| 1 | Wildlife Mississippi Stoneville | $13.3M | $13.2M | $82.8M |
| 2 | Eugenia Messick Foundation Olive Branch | $8.9M | $0 | $10.9M |
| 3 | Mississippi Aquarium Gulfport | $8.8M | $8.7M | $5.7M |
| 4 | Humane Society of South Ms Gulfport | $4.5M | $2.9M | $8.1M |
| 5 | Southern Pines Animal Shelter Hattiesburg | $3.9M | $3.9M | $2.3M |
| 6 | Pearl River County SPCA INC Picayune | $1.6M | $930K | $1.3M |
| 7 | Oktibbeha County Humane Society INC Starkville | $1.6M | $1.4M | $2.1M |
| 8 | Tupelo Lee Humane Society Tupelo | $1.6M | $1.6M | $2.4M |
| 9 | Community Animal Rescue & Adoption INC Clinton | $1.5M | $662K | $3.3M |
| 10 | St. Francis Animal Sanctuary Tylertown | $1.3M | $1.1M | $1.4M |
| 11 | Rocking R Ranch & Rescue INC Kosciusko | $1.2M | $1.2M | $53K |
| 12 | Mississippi Animal Rescue League Jackson | $1.2M | $1.2M | $3.8M |
| 13 | Tunica Humane Society Tunica | $754K | $718K | $561K |
| 14 | Mississippi Spay and Neuter - Span Richland | $726K | $721K | $985K |
| 15 | Hub City Humane Society Hattiesburg | $701K | $700K | $438K |
| 16 | Cedarhill Animal Sanctuary INC Caledonia | $686K | $631K | $924K |
| 17 | Animal Rescue Fund of Mississippi Jackson | $578K | $578K | $632K |
| 18 | Mississippi Wildlife Federation Jackson | $518K | $365K | $44K |
| 19 | Hoofbeats and Pawprints Rescue Natchez | $486K | $486K | $127K |
| 20 | West Point Clay County Animal Shelter West Point | $461K | $459K | $299K |
| 21 | Corinth Alcorn Animal Shelter INC Corinth | $374K | $374K | $115K |
| 22 | Columbus Lowndes Humane Society Columbus | $364K | $364K | $1.6M |
| 23 | Hoovers Hause All Dog Rescue Olive Branch | $363K | $363K | $19K |
| 24 | Natchez Adams County Humane Society Natchez | $338K | $338K | $2.5M |
| 25 | Tails of Hope Dog Rescue INC Walls | $330K | $330K | $5K |
| 26 | Amory Humane Society Amory | $312K | $312K | $345K |
| 27 | Clarksdale Animal Rescue Effort & Shelter INC Clarksdale | $307K | $307K | $501K |
| 28 | Mississippi Wildlife Heritage Foundation INC Leland | $287K | $287K | $884K |
| 29 | Woodside Wildlife Rescue Ltd Pass Chris | $245K | $245K | $22K |
| 30 | For Pets Sake Rescue Long Beach | $244K | $244K | $16K |
| 31 | Friends of the Animal Shelter in Hancock County Bay St. Louis | $241K | $239K | $228K |
| 32 | Creature Comforts Cc Quitman | $238K | $113K | $49K |
| 33 | Cheshire Abbey Jackson | $232K | $232K | $70K |
| 34 | Mississippi Horses INC Canton | $228K | $228K | $27K |
| 35 | Roadside Rescue Network Marion | $228K | $228K | $17K |
| 36 | Pals Rescue INC McComb | $223K | $223K | $239K |
| 37 | Stone County Society for the Prevention of Cruelty to Animals Wiggins | $219K | $219K | $292K |
| 38 | Tired Dog Rescue Gulfport | $212K | $207K | $90K |
| 39 | Delta Wind Birds Oxford | $192K | $192K | $215K |
| 40 | New Beginnings Animal Rescue Olive Branch | $186K | $186K | $6K |
| 41 | Vicksburg-warren Humane Society Vicksburg | $182K | $182K | $483K |
| 42 | American Pomeranian Club INC Ecru | $173K | $173K | $208K |
| 43 | Shaw Pit Bull Rescue Columbus | $166K | $162K | $120K |
| 44 | Friends of Jackson County Animal Shelter Pets Ocean Springs | $165K | $165K | $89K |
| 45 | Furry Angel Friends Animal Rescue Raymond | $145K | $145K | $9K |
| 46 | Safe Haven Rescue of Ms Monticello | $143K | $143K | $537 |
| 47 | Mississippi Wildlife Rehabilitation INC Coldwater | $143K | $139K | $380K |
| 48 | New Hope Animal Rescue Center Petal | $139K | $139K | $108K |
| 49 | Second Chance Animal Alliance Water Valley | $137K | $137K | $287K |
| 50 | Charlie S Crusaders Pet Rescue INC Horn Lake | $136K | $136K | $70K |