| 1 | Humane World for Animals INC Gaithersburg | $254.8M | $207.9M | $497.2M |
| 2 | National Aquarium INC Baltimore | $74.4M | $74.4M | $101.5M |
| 3 | The Humane League Rockville | $44.9M | $27.9M | $25.8M |
| 4 | American Association of Zoological Parks and Aquariums INC Silver Spring | $34.3M | $20.9M | $35.2M |
| 5 | The Maryland Zoological Society INC Baltimore | $28.6M | $28.2M | $79.6M |
| 6 | Aaalac International INC Frederick | $25.1M | $9.3M | $17.8M |
| 7 | Alley Cat Allies Incorporated Bethesda | $23.1M | $22.3M | $39.7M |
| 8 | Maryland SPCA INC Baltimore | $10.7M | $8.3M | $39.8M |
| 9 | National Aquarium Foundation INC Baltimore | $10.4M | $2.1M | $34.8M |
| 10 | Gentle Giants Draft Horse Rescue Society Ltd Mount Airy | $9.4M | $9.3M | $13.4M |
| 11 | Romanian League in Defense of Anima Ls Crofton | $7.3M | $7.3M | $777K |
| 12 | Baltimore Animal Rescue and Care Shelter INC Brooklyn | $6.9M | $6.8M | $4.7M |
| 13 | Last Chance Animal Rescue INC Waldorf | $6.7M | $6.7M | $9.9M |
| 14 | Humane Society of Washington County Incorporated Hagerstown | $5.5M | $3.7M | $11.2M |
| 15 | Humane Society of Baltimore County INC Reisterstown | $4.9M | $2.4M | $11.6M |
| 16 | Center for a Humane Economy INC Bethesda | $4.3M | $3.9M | $3.5M |
| 17 | Talbot Humane Co Easton | $4.2M | $1.7M | $6.6M |
| 18 | Montgomery County Humane Society INC Rockville | $4.0M | $2.9M | $11.9M |
| 19 | Days End Farm Horse Rescue INC Woodbine | $3.9M | $3.5M | $7.6M |
| 20 | Race for Life INC Annapolis | $3.8M | $0 | $5.7M |
| 21 | Wildlife Habitat Council INC Bethesda | $3.5M | $3.5M | $2.2M |
| 22 | Petconnect Rescue INC Potomac | $3.2M | $717K | $1.9M |
| 23 | Humane Society of Harford County INC Fallston | $3.0M | $2.4M | $8.1M |
| 24 | Alley Cat Rescue INC Mt Rainier | $3.0M | $3.0M | $2.7M |
| 25 | Hart for Animals INC McHenry | $2.9M | $2.7M | $3.5M |
| 26 | Society for the Prevention of Cruelty to Animals of a a Co Md in Annapolis | $2.9M | $2.6M | $18.0M |
| 27 | Humane Society of Carroll Co INC Westminster | $2.8M | $1.8M | $4.3M |
| 28 | Humane Society of Kent County Incorporated Chestertown | $2.6M | $1.5M | $6.0M |
| 29 | Born Free USA United with Animal Protection Institute Silver Spring | $2.6M | $2.6M | $2.3M |
| 30 | Global Wildlife Trust INC Thurmont | $2.5M | $2.4M | $2.1M |
| 31 | Montgomery County Society for the Prevention of Cruelty to Animals I Potomac | $2.5M | $2.4M | $3.4M |
| 32 | Second Chance Wildlife Center INC Clarksburg | $2.3M | $2.3M | $8.0M |
| 33 | Waterfowl Festival INC Easton | $2.2M | $2.2M | $5.3M |
| 34 | Biophilia Foundation INC Chester | $2.0M | $0 | $3.7M |
| 35 | Maryland Horse Breeders Association INC Reisterstown | $1.9M | $1.8M | $3.0M |
| 36 | Plumpton Park Zoological Gardens INC Rising Sun | $1.9M | $1.9M | $1.3M |
| 37 | Animal Outlook INC Takoma Park | $1.8M | $1.8M | $1.9M |
| 38 | Humane Society of Wicomico County INC Salisbury | $1.7M | $1.7M | $3.4M |
| 39 | Farm Animal Reform Movement INC Bethesda | $1.5M | $550K | $3.1M |
| 40 | Ferry Cove Shellfish INC Sherwood | $1.5M | $1.5M | $97K |
| 41 | Animals Angels Incorporated Westminster | $1.4M | $1.4M | $2.0M |
| 42 | Thomas E Quade Foundation INC Pasadena | $1.4M | $0 | $2.5M |
| 43 | Acvs Foundation INC Germantown | $1.4M | $613K | $6.0M |
| 44 | Rude Ranch Animal Rescue INC Millersville | $1.4M | $1.4M | $2.1M |
| 45 | Wicomico Valley Foundation of Southern Maryland INC Bryantown | $1.4M | $0 | $11.6M |
| 46 | Retired Racehorse Project Ltd Edgewater | $1.3M | $768K | $271K |
| 47 | United Spay Alliance Walkersville | $1.3M | $1.3M | $1.4M |
| 48 | Patuxent Animal Welfare Society Huntingtown | $1.3M | $1.3M | $1.2M |
| 49 | Wildfowl Trust of North America INC Grasonville | $1.2M | $1.2M | $3.5M |
| 50 | Companions and Animals for Reform and Equity INC Baltimore | $1.1M | $1.1M | $4.5M |