| 1 | Augustana University Association Sioux Falls | $157.6M | $123.9M | $361.9M |
| 2 | University of South Dakota Foundation Vermillion | $136.7M | $38.2M | $367.5M |
| 3 | South Dakota State University Foundation Brookings | $77.5M | $73.3M | $411.9M |
| 4 | University of Sioux Falls Sioux Falls | $55.7M | $41.1M | $96.4M |
| 5 | Dakota State University Foundation Madison | $55.2M | $10.2M | $102.2M |
| 6 | Oglala Lakota College Kyle | $50.2M | $49.6M | $144.2M |
| 7 | Sdsm&t Center for Alumni Relations & Advancement Rapid City | $49.4M | $29.3M | $176.2M |
| 8 | Mount Marty University Yankton | $39.7M | $34.7M | $76.4M |
| 9 | Dakota Wesleyan University Mitchell | $29.4M | $29.3M | $89.3M |
| 10 | Little Wound School Board INC Kyle | $27.7M | $27.5M | $26.8M |
| 11 | Black Hills State University Foundation Spearfish | $26.3M | $19.9M | $50.7M |
| 12 | Sicangu Oyate Ho INC Saint Francis | $19.3M | $19.1M | $38.6M |
| 13 | Sioux Falls Christian Schools Association Sioux Falls | $19.2M | $17.8M | $44.2M |
| 14 | Tiospa Zina Tribal School Agency Vlg | $13.4M | $13.4M | $18.1M |
| 15 | Ssomusd Residency Corporation Sioux Falls | $13.1M | $13.1M | $1.2M |
| 16 | Great Plains Education Foundation INC Aberdeen | $12.9M | $0 | $30.9M |
| 17 | Waitt Foundation N Sioux City | $10.7M | $0 | $136.3M |
| 18 | University of South Dakota Research Park INC Sioux Falls | $10.4M | $10.4M | $22.7M |
| 19 | Presentation College Aberdeen | $10.1M | $10.1M | $2.3M |
| 20 | Crazy Horse School Wanblee | $9.4M | $9.2M | $9.4M |
| 21 | Black Spring Foundation INC Sioux Falls | $8.4M | $0 | $20.4M |
| 22 | Loneman School Corporation Oglala | $8.2M | $8.2M | $10.6M |
| 23 | Marty Indian School Board INC Marty | $7.8M | $7.8M | $26.1M |
| 24 | C H Robinson Worldwide Foundation Sioux Falls | $7.7M | $0 | $18.2M |
| 25 | Via-bradely College of Engineering Foundation Sioux Falls | $6.7M | $0 | $30.8M |
| 26 | Central States Fair Rapid City | $5.9M | $5.1M | $1.9M |
| 27 | Black Hills Educational Institute INC Rapid City | $5.5M | $5.5M | $18K |
| 28 | Center for Family Medicine Sioux Falls | $5.1M | $5.1M | $6.3M |
| 29 | South Dakota Partners in Education Sioux Falls | $5.1M | $5.1M | $1.5M |
| 30 | Wounded Knee District School Manderson | $5.0M | $5.0M | $7.2M |
| 31 | Lake Area Technical College Foundation Watertown | $5.0M | $4.5M | $11.4M |
| 32 | Rapid City Christian Education Association INC Rapid City | $4.5M | $4.5M | $10.3M |
| 33 | Oahe Child Development Center INC Pierre | $3.2M | $3.2M | $2.4M |
| 34 | Freeman Academy & Freeman Junior College Freeman | $2.6M | $2.3M | $4.8M |
| 35 | Sicangu Owayawa Oti-rosebud Dormitory Mission | $2.5M | $2.5M | $5.2M |
| 36 | Sunshine Bible Academy Miller | $2.2M | $2.2M | $6.3M |
| 37 | Pierre School District No 32-2 Educational Foundation Pierre | $2.1M | $441K | $3.9M |
| 38 | Aberdeen Christian School INC Aberdeen | $1.9M | $1.9M | $834K |
| 39 | Research Park at Sdsu Brookings | $1.7M | $1.7M | $38.7M |
| 40 | Mitchell Technical Institute Foundation Mitchell | $1.7M | $1.7M | $7.2M |
| 41 | Christian Center Day Care INC Sioux Falls | $1.7M | $1.7M | $210K |
| 42 | Luther House of Study Sioux Falls | $1.6M | $1.6M | $1.4M |
| 43 | Dakota Rural Action Brookings | $1.5M | $1.5M | $1.6M |
| 44 | South Dakota State University Alumni Association Brookings | $1.4M | $1.4M | $842K |
| 45 | Southeast Technical Institute Foundation Sioux Falls | $1.3M | $1.3M | $2.8M |
| 46 | Friends of Levitt Shell Sioux Falls INC Sioux Falls | $1.3M | $1.3M | $2.7M |
| 47 | Lower Brule Community College INC Lower Brule | $1.2M | $1.2M | $1.9M |
| 48 | Mitchell Christian Education Association Mitchell | $1.2M | $1.2M | $3.2M |
| 49 | Black Hills Christian Academy Spearfish | $1.1M | $1.1M | $1.3M |
| 50 | Ihanktonwan Community College Marty | $985K | $985K | $3.3M |