| 1 | Cleveland Clinic Foundation Independence | $20.0B | $17.2B | $26.5B |
| 2 | Caresource Ohio INC Dayton | $15.4B | $8.6B | $2.2B |
| 3 | Bon Secours Mercy Health INC Blue Ash | $11.5B | $11.5B | $14.4B |
| 4 | The Cleveland Clinic Foundation Cleveland | $10.8B | $9.7B | $17.4B |
| 5 | Ohiohealth Corporation Grant Riverside Doctors Dublin Met Columbus | $7.9B | $5.1B | $10.2B |
| 6 | University Hospitals Health System INC Shaker Hts | $5.9B | $5.9B | $3.3B |
| 7 | Childrens Hospital Medical Center Cincinnati | $4.6B | $3.4B | $10.0B |
| 8 | Childrens Hospital Medical Center of Akron Akron | $2.7B | $1.5B | $2.5B |
| 9 | Caresource Indiana INC Dayton | $2.7B | $1.3B | $437.4M |
| 10 | Uc Healthcare System Cincinnati | $2.6B | $2.6B | $1.8B |
| 11 | Ohiohealth Corporation Columbus | $2.3B | $2.2B | $1.7B |
| 12 | Caresource Georgia Co Dayton | $2.3B | $1.5B | $657.1M |
| 13 | Bon Secours Richmond Health System Cincinnati | $2.1B | $2.0B | $0 |
| 14 | Miami Valley Hospital Dayton | $1.9B | $1.6B | $1.5B |
| 15 | Toledo Hospital Toledo | $1.8B | $1.7B | $1.8B |
| 16 | Nationwide Childrens Hospital INC Columbus | $1.6B | $1.6B | $428.7M |
| 17 | Caresource Dayton | $1.5B | $1.5B | $2.8B |
| 18 | Christ Hospital Cincinnati | $1.4B | $1.4B | $1.4B |
| 19 | Kettering College Miamisburg | $1.2B | $1.2B | $1.5B |
| 20 | Bethesda Hospital INC Cincinnati | $1.1B | $917.3M | $1.3B |
| 21 | Aultman Health Foundation Group Return Canton | $1.1B | $1.0B | $545.6M |
| 22 | The Good Samaritan Hospital of Cincinnati Ohio Dtd 01251995 Cincinnati | $983.3M | $969.0M | $1.2B |
| 23 | Adena Health System Chillicothe | $968.9M | $704.4M | $798.3M |
| 24 | University Hospitals Health System INC Shaker Hts | $954.9M | $954.8M | $5.8B |
| 25 | Dayton Osteopathic Hospital Miamisburg | $870.4M | $870.3M | $877.4M |
| 26 | Dayton Childrens Hospital Dayton | $836.6M | $741.3M | $1.8B |
| 27 | Caresource West Virginia Co Dayton | $802.0M | $214.7M | $139.6M |
| 28 | Genesis Healthcare System Zanesville | $761.7M | $759.9M | $728.1M |
| 29 | Southern Ohio Medical Center Portsmouth | $685.8M | $586.4M | $624.7M |
| 30 | Childrens Hospital Cincinnati | $625.3M | $240.5M | $5.4B |
| 31 | Mount Carmel Health Plan INC Columbus | $598.5M | $598.5M | $501.8M |
| 32 | Southwest General Health Center Cleveland | $541.1M | $449.6M | $523.6M |
| 33 | Marietta Memorial Hospital Marietta | $535.9M | $518.2M | $736.6M |
| 34 | Community Mercy Health Partners Springfield | $523.2M | $392.5M | $381.2M |
| 35 | Blanchard Valley Regional Health Center Findlay | $461.2M | $413.7M | $677.3M |
| 36 | Summa Health Akron | $454.2M | $268.0M | $978.6M |
| 37 | Licking Memorial Hospital Newark | $402.9M | $399.2M | $228.0M |
| 38 | Caresource Kentucky Co Dayton | $390.0M | $172.8M | $56.3M |
| 39 | Fairfield Medical Center Lancaster | $372.6M | $351.6M | $281.9M |
| 40 | Firelands Regional Medical Center Sandusky | $355.7M | $313.6M | $527.5M |
| 41 | Atrium Medical Center Dayton | $348.3M | $280.3M | $275.1M |
| 42 | Heartland Health & Wellness Fund Dayton | $347.8M | $347.8M | $40.9M |
| 43 | Community Blood Center Dayton | $344.1M | $303.0M | $541.6M |
| 44 | Promedica Central Physicians LLC Toledo | $338.7M | $338.3M | $129.4M |
| 45 | Galion Community Hospital Galion | $321.3M | $320.3M | $188.7M |
| 46 | Lima Memorial Joint Operating Company Lima | $318.1M | $317.9M | $604.1M |
| 47 | Hcr Manorcare INC Toledo | $304.4M | $304.4M | $570.5M |
| 48 | Beavercreek Medical Center Miamisburg | $292.8M | $292.8M | $273.9M |
| 49 | Promedica Health System INC Toledo | $273.7M | $268.6M | $910.3M |
| 50 | Trihealth Physician Enterprises Corp. Cincinnati | $269.2M | $269.2M | $105.7M |