| 1 | Monterey Bay Aquarium Foundation Monterey | $1.0B | $208.1M | $837.7M |
| 2 | San Diego Zoo Wildlife Alliance San Diego | $547.4M | $437.6M | $1.0B |
| 3 | San Diego Humane Society and S P C a San Diego | $78.0M | $72.9M | $133.0M |
| 4 | Aquarium of the Pacific Long Beach | $62.8M | $59.3M | $100.0M |
| 5 | Wildlife Conservation Network INC San Francisco | $59.8M | $56.7M | $65.5M |
| 6 | Conservation Society of California Oakland | $58.2M | $31.5M | $94.6M |
| 7 | San Francisco Society for the Prevention of Cruelty to Animals San Francisco | $57.7M | $46.0M | $132.3M |
| 8 | Muttville San Francisco | $56.9M | $10.8M | $63.3M |
| 9 | Marine Mammal Center Sausalito | $55.4M | $22.9M | $54.9M |
| 10 | Peninsula Humane Society & SPCA Burlingame | $52.2M | $29.9M | $80.8M |
| 11 | Humane Society Silicon Valley Milpitas | $50.8M | $18.3M | $55.1M |
| 12 | The David Sheldrick Wildlife Trust USA INC Laguna Hills | $39.8M | $18.8M | $20.6M |
| 13 | Greater Los Angeles Zoo Association Glendale | $36.2M | $22.9M | $54.9M |
| 14 | Santa Barbara Humane Society for the Prevention of Cruelty to Anima Santa Barbara | $35.7M | $8.5M | $49.9M |
| 15 | Mercy for Animals Los Angeles | $35.3M | $23.3M | $30.2M |
| 16 | Fresnos Chaffee Zoo Corporation Fresno | $33.4M | $29.6M | $146.8M |
| 17 | Point Reyes Bird Observatory Petaluma | $32.7M | $31.7M | $26.4M |
| 18 | San Francisco Zoological Society San Francisco | $28.8M | $25.5M | $24.5M |
| 19 | Santa Barbara Zoological Foundation Santa Barbara | $28.0M | $21.8M | $47.0M |
| 20 | Marin Humane Society Novato | $27.4M | $14.0M | $31.5M |
| 21 | Society for the Prevention of Cruelty to Animals of Monterey Cty Salinas | $25.9M | $19.9M | $85.0M |
| 22 | Helen Woodward Animal Center Rcho Santa Fe | $24.7M | $24.0M | $84.2M |
| 23 | California Trout San Francisco | $23.4M | $22.9M | $13.3M |
| 24 | Sacramento Society for the Prevention of Cruelty to Animals Sacramento | $23.3M | $15.4M | $35.1M |
| 25 | Los Angeles S P C a Los Angeles | $21.8M | $13.4M | $71.1M |
| 26 | Joybound People and Pets Fka Tony Larussas Animal Rescue Foundation Walnut Creek | $19.6M | $13.4M | $89.0M |
| 27 | Animal Legal Defense Fund Sacramento | $18.0M | $18.0M | $23.6M |
| 28 | Pasadena Humane Society Pasadena | $16.3M | $15.8M | $43.9M |
| 29 | Revive & Restore Sausalito | $16.3M | $9.4M | $16.1M |
| 30 | California Deer Association Redding | $15.0M | $11.3M | $4.6M |
| 31 | Foster Friends Rescue Gardena | $14.9M | $14.7M | $14.5M |
| 32 | Humane Society of Pomona Valley INC Pomona | $14.4M | $12.7M | $25.7M |
| 33 | Inter-american Tropical Tuna Commission La Jolla | $14.3M | $14.3M | $9.8M |
| 34 | East Bay Society for the Prevention of Cruelty to Animals Oakland | $14.3M | $12.5M | $43.7M |
| 35 | National Marine Mammal Foundation INC San Diego | $13.9M | $13.9M | $4.1M |
| 36 | Rancho Coastal Humane Society Encinitas | $13.5M | $8.4M | $32.5M |
| 37 | Sacramento Zoological Society Sacramento | $12.5M | $12.4M | $27.4M |
| 38 | Placer County Society for the Prevention of Cruelty to Animals Roseville | $11.9M | $8.9M | $32.0M |
| 39 | Pet Care Foundation Northridge | $11.8M | $2.3M | $18.0M |
| 40 | Performing Animal Welfare Society Galt | $11.7M | $9.7M | $36.2M |
| 41 | Animal Samaritans Thousand Plms | $11.6M | $11.4M | $10.0M |
| 42 | Community Animal Medicine Project San Pedro | $11.5M | $11.5M | $7.2M |
| 43 | Wags and Walks Los Angeles | $11.4M | $6.6M | $7.7M |
| 44 | Humane America Animal Foundation Claremont | $10.2M | $10.2M | $39.8M |
| 45 | Prestons Planet Foundation INC Malibu | $9.2M | $9.2M | $9.1M |
| 46 | Wildaid INC San Francisco | $8.6M | $8.5M | $7.4M |
| 47 | Friends of the Palm Springs Animal Shelter Palm Springs | $8.3M | $7.9M | $5.1M |
| 48 | Haven Humane Society Redding | $8.2M | $4.7M | $15.7M |
| 49 | Friends of the Sea Lion INC Laguna Beach | $8.0M | $4.7M | $26.2M |
| 50 | Animal Charity Evaluators Covina | $7.8M | $7.8M | $5.5M |