| 1 | Advocate Health and Hospitals Corporation Downers Grove | $12.9B | $7.8B | $23.8B |
| 2 | Northwestern Memorial Healthcare Chicago | $10.1B | $10.1B | $14.2B |
| 3 | Ann & Robert H Lurie Childrens Hospital of Chicago Chicago | $6.1B | $1.5B | $3.6B |
| 4 | Osf Healthcare System Peoria | $3.9B | $3.9B | $5.8B |
| 5 | Rush University Medical Center Chicago | $3.9B | $3.0B | $4.7B |
| 6 | Northshore University Healthsystem Arlington Hts | $3.8B | $2.3B | $6.8B |
| 7 | University of Chicago Medical Center Chicago | $3.8B | $3.2B | $4.8B |
| 8 | Northwestern Memorial Healthcare Chicago | $2.3B | $2.3B | $15.2B |
| 9 | Loyola University Medical Center Maywood | $1.7B | $1.7B | $4.2B |
| 10 | The Carle Foundation Hospital Urbana | $1.6B | $1.5B | $651.5M |
| 11 | Advocate North Side Health Network Downers Grove | $1.4B | $1.4B | $1.7B |
| 12 | Copley Memorial Hospital INC Aurora | $1.0B | $458.0M | $1.2B |
| 13 | Southern Illinois Hospital Services Carbondale | $1.0B | $765.6M | $1.5B |
| 14 | The Carle Foundation Urbana | $945.7M | $693.3M | $3.3B |
| 15 | Edward Hospital Arlington Hts | $908.5M | $908.3M | $704.6M |
| 16 | Swedishamerican Hospital Rockford | $896.2M | $888.1M | $1.2B |
| 17 | Riverside Medical Center Kankakee | $877.9M | $528.8M | $833.5M |
| 18 | Javon Bea Hospital Rockford | $863.6M | $465.1M | $774.0M |
| 19 | Blessing Hospital Quincy | $858.3M | $704.7M | $806.6M |
| 20 | Sarah Bush Lincoln Health Center Mattoon | $747.5M | $626.2M | $1.2B |
| 21 | St. Vincent Hospital of the Hospital Sisters of the Third Order of St. Springfield | $739.9M | $739.7M | $918.9M |
| 22 | Endeavor Health Medical Group Arlington Hts | $658.0M | $658.0M | $280.5M |
| 23 | Rehabilitation Institute of Chicago Chicago | $656.6M | $446.7M | $1.3B |
| 24 | Advocate Health Care Network Downers Grove | $643.2M | $643.1M | $698.0M |
| 25 | Northwest Community Hospital Arlington Hts | $634.6M | $633.8M | $521.7M |
| 26 | St. George Corporation Burr Ridge | $616.6M | $0 | $808.3M |
| 27 | St. Johns Hospital of the Hospital Sisters of the Third Order of St. F Springfield | $607.8M | $601.6M | $593.7M |
| 28 | Silver Cross Hospital & Medical Centers New Lenox | $587.8M | $587.8M | $1.1B |
| 29 | Hospital Sisters Health System Springfield | $577.8M | $577.8M | $582.8M |
| 30 | Adventist Midwest Health Hinsdale | $574.9M | $574.7M | $556.2M |
| 31 | Methodist Medical Center of Illinois Urbana | $564.4M | $498.0M | $278.0M |
| 32 | Advocate Sherman Hospital Downers Grove | $562.1M | $561.7M | $477.7M |
| 33 | Trinity Medical Center Rock Island | $527.8M | $477.9M | $482.1M |
| 34 | Osf Multi-specialty Group Peoria | $475.3M | $475.1M | $191.3M |
| 35 | Mount Sinai Hospital Medical Center Chicago | $428.3M | $428.3M | $318.2M |
| 36 | Ingalls Memorial Hospital Harvey | $388.8M | $387.9M | $435.7M |
| 37 | Carle Health Care Incorporated Urbana | $355.0M | $355.0M | $69.6M |
| 38 | Memorial Health System Springfield | $337.3M | $226.8M | $619.6M |
| 39 | St. Elizabeths Hospital of the Hospital Sisters of the Third Orde Springfield | $307.8M | $305.4M | $326.7M |
| 40 | Anderson Hospital Maryville | $296.1M | $229.2M | $258.5M |
| 41 | Morris Hospital Morris | $284.3M | $277.6M | $386.6M |
| 42 | Ottawa Regional Hospital & Healthcare Center Peoria | $272.0M | $269.6M | $221.7M |
| 43 | Carle Bromenn Medical Center Urbana | $267.6M | $267.4M | $66.0M |
| 44 | Lurie Childrens Medical Group INC Chicago | $267.5M | $267.5M | $27.0M |
| 45 | Gottlieb Community Health Services Corporation Melrose Park | $254.6M | $254.6M | $1.9B |
| 46 | Rush Oak Park Hospital INC Oak Park | $240.7M | $209.4M | $195.6M |
| 47 | National Council of State Boards of Nursing INC Chicago | $236.4M | $144.0M | $325.7M |
| 48 | Thorek Memorial Hospital Chicago | $233.2M | $136.2M | $618.7M |
| 49 | Joint Commission on Accreditation of Healthcare Organizations Oakbrook Ter | $227.9M | $222.3M | $434.1M |
| 50 | Ronald McDonald House Global Chicago | $227.6M | $144.0M | $303.2M |