| 1 | UPMC Pittsburgh | $8.3B | $772.2M | $10.0B |
| 2 | The Childrens Hospital of Philadelphia Philadelphia | $3.9B | $3.9B | $8.1B |
| 3 | Lehigh Valley Hospital Allentown | $3.8B | $3.2B | $3.6B |
| 4 | Miltons S Hershey Medical Center Hershey | $2.9B | $2.9B | $3.8B |
| 5 | Thomas Jefferson University Hospital Philadelphia | $2.6B | $2.6B | $2.5B |
| 6 | Temple University Hospital INC Philadelphia | $2.3B | $2.3B | $1.6B |
| 7 | York Hospital York | $2.2B | $1.7B | $2.6B |
| 8 | Geisinger Medical Center Danville | $2.0B | $2.0B | $5.6B |
| 9 | UPMC Pittsburgh | $2.0B | $1.6B | $1.0B |
| 10 | Geisinger Clinic Danville | $1.9B | $1.9B | $5.4B |
| 11 | Main Line Hospitals INC Radnor | $1.7B | $1.7B | $3.1B |
| 12 | Lancaster General Hospital Lancaster | $1.6B | $1.6B | $1.2B |
| 13 | St. Lukes Hospital Bethlehem | $1.6B | $1.6B | $3.6B |
| 14 | Reading Hospital West Reading | $1.5B | $1.5B | $1.0B |
| 15 | Presbyterian Medical Center of the University of Pennsylvania Health Philadelphia | $1.3B | $1.3B | $968.4M |
| 16 | The Childrens Hospital of Philadelphia Foundation Philadelphia | $1.1B | $325.6M | $4.9B |
| 17 | Geisinger Wyoming Valley Medical Center Danville | $1.0B | $1.0B | $868.5M |
| 18 | Lehigh Valley Physician Group Allentown | $1.0B | $1.0B | $423.3M |
| 19 | Wellspan Medical Group York | $1.0B | $1.0B | $148.3M |
| 20 | Penn State Health Hershey | $979.4M | $866.0M | $1.6B |
| 21 | Abington Memorial Hospital Abington | $879.5M | $877.9M | $747.5M |
| 22 | Pennsylvania Hospital of the Univ of Pennsylvania Health System Philadelphia | $852.8M | $852.7M | $844.6M |
| 23 | Wellspan Health York | $846.0M | $844.6M | $697.2M |
| 24 | Geisinger System Services Danville | $837.0M | $836.9M | $2.7B |
| 25 | Kennedy University Hospital INC Philadelphia | $817.2M | $817.0M | $1.3B |
| 26 | Mount Nittany Medical Center State College | $780.5M | $539.8M | $1.4B |
| 27 | Robert Packer Hospital Sayre | $779.6M | $578.8M | $1.5B |
| 28 | Jefferson Health-northeast Philadelphia | $693.3M | $693.1M | $1.6B |
| 29 | Lehigh Valley Hospital Pocono Allentown | $691.9M | $531.2M | $865.2M |
| 30 | Chambersburg Hospital York | $630.7M | $520.0M | $561.5M |
| 31 | Highmark Health Pittsburgh | $602.9M | $602.6M | $676.7M |
| 32 | UPMC Pittsburgh | $576.7M | $575.9M | $114.3M |
| 33 | Dubois Regional Medical Center Du Bois | $575.9M | $498.3M | $600.2M |
| 34 | Community Medical Center Danville | $562.0M | $561.5M | $449.4M |
| 35 | Main Line Healthcare Radnor | $527.9M | $527.9M | $181.3M |
| 36 | Chester County Hospital West Chester | $507.4M | $507.4M | $530.5M |
| 37 | Guthrie Medical Group Pc Sayre | $506.9M | $486.1M | $736.6M |
| 38 | St. Lukes Hospital Anderson Campus Allentown | $499.6M | $499.4M | $563.5M |
| 39 | Gettysburg Hospital York | $475.8M | $381.7M | $555.0M |
| 40 | Tower Health Reading | $444.2M | $406.6M | $1.6B |
| 41 | Temple Faculty Practice Plan INC Philadelphia | $418.1M | $418.1M | $104.2M |
| 42 | UPMC Pittsburgh | $417.8M | $417.8M | $289.9M |
| 43 | St. Mary Medical Center Langhorn | $411.1M | $411.1M | $992.3M |
| 44 | UPMC Western Maryland Corporation Pittsburgh | $409.0M | $407.0M | $323.6M |
| 45 | Heritage Valley Health System INC Sewickley | $401.4M | $401.4M | $478.3M |
| 46 | Doylestown Hospital Doylestown | $380.7M | $380.7M | $450.3M |
| 47 | Meadville Medical Center Meadville | $367.1M | $271.3M | $301.5M |
| 48 | Holy Redeemer Health System Meadowbrook | $365.6M | $353.5M | $481.7M |
| 49 | Stc Healthcare Partners LLC Reading | $364.0M | $364.0M | $231.8M |
| 50 | The American Oncologic Hospital Philadelphia | $363.0M | $348.1M | $251.7M |