| 1 | The Methodist Hospital Houston | $9.9B | $3.6B | $11.9B |
| 2 | Memorial Hermann Health System Houston | $8.5B | $8.5B | $13.7B |
| 3 | Texas Health Resources Arlington | $4.1B | $1.6B | $9.9B |
| 4 | Texas Childrens Health Plan INC Bellaire | $4.1B | $2.8B | $796.6M |
| 5 | Texas Childrens Hospital Houston | $3.9B | $3.8B | $8.5B |
| 6 | Baylor University Medical Center Dallas | $3.7B | $2.0B | $4.1B |
| 7 | Christus Health Irving | $3.6B | $1.2B | $3.5B |
| 8 | Childrens Health System of Texas Dallas | $2.7B | $2.7B | $5.9B |
| 9 | Cook Childrens Medical Center Fort Worth | $2.2B | $2.2B | $2.5B |
| 10 | Methodist Hospitals of Dallas Dallas | $2.1B | $2.1B | $3.8B |
| 11 | Scott & White Memorial Hospital Dallas | $1.8B | $1.8B | $1.8B |
| 12 | Texas Childrens Hospital Foundation Bellaire | $1.6B | $25.7M | $3.5B |
| 13 | Baylor Regional Medical Center at Grapevine Dallas | $1.5B | $462.7M | $1.5B |
| 14 | Mother Frances Hospital Regional Health Care Center Tyler | $1.4B | $1.4B | $853.3M |
| 15 | Baylor Scott & White Health Dallas | $1.4B | $1.4B | $2.6B |
| 16 | Healthtexas Provider Network Dallas | $1.3B | $1.3B | $286.5M |
| 17 | Scott & White Clinic Dallas | $1.3B | $1.3B | $273.4M |
| 18 | Chi St. Lukes Health Baylor College of Medicine Medical Center Houston | $1.3B | $1.3B | $1.4B |
| 19 | Texas Health Harris Methodist Hospital Fort Worth Fort Worth | $1.3B | $1.3B | $737.9M |
| 20 | Christus Santa Rosa Health Care Corporation San Antonio | $1.2B | $1.2B | $966.7M |
| 21 | Driscoll Childrens Health Plan Corp Christi | $1.2B | $1.2B | $436.0M |
| 22 | Driscoll Childrens Hospital Corp Christi | $1.2B | $1.1B | $2.1B |
| 23 | Christus Trinity Clinic Texas Tyler | $1.1B | $1.1B | $107.7M |
| 24 | Baylor Regional Medical Center at Plano Dallas | $1.1B | $445.3M | $1.2B |
| 25 | Hendrick Medical Center Abilene | $1.0B | $940.8M | $1.7B |
| 26 | Cook Childrens Health Care System Fort Worth | $1.0B | $451.9M | $1.7B |
| 27 | Methodist Hospital Houston | $1.0B | $150.9M | $1.0B |
| 28 | Christus Spohn Health System Corporation Corp Christi | $954.5M | $954.0M | $850.0M |
| 29 | Cook Childrens Health Plan Fort Worth | $929.2M | $892.6M | $334.7M |
| 30 | Baylor All Saints Medical Center Dallas | $888.2M | $693.3M | $768.6M |
| 31 | Texas Health Presbyterian Hospital Dallas Dallas | $869.6M | $869.4M | $468.2M |
| 32 | Texas Scottish Rite Hospital for Children Dallas | $822.6M | $496.2M | $4.4B |
| 33 | Texas Childrens Physician Group Houston | $780.7M | $780.3M | $117.6M |
| 34 | W I Cook Foundation INC Fort Worth | $760.6M | $95.1M | $4.6B |
| 35 | Hillcrest Baptist Medical Center Dallas | $745.2M | $522.0M | $521.8M |
| 36 | Baylor Medical Center at Irving Dallas | $745.1M | $346.4M | $866.3M |
| 37 | Shannon Medical Center San Angelo | $742.2M | $740.3M | $562.5M |
| 38 | Christus Good Shepherd Medical Center Marshall | $697.7M | $696.7M | $396.8M |
| 39 | Scott & White Hospital Round Rock Dallas | $695.9M | $695.9M | $561.7M |
| 40 | Chronic Disease Fund INC Frisco | $656.2M | $493.9M | $220.6M |
| 41 | Texas Health Physicians Group Arlington | $643.7M | $643.5M | $263.0M |
| 42 | United Regional Health Care System INC Wichita Falls | $598.7M | $563.6M | $1.1B |
| 43 | Methodist Healthcare Ministries of South Texas INC San Antonio | $580.0M | $312.1M | $2.2B |
| 44 | Texas Health Presbyterian Hospital Plano Plano | $570.8M | $570.0M | $276.2M |
| 45 | Covenant Medical Center Lubbock | $565.1M | $563.6M | $684.9M |
| 46 | Christus Health Ark-la-tex Texarkana | $538.8M | $538.8M | $226.5M |
| 47 | Christus Health Southeast Texas Beaumont | $533.9M | $533.7M | $276.8M |
| 48 | Cook Childrens Physician Network Fort Worth | $521.6M | $521.6M | $139.4M |
| 49 | Baylor Health Care System Foundation Dallas | $505.5M | $74.6M | $462.2M |
| 50 | St. Joseph Regional Health Center Bryan | $502.3M | $502.3M | $489.3M |