| 1 | Food for the Poor INC Coconut Creek | $413.8M | $412.1M | $43.0M |
| 2 | Centro International de Agricultura Tropical Incorporated Medley | $153.1M | $153.1M | $183.7M |
| 3 | Hope for Haiti INC Naples | $54.5M | $53.6M | $9.3M |
| 4 | Love a Child INC Fort Myers | $44.5M | $44.5M | $42.6M |
| 5 | Salvadoran American Humanitarian Foundation INC Coral Gables | $34.4M | $34.3M | $1.5M |
| 6 | Instituto Centro Americano de Administracion de Empresas Incae Coral Gables | $34.1M | $34.1M | $84.5M |
| 7 | Unto INC Orlando | $33.7M | $33.7M | $8.8M |
| 8 | Interledger Foundation Tampa | $32.9M | $0 | $97.5M |
| 9 | Advocates for World Health INC Largo | $14.3M | $14.3M | $4.8M |
| 10 | African Mission Healthcare Foundation Deland | $12.2M | $12.1M | $36.4M |
| 11 | Save and Rebuild INC Miami | $11.9M | $11.9M | $11.7M |
| 12 | Rafiki Foundation Incorporated Eustis | $10.4M | $10.2M | $20.1M |
| 13 | Junior Achievement of South Florida Coconut Creek | $9.5M | $9.0M | $20.4M |
| 14 | Favor International INC Valrico | $8.4M | $8.4M | $1.6M |
| 15 | Insulin for Life USA INC Gainesville | $8.2M | $8.2M | $6.5M |
| 16 | Junior Achievement of Tampa Bay Tampa | $8.2M | $8.0M | $17.3M |
| 17 | Outreach Aid to the Americas INC Miami | $7.7M | $7.7M | $349K |
| 18 | Watoto Child Care Ministry INC Tampa | $7.7M | $7.6M | $3.5M |
| 19 | Laboratoria INC Key Biscayne | $7.1M | $1.9M | $11.0M |
| 20 | Clean the World Foundation INC Orlando | $7.0M | $7.0M | $1.4M |
| 21 | Echo INC N Ft Myers | $5.7M | $5.6M | $8.3M |
| 22 | Fuente Latina INC Hollywood | $5.6M | $5.6M | $5.6M |
| 23 | Educate Tomorrow Corp. Miami Shores | $5.3M | $5.3M | $2.9M |
| 24 | Compassion Heritage Foundation INC Jacksonville | $5.2M | $5.2M | $1.6M |
| 25 | Wayuu Taya Foundation INC Riverview | $5.1M | $5.1M | $458K |
| 26 | Revived Soldiers Ukraine Orlando | $4.8M | $4.7M | $8.6M |
| 27 | Alfalit International INC Doral | $4.3M | $4.3M | $2.7M |
| 28 | Operation Lifeshield INC Boynton Beach | $4.3M | $4.3M | $1.1M |
| 29 | Drishtee Foundation Jacksonville | $4.2M | $4.2M | $10.6M |
| 30 | Sea Turtle Conservancy Gainesville | $4.2M | $4.1M | $9.3M |
| 31 | Health Through Walls INC North Miami | $3.7M | $3.7M | $4.0M |
| 32 | Women Win Foundation INC Belleair Blf | $3.6M | $1.5M | $10.1M |
| 33 | Blue Missions Group INC Miami | $3.5M | $3.3M | $613K |
| 34 | Cadena Foundation Hallandle Bch | $3.4M | $3.4M | $322K |
| 35 | Imani Milele Children INC Sebastian | $3.1M | $3.1M | $181K |
| 36 | Okoa Refuge INC Jax Bch | $3.1M | $3.1M | $775K |
| 37 | Giraffe Conservation Foundation USA Orlando | $3.0M | $1.7M | $4.5M |
| 38 | Paluz Corpss Doral | $2.7M | $2.7M | $876K |
| 39 | Global Hope Network International Orlando | $2.7M | $2.7M | $838K |
| 40 | Junior Achievement of Central Florida INC Orlando | $2.7M | $2.5M | $1.9M |
| 41 | Nueva Esperanza- New Hope Girls INC Sarasota | $2.6M | $2.3M | $1.9M |
| 42 | Foundation for Human Rights in Cuba INC Coral Gables | $2.4M | $2.4M | $197K |
| 43 | Indigenous Peoples Technology and Education Center INC Dunnellon | $2.3M | $2.3M | $4.5M |
| 44 | Agape Flights INC Venice | $2.3M | $2.3M | $6.3M |
| 45 | For the Children Ecuador INC Callahan | $2.2M | $2.2M | $2.9M |
| 46 | American International Schools in the Americas INC Doral | $2.1M | $2.1M | $3.0M |
| 47 | Junior Achievement of North Florida Jacksonville | $2.1M | $2.0M | $2.7M |
| 48 | Grace Center Foundation INC Naples | $2.0M | $1.9M | $1.4M |
| 49 | Hope Across the Globe INC Jacksonville | $2.0M | $1.9M | $1.3M |
| 50 | American-haitian Association for Medical Economical & Educational Dover | $1.9M | $1.9M | $617K |