| 1 | Mayo Clinic Rochester | $20.8B | $7.9B | $26.7B |
| 2 | Mayo Clinic Group Return Rochester | $14.9B | $14.9B | $17.9B |
| 3 | Ucare Minnesota Minneapolis | $7.1B | $6.3B | $1.5B |
| 4 | Allina Health System Minneapolis | $6.8B | $5.9B | $6.0B |
| 5 | Fairview Health Services Minneapolis | $6.1B | $5.3B | $6.5B |
| 6 | Childrens Health Care Minneapolis | $2.2B | $1.2B | $1.9B |
| 7 | Hennepin Healthcare System INC Minneapolis | $1.7B | $1.7B | $816.7M |
| 8 | Group Health INC Bloomington | $1.5B | $1.5B | $1.7B |
| 9 | North Memorial Health Care Robbinsdale | $1.4B | $998.7M | $713.0M |
| 10 | St. Cloud Hospital Saint Cloud | $1.2B | $1.1B | $1.4B |
| 11 | Regions Hospital Bloomington | $1.1B | $1.1B | $1.2B |
| 12 | University of Minnesota Physicians Minneapolis | $906.9M | $903.0M | $286.8M |
| 13 | Smdc Medical Center Duluth | $797.6M | $796.4M | $1.1B |
| 14 | National Marrow Donor Program Minneapolis | $781.2M | $666.7M | $402.7M |
| 15 | St. Marys Medical Center Duluth | $647.7M | $563.8M | $1.0B |
| 16 | Centracare Health System Saint Cloud | $600.9M | $577.8M | $1.2B |
| 17 | Healtheast St. Johns Hospital Minneapolis | $522.1M | $521.8M | $193.7M |
| 18 | Essentia Health Duluth | $502.2M | $369.9M | $869.7M |
| 19 | Gillette Childrens Specialty Health Care Saint Paul | $443.6M | $396.6M | $514.2M |
| 20 | Ridgeview Medical Center Waconia | $409.5M | $407.1M | $402.1M |
| 21 | St. Joseph S Medical Center Brainerd | $360.6M | $292.1M | $438.5M |
| 22 | Centracare Clinic Saint Cloud | $319.3M | $319.1M | $62.7M |
| 23 | Olmsted Medical Center Rochester | $312.7M | $304.8M | $311.5M |
| 24 | Maple Grove Hospital Corporation Maple Grove | $302.6M | $302.6M | $151.1M |
| 25 | Duluth Clinic Ltd Duluth | $299.3M | $277.6M | $137.3M |
| 26 | St. Lukes Hospital of Duluth Duluth | $272.1M | $270.4M | $536.1M |
| 27 | St. Francis Regional Medical Center Minneapolis | $268.0M | $239.3M | $276.7M |
| 28 | Healtheast Woodwinds Hospital Minneapolis | $228.6M | $228.5M | $124.1M |
| 29 | Park Nicollet Health Services St. Louis Park | $226.5M | $226.5M | $267.3M |
| 30 | Cuyuna Regional Medical Center Crosby | $214.8M | $213.9M | $110.4M |
| 31 | St. Marys Regional Health Center Detroit Lakes | $201.9M | $181.5M | $208.7M |
| 32 | Lakeview Memorial Hospital Association INC Stillwater | $192.9M | $192.9M | $147.3M |
| 33 | Lake Region Healthcare Corporation Fergus Falls | $186.5M | $168.5M | $158.3M |
| 34 | University of Minnesota Health Clinics and Surgery Center INC Minneapolis | $173.0M | $173.0M | $114.5M |
| 35 | Healtheast Medical Research Institute Minneapolis | $171.3M | $171.3M | $40.8M |
| 36 | Ani Rare Disease Patient Assistance Program INC Baudette | $167.6M | $0 | $6.5M |
| 37 | Lakewood Health System Staples | $163.0M | $162.9M | $206.8M |
| 38 | Welia Health Mora | $156.6M | $138.2M | $201.1M |
| 39 | Avera Marshall Marshall | $151.4M | $151.4M | $101.6M |
| 40 | Medica Community Health Plan Minnetonka | $149.5M | $134.5M | $138.2M |
| 41 | Range Regional Health Services Hibbing | $141.0M | $141.0M | $99.4M |
| 42 | Grand Itasca Clinic and Hospital Grand Rapids | $140.9M | $140.2M | $104.9M |
| 43 | Aitkin Community Hospital INC Aitkin | $124.9M | $104.6M | $172.3M |
| 44 | Winona Health Services Winona | $110.7M | $110.5M | $111.2M |
| 45 | Hutchinson Health Hutchinson | $107.0M | $106.4M | $112.1M |
| 46 | Glencoe Regional Health Services Glencoe | $105.8M | $94.0M | $131.0M |
| 47 | Upper Midwest Organ Procurement Organization INC Minneapolis | $93.0M | $82.5M | $75.1M |
| 48 | Benedictine Health System Minneapolis | $82.7M | $82.5M | $185.7M |
| 49 | Critical Care Services INC Shoreview | $80.3M | $62.5M | $78.0M |
| 50 | Lifecare Medical Center Roseau | $75.3M | $75.0M | $121.0M |