| 1 | American Academy of Neurology Institute Minneapolis | $73.6M | $38.8M | $130.2M |
| 2 | Childrens Clinic Network Minneapolis | $34.6M | $34.6M | $15.1M |
| 3 | Autism Opportunities Foundation Minnetonka | $32.8M | $29.4M | $23.0M |
| 4 | Child Neurology Society Roseville | $10.3M | $3.7M | $5.9M |
| 5 | Epilepsy Foundation of Minnesota INC Bloomington | $9.1M | $2.1M | $8.5M |
| 6 | Ronald McDonald House Charities Upper Midwest Minneapolis | $8.4M | $8.1M | $31.3M |
| 7 | Peripheral Nerve Society Roseville | $6.2M | $2.2M | $8.4M |
| 8 | Starkey Hearing Foundation Eden Prairie | $5.6M | $0 | $3.6M |
| 9 | Minnesota Brain Injury Alliance Roseville | $5.4M | $5.4M | $6.9M |
| 10 | Angel Foundation Mendota Hts | $5.0M | $3.4M | $5.2M |
| 11 | Colon Cancer Coalition Foundation Minneapolis | $4.5M | $2.2M | $5.5M |
| 12 | Lighthouse Center for Vital Living Duluth | $3.3M | $1.6M | $6.3M |
| 13 | Never Surrender INC Hermantown | $2.9M | $2.7M | $2.1M |
| 14 | American Indian Cancer Foundation Saint Paul | $2.4M | $2.4M | $1.5M |
| 15 | Lung Cancer Foundation of America New Ulm | $2.4M | $2.3M | $2.1M |
| 16 | Sexual Medicine Society of North America Burnsville | $2.3M | $2.3M | $10.2M |
| 17 | North American Neuro-opthalmology Society Roseville | $2.2M | $2.2M | $4.4M |
| 18 | Jacks Basket Arden Hills | $1.7M | $1.5M | $1.7M |
| 19 | Midwest Kidney Network Saint Paul | $1.7M | $1.4M | $2.9M |
| 20 | Steve Rummler Hope Network Saint Paul | $1.7M | $1.6M | $914K |
| 21 | Becker County Developmental Achievement Center INC Detroit Lakes | $1.5M | $1.4M | $1.7M |
| 22 | Friends of Ngong Road Minneapolis | $1.4M | $1.1M | $2.7M |
| 23 | American Council of the Blind Enterprises and Services INC Brooklyn Center | $1.3M | $1.3M | $1.3M |
| 24 | A Breath of Hope Lung Foundation Bloomington | $1.3M | $1.2M | $1.7M |
| 25 | Blindness-learning in New Dimensions INC Minneapolis | $1.1M | $1.1M | $1.1M |
| 26 | Gildas Club Twin Cities INC Minnetonka | $1.1M | $940K | $2.2M |
| 27 | Down Syndrome Association of Minnesota Saint Paul | $1.0M | $885K | $341K |
| 28 | Canby Developmental Achievement Center INC Canby | $937K | $937K | $1.9M |
| 29 | American Academy of Orofacial Pain Rochester | $667K | $667K | $265K |
| 30 | Down Syndrome Diagnosis Network Stillwater | $630K | $562K | $628K |
| 31 | American Brain Coalition Maple Grove | $616K | $616K | $825K |
| 32 | Minnesota Colorectal Cancer Research Foundation Minneapolis | $596K | $433K | $417K |
| 33 | T1international USA St. Louis Park | $567K | $567K | $525K |
| 34 | International Hepato-pancreato Biliary Association INC Rochester | $559K | $559K | $2.5M |
| 35 | Minnesota Lions Hearing Foundation INC Green Isle | $553K | $357K | $1.6M |
| 36 | Vlr Foundation Little Canada | $501K | $72K | $10.1M |
| 37 | Firefly Sisterhood Plymouth | $478K | $412K | $494K |
| 38 | American Academy of Oral Pathology Minneapolis | $436K | $409K | $841K |
| 39 | American Society of Neurorehabilitation Roseville | $398K | $398K | $571K |
| 40 | Minnesota Deaf Muslim Community Saint Paul | $397K | $397K | $95K |
| 41 | Brave Like Gabe Foundation Saint Paul | $370K | $323K | $683K |
| 42 | Brains Together for a Cure Rochester | $355K | $192K | $683K |
| 43 | Well Being Development Ely | $355K | $345K | $480K |
| 44 | Krabbe Connect Rosemount | $349K | $314K | $507K |
| 45 | Greg Marzolf Jr Foundation Saint Paul | $332K | $305K | $472K |
| 46 | Blooming Prairie Cancer Group Blmng Prairie | $313K | $278K | $84K |
| 47 | Rock from the Heart Delano | $291K | $290K | $80K |
| 48 | Spinal Cord Society Fergus Falls | $247K | $247K | $610K |
| 49 | Minnesota Lions Diabetes Foundation INC Saint Cloud | $246K | $246K | $151K |
| 50 | Infectious Disease Society for Obstetrics and Gynecology Burnsville | $239K | $239K | $387K |