| 1 | Cascade Aids Project Portland | $30.2M | $29.6M | $19.5M |
| 2 | United Cerebral Palsy Assoc of Oreg on and Southwest Washington INC Portland | $15.9M | $13.8M | $10.6M |
| 3 | Housecall Providers Pc Portland | $11.8M | $11.8M | $4.7M |
| 4 | Community Cancer Foundation Community Cancer Center Roseburg | $5.7M | $5.7M | $14.6M |
| 5 | Vinnova Portland | $4.4M | $4.4M | $1.6M |
| 6 | Oregon Lions Sight and Hearing Foundation INC Portland | $2.2M | $2.0M | $8.1M |
| 7 | Pediatric Dermatology Research Alliance INC Portland | $1.8M | $1.8M | $1.6M |
| 8 | Set Foundation INC Lake Oswego | $1.6M | $1.6M | $145K |
| 9 | Mederi Foundation Ashland | $1.6M | $1.6M | $450K |
| 10 | Lifestyle Medicine Foundation Salem | $1.5M | $1.5M | $501K |
| 11 | Estuary Center Portland | $1.4M | $1.4M | $463K |
| 12 | North American Board of Naturopathic Examiners Portland | $1.2M | $1.2M | $1.4M |
| 13 | A Hope for Autism Foundation Portland | $996K | $996K | $151K |
| 14 | Clear Vision Foundation Eugene | $972K | $972K | $225K |
| 15 | Western Society of Allergy Asthma & Portland | $901K | $901K | $2.6M |
| 16 | Thymic Carcinoma Center Portland | $895K | $895K | $335K |
| 17 | Dream Drives for Kids Portland | $802K | $0 | $4.7M |
| 18 | Brian Grant Foundation Portland | $782K | $746K | $1.3M |
| 19 | Society for Inherited Metabolic Disorders West Linn | $761K | $761K | $1.1M |
| 20 | Vestibular Disorders Association Portland | $747K | $743K | $721K |
| 21 | Lyme Disease Biobank Foundation Portland | $746K | $746K | $281K |
| 22 | Program for Intellectual Empowerment Portland | $730K | $730K | $176K |
| 23 | Assist Portland | $670K | $670K | $305K |
| 24 | Spondyloarthritis Research and Treatment Network Portland | $669K | $669K | $2.4M |
| 25 | US Human Proteome Organization Portland | $546K | $546K | $997K |
| 26 | Central Oregon Disablility Support Network INC Bend | $522K | $522K | $138K |
| 27 | Nplex Portland | $496K | $496K | $1.5M |
| 28 | Michelles Love Scappoose | $491K | $491K | $412K |
| 29 | The Blosser Center for Dyslexia Resources Portland | $466K | $466K | $585K |
| 30 | Breast Friends Tigard | $464K | $406K | $680K |
| 31 | Multicultural Integrated Kidney Education Program Portland | $413K | $399K | $137K |
| 32 | Fidgetech West Linn | $394K | $394K | $415K |
| 33 | Project Koru Hood River | $383K | $383K | $115K |
| 34 | Josh Bidwell Foundation Winston | $340K | $340K | $193K |
| 35 | Hull Foundation and Learning Center INC Sandy | $329K | $232K | $2.3M |
| 36 | Tater Tots Pediatric Therapy Klamath Falls | $326K | $326K | $78K |
| 37 | Autism Family Support of Rural Clackamas County Damascus | $247K | $247K | $213K |
| 38 | Ok You INC Portland | $235K | $233K | $8K |
| 39 | Fighting Pretty INC Portland | $219K | $209K | $135K |
| 40 | Vivian Lee Foundation Newberg | $197K | $195K | $46K |
| 41 | Northwest Kidney Council Lake Oswego | $197K | $197K | $43K |
| 42 | Light Collective INC Eugene | $169K | $169K | $116K |
| 43 | International College of Cranio-mandibular Cannon Beach | $168K | $168K | $317K |
| 44 | For Him Today INC Salem | $165K | $85K | $75K |
| 45 | Brees Foundation for Breast Cancer Research Bandon | $165K | $165K | $34K |
| 46 | Mec Disabilities Grants Pass | $162K | $161K | $19K |
| 47 | Multiple Sclerosis Society of Portland Oregon INC Portland | $154K | $70K | $71K |
| 48 | Down Syndrome Network Oregon Lake Oswego | $154K | $120K | $153K |
| 49 | Sherie Hildreth Ovarian Cancer Foundation Portland | $148K | $34K | $169K |
| 50 | Raiden Science Foundation Beaverton | $137K | $135K | $632K |