| 1 | Vanderbilt University Medical Center Nashville | $8.0B | $7.7B | $6.6B |
| 2 | St. Jude Childrens Research Hospital INC Memphis | $2.0B | $2.0B | $11.7B |
| 3 | Methodist Healthcare-memphis Memphis | $2.0B | $2.0B | $1.2B |
| 4 | University Health System INC Knoxville | $1.6B | $1.6B | $1.3B |
| 5 | Erlanger Health Chattanooga | $1.3B | $1.3B | $997.0M |
| 6 | Mountain States Health Alliance Johnson City | $1.1B | $1.1B | $603.5M |
| 7 | Baptist Memorial Hospital Memphis | $978.6M | $975.5M | $585.8M |
| 8 | Wellmont Health System Johnson City | $859.1M | $856.9M | $469.6M |
| 9 | Shelby County Health Care Corporation Memphis | $766.8M | $766.8M | $348.5M |
| 10 | Dialysis Clinic INC Nashville | $758.8M | $736.4M | $697.7M |
| 11 | Parkwest Medical Center Knoxville | $473.3M | $469.8M | $289.9M |
| 12 | Methodist Lebonheur Healthcare Memphis | $439.8M | $439.8M | $2.4B |
| 13 | Fort Sanders Regional Medical Center Knoxville | $427.6M | $423.2M | $249.5M |
| 14 | Baptist Memorial Hospital Tipton Covington | $407.3M | $407.1M | $224.4M |
| 15 | Baptist Memorial Health Care Corporation Memphis | $398.1M | $351.2M | $1.7B |
| 16 | East Tennessee Childrens Hospital Association INC Knoxville | $366.4M | $365.4M | $665.5M |
| 17 | Baptist Memorial Hospital - Jonesboro INC Memphis | $288.4M | $288.3M | $288.8M |
| 18 | Baptist Memorial Medical Group INC Memphis | $241.0M | $241.0M | $517.4M |
| 19 | Covenant Health Knoxville | $240.3M | $235.7M | $2.0B |
| 20 | Johnston Memorial Hospital INC Johnson City | $220.4M | $219.5M | $316.6M |
| 21 | Methodist Medical Center Knoxville | $187.1M | $184.4M | $93.7M |
| 22 | Dci Donor Services INC Nashville | $178.3M | $136.0M | $132.1M |
| 23 | Guardian Foundation INC Ooltewah | $173.5M | $173.5M | $129.9M |
| 24 | Mtpc LLC Knoxville | $162.7M | $139.8M | $47K |
| 25 | Morristown Hamblen Hosp Knoxville | $161.8M | $161.2M | $109.8M |
| 26 | Leconte Medical Center Knoxville | $160.4M | $160.4M | $87.7M |
| 27 | Siskin Hospital for Physical Rehabilitation Chattanooga | $156.6M | $55.0M | $157.5M |
| 28 | Wellmont Medical Associates INC Johnson City | $144.6M | $144.2M | $24.0M |
| 29 | Health Services Management INC Murfreesboro | $122.0M | $121.3M | $159.0M |
| 30 | Proton Therapy Center LLC Knoxville | $119.5M | $98.3M | $19K |
| 31 | Takoma Regional Hospital INC Johnson City | $111.4M | $110.8M | $59.9M |
| 32 | Methodist Healthcare-olive Branch Hospital Memphis | $110.2M | $110.2M | $118.0M |
| 33 | Cumberland Medical Center INC Knoxville | $105.7M | $105.2M | $82.7M |
| 34 | Cherokee Health Systems Talbott | $100.1M | $98.9M | $136.8M |
| 35 | Ut Regional One Physicians INC Memphis | $93.1M | $93.1M | $6.8M |
| 36 | Ocoee Foundation INC Cleveland | $90.1M | $90.0M | $91.0M |
| 37 | Ut Le Bonheur Pediatric Specialists INC Memphis | $85.7M | $85.7M | $33.7M |
| 38 | Ut Medical Group INC Memphis | $85.5M | $85.5M | $43.7M |
| 39 | Frontier Health Gray | $84.7M | $83.4M | $64.1M |
| 40 | Ballad Health Johnson City | $80.8M | $81.0M | $2.0B |
| 41 | Music City Prep Clinic Nashville | $79.9M | $79.9M | $34.0M |
| 42 | Sweetwater Hospital Association Sweetwater | $75.4M | $75.4M | $96.3M |
| 43 | Dava Health INC Nashville | $75.2M | $0 | $58.9M |
| 44 | Wellmont Cardiology Services Johnson City | $72.5M | $72.5M | $7.2M |
| 45 | Christ Community Health Services INC Memphis | $63.1M | $61.6M | $25.2M |
| 46 | The Stern Cardiovascular Foundation INC Germantown | $61.3M | $61.3M | $17.8M |
| 47 | Blood Assurance INC Chattanooga | $59.9M | $57.2M | $47.3M |
| 48 | Vine International INC Knoxville | $58.2M | $58.2M | $249K |
| 49 | Baptist Memorial Hospital Union City INC Union City | $55.2M | $54.8M | $32.6M |
| 50 | Unity Medical Center INC Manchester | $54.1M | $54.1M | $56.8M |