | $72.2M |
| 12 | World Education Services INC New York | $294.0M | $139.6M | $259.8M |
| 13 | Project Orbis International INC New York | $270.6M | $259.2M | $74.2M |
| 14 | Arab Gulf Programme for Development New York | $233.6M | $124.3M | $964.7M |
| 15 | Myriad USA INC New York | $229.2M | $200.5M | $123.0M |
| 16 | Hadassah Medical Relief Association INC New York | $212.3M | $50.6M | $679.0M |
| 17 | American Society for Technion- Israel Institute of Technology INC New York | $203.0M | $115.8M | $731.6M |
| 18 | American Friends of Magen David Adom New York | $200.3M | $142.3M | $371.1M |
| 19 | Council on Foreign Relations INC New York | $173.5M | $79.2M | $755.5M |
| 20 | Action Against Hunger USA New York | $161.1M | $160.8M | $81.7M |
| 21 | IBM International Foundation Armonk | $140.2M | $0 | $357.7M |
| 22 | International Aids Vaccine Initiative INC New York | $139.2M | $131.2M | $129.9M |
| 23 | Vital Strategies INC New York | $137.4M | $132.4M | $114.3M |
| 24 | Population Council INC New York | $126.0M | $53.8M | $181.9M |
| 25 | Human Rights Watch INC New York | $124.6M | $77.7M | $219.0M |
| 26 | Romanian American Foundation New York | $100.3M | $2.3M | $149.9M |
| 27 | Central Fund of Israel Cedarhurst | $97.8M | $96.9M | $47.3M |
| 28 | C I S Development Foundation INC New York | $95.7M | $95.7M | $15.6M |
| 29 | Central European University New York | $83.8M | $83.8M | $432.0M |
| 30 | Helen Keller International New York | $83.4M | $75.7M | $157.8M |
| 31 | Citihope International INC Margaretville | $79.5M | $79.5M | $186K |
| 32 | American Jewish World Service INC New York | $79.4M | $44.9M | $78.9M |
| 33 | Birthright Israel Foundation New York | $75.5M | $74.3M | $70.5M |
| 34 | New Israel Fund New York | $74.7M | $55.8M | $53.3M |
| 35 | Amnesty International of the USA INC New York | $67.8M | $61.2M | $57.9M |
| 36 | Association for Cultural Interchange INC New York | $67.7M | $15.9M | $242.2M |
| 37 | Pro Mujer INC New York | $66.7M | $66.7M | $271.8M |
| 38 | Concern Worldwide U S INC New York | $66.6M | $65.7M | $29.6M |
| 39 | American Friends of the Tel Aviv University INC New York | $64.5M | $52.4M | $114.3M |
| 40 | Polish-american Freedom Foundation New York | $63.7M | $12.6M | $318.7M |
| 41 | End Fund INC New York | $62.7M | $62.7M | $38.9M |
| 42 | Interexchange INC New York | $58.9M | $23.0M | $43.5M |
| 43 | Acumen Fund INC New York | $50.1M | $46.4M | $217.5M |
| 44 | American Academy in Rome New York | $48.4M | $22.6M | $169.3M |
| 45 | Foundation for the Global Compact New York | $48.3M | $48.3M | $26.4M |
| 46 | International Planned Parenthood Federation New York | $47.4M | $37.3M | $118.3M |
| 47 | American Committee for the Weizmann Institute of Science INC New York | $47.1M | $35.3M | $993.2M |
| 48 | American Friends of Yeshiva Dmir INC Brooklyn | $44.5M | $42.3M | $13.0M |
| 49 | United Nations Development Corporation New York | $43.7M | $43.7M | $205.6M |
| 50 | Cambridge in America New York | $42.1M | $36.1M | $92.8M |